Warning: Undefined array key "mm" in /www/wwwroot/www.ai-bt.com/si.php on line 10 Deprecated: trim(): Passing null to parameter #1 ($string) of type string is deprecated in /www/wwwroot/www.ai-bt.com/si.php on line 10 Specification and epigenetic programming of the human germ line.

Literature DB >> 27573372

Specification and epigenetic programming of the human germ line.

Walfred W C Tang^1,2, Toshihiro Kobayashi^1,2, Naoko Irie^1,2, Sabine Dietmann^1,3, M Azim Surani^1,2.

Abstract

Primordial germ cells (PGCs), the precursors of sperm and eggs, are established in perigastrulation-stage embryos in mammals. Signals from extra-embryonic tissues induce a unique gene regulatory network in germline-competent cells for PGC specification. This network also initiates comprehensive epigenome resetting, including global DNA demethylation and chromatin reorganization. Mouse germline development has been studied extensively, but the extent to which such knowledge applies to humans was unclear. Here, we review the latest advances in human PGC specification and epigenetic reprogramming. The overall developmental dynamics of human and mouse germline cells appear to be similar, but there are crucial mechanistic differences in PGC specification, reflecting divergence in the regulation of pluripotency and early development.

Entities: Chemical

Mesh：

Year: 2016 PMID： 27573372 DOI： 10.1038/nrg.2016.88

Source DB: PubMed Journal: Nat Rev Genet ISSN： 1471-0056 Impact factor: 53.242

172 in total

1. Spontaneous differentiation of germ cells from human embryonic stem cells in vitro.

Authors: Amander T Clark; Megan S Bodnar; Mark Fox; Ryan T Rodriquez; Michael J Abeyta; Meri T Firpo; Renee A Reijo Pera
Journal: Hum Mol Genet Date: 2004-02-12 Impact factor: 6.150

2. Sequence-specific regulator Prdm14 safeguards mouse ESCs from entering extraembryonic endoderm fates.

Authors: Ziyang Ma; Tomek Swigut; Anton Valouev; Alvaro Rada-Iglesias; Joanna Wysocka
Journal: Nat Struct Mol Biol Date: 2010-12-23 Impact factor: 15.369

3. Bone morphogenetic proteins induce germ cell differentiation from human embryonic stem cells.

Authors: Kehkooi Kee; Joanna M Gonsalves; Amander T Clark; Renee A Reijo Pera
Journal: Stem Cells Dev Date: 2006-12 Impact factor: 3.272

4. DNA Demethylation Dynamics in the Human Prenatal Germline.

Authors: Sofia Gkountela; Kelvin X Zhang; Tiasha A Shafiq; Wen-Wei Liao; Joseph Hargan-Calvopiña; Pao-Yang Chen; Amander T Clark
Journal: Cell Date: 2015-05-21 Impact factor: 41.582

5. Paracrine effects of embryo-derived FGF4 and BMP4 during pig trophoblast elongation.

Authors: Griselda Valdez Magaña; Aida Rodríguez; Haixin Zhang; Robert Webb; Ramiro Alberio
Journal: Dev Biol Date: 2014-01-18 Impact factor: 3.582

6. A genome-wide RNAi screen reveals determinants of human embryonic stem cell identity.

Authors: Na-Yu Chia; Yun-Shen Chan; Bo Feng; Xinyi Lu; Yuriy L Orlov; Dimitri Moreau; Pankaj Kumar; Lin Yang; Jianming Jiang; Mei-Sheng Lau; Mikael Huss; Boon-Seng Soh; Petra Kraus; Pin Li; Thomas Lufkin; Bing Lim; Neil D Clarke; Frederic Bard; Huck-Hui Ng
Journal: Nature Date: 2010-10-17 Impact factor: 49.962

7. The ontogeny of cKIT+ human primordial germ cells proves to be a resource for human germ line reprogramming, imprint erasure and in vitro differentiation.

Authors: Sofia Gkountela; Ziwei Li; John J Vincent; Kelvin X Zhang; Angela Chen; Matteo Pellegrini; Amander T Clark
Journal: Nat Cell Biol Date: 2012-12-16 Impact factor: 28.824

8. Generation of induced pluripotent stem cells without Myc from mouse and human fibroblasts.

Authors: Masato Nakagawa; Michiyo Koyanagi; Koji Tanabe; Kazutoshi Takahashi; Tomoko Ichisaka; Takashi Aoi; Keisuke Okita; Yuji Mochiduki; Nanako Takizawa; Shinya Yamanaka
Journal: Nat Biotechnol Date: 2007-11-30 Impact factor: 54.908

9. X chromosome activity in mouse XX primordial germ cells.

Authors: Susana M Chuva de Sousa Lopes; Katsuhiko Hayashi; Tanya C Shovlin; Will Mifsud; M Azim Surani; Anne McLaren
Journal: PLoS Genet Date: 2008-02 Impact factor: 5.917

Review 10. Primordial germ cells: the first cell lineage or the last cells standing?

Authors: Andrew D Johnson; Ramiro Alberio
Journal: Development Date: 2015-08-15 Impact factor: 6.868

127 in total

1. Developmental origins of transgenerational sperm DNA methylation epimutations following ancestral DDT exposure.

Authors: Millissia Ben Maamar; Eric Nilsson; Ingrid Sadler-Riggleman; Daniel Beck; John R McCarrey; Michael K Skinner
Journal: Dev Biol Date: 2018-11-27 Impact factor: 3.582

Review 2. Connecting the Dots Between Fatty Acids, Mitochondrial Function, and DNA Methylation in Atherosclerosis.

Authors: Silvio Zaina; Gertrud Lund
Journal: Curr Atheroscler Rep Date: 2017-09 Impact factor: 5.113

Review 3. Making headway towards understanding how epigenetic mechanisms contribute to early-life effects.

Authors: Maja Vukic; Haoyu Wu; Lucia Daxinger
Journal: Philos Trans R Soc Lond B Biol Sci Date: 2019-04-15 Impact factor: 6.237

4. Developing differences: early-life effects and evolutionary medicine.

Authors: Bram Kuijper; Mark A Hanson; Emma I K Vitikainen; Harry H Marshall; Susan E Ozanne; Michael A Cant
Journal: Philos Trans R Soc Lond B Biol Sci Date: 2019-04-15 Impact factor: 6.237

Review 5. Epigenetic changes in mammalian gametes throughout their lifetime: the four seasons metaphor.

Authors: Peera Wasserzug-Pash; Michael Klutstein
Journal: Chromosoma Date: 2019-04-27 Impact factor: 4.316

Review 6. The interplay of epigenetic marks during stem cell differentiation and development.

Authors: Yaser Atlasi; Hendrik G Stunnenberg
Journal: Nat Rev Genet Date: 2017-08-14 Impact factor: 53.242

7. Accurate annotation of accessible chromatin in mouse and human primordial germ cells.

Authors: Jingyi Li; Shijun Shen; Jiayu Chen; Wenqiang Liu; Xiaocui Li; Qianshu Zhu; Beiying Wang; Xiaolong Chen; Li Wu; Mingzhu Wang; Liang Gu; Hong Wang; Jiqing Yin; Cizhong Jiang; Shaorong Gao
Journal: Cell Res Date: 2018-10-10 Impact factor: 25.617