Mougnyan Cox1, Bryan Pukenas2, Michael Poplawski3, Aaron Bress2, Diane Deely3, Adam Flanders3. 1. Department of Radiology, Thomas Jefferson University, 132 South 10th Street, 1087 Main Building, Philadelphia, PA 19107. Electronic address: mougnyan.cox@gmail.edu. 2. Department of Radiology, Hospital of the University of Pennsylvania, Philadelphia, Pennsylvania 19104. 3. Department of Radiology, Thomas Jefferson University, 132 South 10th Street, 1087 Main Building, Philadelphia, PA 19107.
Abstract
RATIONALE AND OBJECTIVES: The cervical spine is a high-risk area for percutaneous biopsy compared to the thoracic and lumbar regions. Biopsy of the cervical spine is less commonly undertaken, and previously published series on diagnostic yield and safety of cervical spine biopsy have been limited to 12 patients or less. The purpose of our study is to further define the diagnostic yield of computed tomography (CT)-guided biopsy for bony lesions identified in the cervical spine, by combining data from two large tertiary care referral centers. METHODS: A retrospective review of an imaging database was performed to identify all percutaneous CT-guided biopsies of the cervical spine performed at two tertiary care hospitals from 2010 to 2015. Core biopsies were obtained whenever possible and supplemented with fine-needle aspiration in some cases. Histopathologic results of the biopsy were recorded, as were changes in subsequent management, need for repeat biopsy, and complications. RESULTS: Forty-three patients underwent CT-guided biopsy of the cervical spine. Sufficient tissue for histopathologic analysis was obtained in 41 out of 43 cases, for a yield of 95%. One case was false-negative and one was deemed insufficient by the pathologist for diagnostic purposes; in both of these cases, only a fine-needle aspiration was obtained. There were no immediate or delayed complications. CONCLUSIONS: Percutaneous biopsy of the cervical spine is a safe and high-yield method of obtaining a tissue diagnosis when performed under image guidance with CT.
RATIONALE AND OBJECTIVES: The cervical spine is a high-risk area for percutaneous biopsy compared to the thoracic and lumbar regions. Biopsy of the cervical spine is less commonly undertaken, and previously published series on diagnostic yield and safety of cervical spine biopsy have been limited to 12 patients or less. The purpose of our study is to further define the diagnostic yield of computed tomography (CT)-guided biopsy for bony lesions identified in the cervical spine, by combining data from two large tertiary care referral centers. METHODS: A retrospective review of an imaging database was performed to identify all percutaneous CT-guided biopsies of the cervical spine performed at two tertiary care hospitals from 2010 to 2015. Core biopsies were obtained whenever possible and supplemented with fine-needle aspiration in some cases. Histopathologic results of the biopsy were recorded, as were changes in subsequent management, need for repeat biopsy, and complications. RESULTS: Forty-three patients underwent CT-guided biopsy of the cervical spine. Sufficient tissue for histopathologic analysis was obtained in 41 out of 43 cases, for a yield of 95%. One case was false-negative and one was deemed insufficient by the pathologist for diagnostic purposes; in both of these cases, only a fine-needle aspiration was obtained. There were no immediate or delayed complications. CONCLUSIONS: Percutaneous biopsy of the cervical spine is a safe and high-yield method of obtaining a tissue diagnosis when performed under image guidance with CT.
Authors: Michael C Burke; Ankur Garg; Jonathan M Youngner; Swati D Deshmukh; Imran M Omar Journal: Skeletal Radiol Date: 2018-10-20 Impact factor: 2.199
Authors: Patricia Laborda-Vidal; Myriam Martín; Marc Orts-Porcar; Laura Vilalta; Antonio Melendez-Lazo; Alejandra García de Carellán; Carlos Ros Journal: Animals (Basel) Date: 2022-06-30 Impact factor: 3.231