S Takahashi1, M Hoshino2, K Takayama3, K Iseki4, R Sasaoka5, T Tsujio6, H Yasuda7, T Sasaki8, F Kanematsu9, H Kono10, H Toyoda2, H Nakamura2. 1. Department of Orthopaedic Surgery, Osaka City University Graduate School of Medicine, Osaka, Japan. shinji@med.osaka-cu.ac.jp. 2. Department of Orthopaedic Surgery, Osaka City University Graduate School of Medicine, Osaka, Japan. 3. Department of Orthopaedic Surgery, Seikeikai Hospital, Sakai, Osaka, Japan. 4. Department of Orthopaedic Surgery, Sato Hospital, Osaka, Japan. 5. Department of Orthopaedic Surgery, Yodogawa Christian Hospital, Osaka, Japan. 6. Department of Orthopaedic Surgery, Shiraniwa Hospital, Ikoma, Nara, Japan. 7. Department of Orthopaedic Surgery, Osaka General Hospital of West Japan Railway Company, Osaka, Japan. 8. Department of Orthopaedic Surgery, Nishinomiya Watanabe Hospital, Nishinomiya, Hyogo, Japan. 9. Department of Orthopaedic Surgery, Saiseikai Nakatsu Hospital, Osaka, Japan. 10. Department of Orthopaedic Surgery, Ishikiri Seiki Hospital, Higashi Osaka, Osaka, Japan.
Abstract
This study revealed the time course of osteoporotic vertebral fracture by magnetic resonance imaging using a simple classification. Signal changes were associated with the compression degree and mobility of the fractured vertebral body. This classification showed sufficient reliability in categorizing magnetic resonance imaging findings of osteoporotic vertebral fractures. INTRODUCTION: Magnetic resonance imaging (MRI) is useful in diagnosing osteoporotic vertebral fractures (OVFs). This study investigated the time course of OVFs by MRI using a simple classification. METHODS: This multicenter cohort study was performed from 2012 to 2015. Consecutive patients with ≤2-week-old OVFs were enrolled in 11 institutions. MRI was performed at enrollment and at 1-, 3-, 6-, and 12-month follow-up. Signal changes on T1-weighted imaging (T1WI), T2WI, and short τ inversion recovery (STIR) were classified according to signal intensity. Height and angular motion of vertebral bodies were also measured. RESULTS: The 6-month follow-up was completed by 153 patients. At enrollment, fractured vertebrae signal changes were 43 % diffuse and 57 % confined low on T1WI; on T2WI, 56, 24, and 5 % were confined low, high, and diffuse low, respectively; on STIR, 100 % were high. On T1WI, diffuse low remained most common (90 % at 1 month and 60 % at 3 months) until 6 and 12 months, when most were confined low (54 and 52 %, respectively). On T2WI, confined low remained most common (decreasing to 41 % at 12 months). On STIR, high signal change was shown in 98, 87, and 64 % at 3, 6, and 12 months, respectively. At 3, 6, and 12 months, diffuse low signal change was associated with significantly lower vertebral height, and high signal change was associated with significantly greater angular motion. CONCLUSIONS: MRI signal changes were associated with the compression degree and angular motion of fractured vertebrae. This classification showed sufficient reliability in categorizing MRI findings of OVFs.
This study revealed the time course of osteoporotic vertebral fracture by magnetic resonance imaging using a simple classification. Signal changes were associated with the compression degree and mobility of the fractured vertebral body. This classification showed sufficient reliability in categorizing magnetic resonance imaging findings of osteoporotic vertebral fractures. INTRODUCTION: Magnetic resonance imaging (MRI) is useful in diagnosing osteoporotic vertebral fractures (OVFs). This study investigated the time course of OVFs by MRI using a simple classification. METHODS: This multicenter cohort study was performed from 2012 to 2015. Consecutive patients with ≤2-week-old OVFs were enrolled in 11 institutions. MRI was performed at enrollment and at 1-, 3-, 6-, and 12-month follow-up. Signal changes on T1-weighted imaging (T1WI), T2WI, and short τ inversion recovery (STIR) were classified according to signal intensity. Height and angular motion of vertebral bodies were also measured. RESULTS: The 6-month follow-up was completed by 153 patients. At enrollment, fractured vertebrae signal changes were 43 % diffuse and 57 % confined low on T1WI; on T2WI, 56, 24, and 5 % were confined low, high, and diffuse low, respectively; on STIR, 100 % were high. On T1WI, diffuse low remained most common (90 % at 1 month and 60 % at 3 months) until 6 and 12 months, when most were confined low (54 and 52 %, respectively). On T2WI, confined low remained most common (decreasing to 41 % at 12 months). On STIR, high signal change was shown in 98, 87, and 64 % at 3, 6, and 12 months, respectively. At 3, 6, and 12 months, diffuse low signal change was associated with significantly lower vertebral height, and high signal change was associated with significantly greater angular motion. CONCLUSIONS: MRI signal changes were associated with the compression degree and angular motion of fractured vertebrae. This classification showed sufficient reliability in categorizing MRI findings of OVFs.
Entities:
Keywords:
Magnetic resonance imaging; Osteoporotic vertebral fractures; Simple classification; Time course
Authors: F C Oner; L M P Ramos; R K J Simmermacher; P T D Kingma; C H Diekerhof; W J A Dhert; A J Verbout Journal: Eur Spine J Date: 2002-01-29 Impact factor: 3.134
Authors: Klaus John Schnake; Thomas R Blattert; Patrick Hahn; Alexander Franck; Frank Hartmann; Bernhard Ullrich; Akhil Verheyden; Sven Mörk; Volker Zimmermann; Oliver Gonschorek; Michael Müller; Sebastian Katscher; Andre El Saman; Gholam Pajenda; Robert Morrison; Christian Schinkel; Stefan Piltz; Axel Partenheimer; Christian W Müller; Erol Gercek; Michael Scherer; Nabila Bouzraki; Frank Kandziora Journal: Global Spine J Date: 2018-09-07