| Literature DB >> 27578301 |
Chi Yao1, Peiyuan Wang1, Xiaomin Li1, Xiaoyu Hu2, Junli Hou1, Leyong Wang2, Fan Zhang1.
Abstract
Overcoming multidrug resistance is achieved by developing a novel drugdelivery-system paradigm based on azobenzene liposome and phosphatidylcholine-modified upconversion nanoparticle (UCNP) hybrid vesicles for controlled drug release using a nearinfrared (NIR) laser. Upon 980 nm light irradiation, the reversible photoisomerization of the azobenzene derivatives by simultaneous UV and visible light emitted from the UCNPs makes it possible to realize NIR-triggered release of the chemotherapeutic drug doxorubicin.Entities:
Keywords: azobenzene-liposomes; drug delivery; multidrug-resistant cancers; upconversion nanoparticles
Mesh:
Substances:
Year: 2016 PMID: 27578301 DOI: 10.1002/adma.201503799
Source DB: PubMed Journal: Adv Mater ISSN: 0935-9648 Impact factor: 30.849