Eri Hayashida1, Toshinori Hirai2, Hideo Nakamura3, Masafumi Kidoh4, Minako Azuma1, Yasuhiko Iryo1, Mika Kitajima1, Seitaro Oda1, Daisuke Utsunomiya1, Takeshi Nakaura1, Yasuyuki Yamashita1. 1. Departments of Diagnostic Radiology, Faculty of Life Sciences, Graduate School of Medical Sciences, Kumamoto University, 1-1-1 Honjo, Kumamoto, 860-8556, Japan. 2. Department of Radiology, Faculty of Medicine, University of Miyazaki, Miyazaki, Japan. 3. Neurosurgery, Graduate School of Medical Sciences, Kumamoto University, 1-1-1, Honjo, Kumamoto, 860-8556, Japan. 4. Departments of Diagnostic Radiology, Faculty of Life Sciences, Graduate School of Medical Sciences, Kumamoto University, 1-1-1 Honjo, Kumamoto, 860-8556, Japan. masafkidoh@yahoo.co.jp.
Abstract
PURPOSE: To assess whether 320-section low-dose dynamic volume computed tomography (320-LDVCT) with adaptive iterative dose reduction (AIDR) adds value to 3-T MRI for the preoperative evaluation of brain tumors. METHODS: The study population was comprised of 16 consecutive patients with brain tumors who, in addition to preoperative 3-T MRI, underwent 320-LDVCT with AIDR. Two radiologists independently evaluated the CT and MRI studies; one measured the relative cerebral blood volume (rCBV) in the tumor and contralateral brain on CT and MR perfusion maps. Interobserver agreement was assessed by κ statistics. RESULTS: In 3 of 16 patients (19 %), 320-LDVCT added diagnostic value to 3-T MRI studies with respect to the visualization of feeders (κ = 0.77), and in 12 (75 %) it helped the delineation of venous structures (κ = 0.71) and the relationship between the tumor and adjacent vessels (κ = 0.85). The average standardized rCBV value was 12.2 ± 2.40 (range 0.7-36.6) on MR and 8.80 ± 2.77 (range 0.8-38.0) on CT perfusion studies; the correlation between these values was very strong (r = 0.92, p < 0.0001). According to the neurosurgeons, 320-LDVCT added helpful information for surgery in 4 patients (25 %). CONCLUSION: The 320-LDVCT can add value to 3-T MRI for the tumor feeders and relationship between the tumor and adjacent vessels.
PURPOSE: To assess whether 320-section low-dose dynamic volume computed tomography (320-LDVCT) with adaptive iterative dose reduction (AIDR) adds value to 3-T MRI for the preoperative evaluation of brain tumors. METHODS: The study population was comprised of 16 consecutive patients with brain tumors who, in addition to preoperative 3-T MRI, underwent 320-LDVCT with AIDR. Two radiologists independently evaluated the CT and MRI studies; one measured the relative cerebral blood volume (rCBV) in the tumor and contralateral brain on CT and MR perfusion maps. Interobserver agreement was assessed by κ statistics. RESULTS: In 3 of 16 patients (19 %), 320-LDVCT added diagnostic value to 3-T MRI studies with respect to the visualization of feeders (κ = 0.77), and in 12 (75 %) it helped the delineation of venous structures (κ = 0.71) and the relationship between the tumor and adjacent vessels (κ = 0.85). The average standardized rCBV value was 12.2 ± 2.40 (range 0.7-36.6) on MR and 8.80 ± 2.77 (range 0.8-38.0) on CT perfusion studies; the correlation between these values was very strong (r = 0.92, p < 0.0001). According to the neurosurgeons, 320-LDVCT added helpful information for surgery in 4 patients (25 %). CONCLUSION: The 320-LDVCT can add value to 3-T MRI for the tumor feeders and relationship between the tumor and adjacent vessels.
Authors: B R Rosen; J W Belliveau; B R Buchbinder; R C McKinstry; L M Porkka; D N Kennedy; M S Neuder; C R Fisel; H J Aronen; K K Kwong Journal: Magn Reson Med Date: 1991-06 Impact factor: 4.668
Authors: S Nishimura; T Hirai; Y Shigematsu; M Kitajima; M Morioka; Y Kai; R Minoda; H Uetani; R Murakami; Y Yamashita Journal: AJNR Am J Neuroradiol Date: 2011-11-24 Impact factor: 3.825
Authors: H Uetani; M Akter; T Hirai; Y Shigematsu; M Kitajima; Y Kai; S Yano; H Nakamura; K Makino; M Azuma; R Murakami; Y Yamashita Journal: AJNR Am J Neuroradiol Date: 2012-10-18 Impact factor: 3.825