Literature DB >> 2757739

[Octenidine dihydrochloride, properties of a new antimicrobial agent].

H P Harke1.   

Abstract

The chemical, antimicrobial and toxicological properties of Octenidine dihydrochloride - a compound belonging to the bipyridines - are briefly described. Already low concentrations (0.1% and less) of the substance are bactericidally and fungicidally effective. It is remarkable that this effect is practically as strong against grampositive as against gram negative germs. The compound is not absorbed by the skin. A systemic effect cannot be observed upon oral application within large of dosage scales. As active component in antiseptics the remanent effect has particularly to be emphasized even against transient germs reaching the skin after disinfection.

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Year:  1989        PMID: 2757739

Source DB:  PubMed          Journal:  Zentralbl Hyg Umweltmed        ISSN: 0934-8859


  7 in total

1.  Efficacy of octenidine hydrochloride for reducing Escherichia coli O157:H7, Salmonella spp., and Listeria monocytogenes on cattle hides.

Authors:  Sangeetha Ananda Baskaran; Abhinav Upadhyay; Indu Upadhyaya; Varunkumar Bhattaram; Kumar Venkitanarayanan
Journal:  Appl Environ Microbiol       Date:  2012-03-30       Impact factor: 4.792

2.  The effect of a combination of 0.1% octenidine dihydrochloride and 2% 2-phenoxyethanol (octenisept) on wound healing in pigs in vivo and its in vitro percutaneous permeation through intact and barrier disrupted porcine skin.

Authors:  Jessica Stahl; Michael Braun; Joerg Siebert; Manfred Kietzmann
Journal:  Int Wound J       Date:  2010-02       Impact factor: 3.315

3.  Effect of octenidine dihydrochloride on viability of protoscoleces in hepatic and pulmonary hydatid diseases.

Authors:  Ihsan Hakki Ciftci; Hidir Esme; Dursun Ali Sahin; Okan Solak; Murat Sezer; Osman Nuri Dilek
Journal:  J Natl Med Assoc       Date:  2007-06       Impact factor: 1.798

4.  The antimicrobial effect of Octenidine-dihydrochloride coated polymer tracheotomy tubes on Staphylococcus aureus and Pseudomonas aeruginosa colonisation.

Authors:  Michaela Zumtobel; Ojan Assadian; Matthias Leonhard; Maria Stadler; Berit Schneider
Journal:  BMC Microbiol       Date:  2009-07-25       Impact factor: 3.605

5.  Effect of octenidine hydrochloride on planktonic cells and biofilms of Listeria monocytogenes.

Authors:  Mary Anne Roshni Amalaradjou; Carol E Norris; Kumar Venkitanarayanan
Journal:  Appl Environ Microbiol       Date:  2009-04-17       Impact factor: 4.792

6.  The percutaneous permeation of a combination of 0.1% octenidine dihydrochloride and 2% 2-phenoxyethanol (octenisept®) through skin of different species in vitro.

Authors:  Jessica Stahl; Michael Braun; Joerg Siebert; Manfred Kietzmann
Journal:  BMC Vet Res       Date:  2011-08-11       Impact factor: 2.741

7.  Cholorhexidine, octenidine or povidone iodine for catheter related infections: A randomized controlled trial.

Authors:  Ayten Bilir; Birgül Yelken; Ayse Erkan
Journal:  J Res Med Sci       Date:  2013-06       Impact factor: 1.852

  7 in total

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