Literature DB >> 27554257

Androgenetic Alopecia: An Update of Treatment Options.

Yanna Kelly1,2,3, Aline Blanco4, Antonella Tosti5.   

Abstract

Androgenetic alopecia (AGA) is characterized by a non-scarring progressive miniaturization of the hair follicle in predisposed men and women with a pattern distribution. Although AGA is a very prevalent condition, approved therapeutic options are limited. This article discusses the current treatment alternatives including their efficacy, safety profile, and quality of evidence. Finasteride and minoxidil for male androgenetic alopecia and minoxidil for female androgenetic alopecia still are the therapeutic options with the highest level evidence. The role of antiandrogens for female patients, the importance of adjuvant therapies, as well as new drugs and procedures are also addressed.

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Year:  2016        PMID: 27554257     DOI: 10.1007/s40265-016-0629-5

Source DB:  PubMed          Journal:  Drugs        ISSN: 0012-6667            Impact factor:   9.546


  155 in total

Review 1.  Minoxidil use in dermatology, side effects and recent patents.

Authors:  Alfredo Rossi; Carmen Cantisani; Luca Melis; Alessandra Iorio; Elisabetta Scali; Stefano Calvieri
Journal:  Recent Pat Inflamm Allergy Drug Discov       Date:  2012-05

2.  Dermal β-catenin activity in response to epidermal Wnt ligands is required for fibroblast proliferation and hair follicle initiation.

Authors:  Demeng Chen; Andrew Jarrell; Canting Guo; Richard Lang; Radhika Atit
Journal:  Development       Date:  2012-04       Impact factor: 6.868

3.  The Effect of Platelet-Rich Plasma in Hair Regrowth: A Randomized Placebo-Controlled Trial.

Authors:  Pietro Gentile; Simone Garcovich; Alessandra Bielli; Maria Giovanna Scioli; Augusto Orlandi; Valerio Cervelli
Journal:  Stem Cells Transl Med       Date:  2015-09-23       Impact factor: 6.940

Review 4.  Finasteride treatment of hair loss in women.

Authors:  Stephen M Stout; Janice L Stumpf
Journal:  Ann Pharmacother       Date:  2010-05-04       Impact factor: 3.154

5.  Platelet-rich plasma for androgenetic alopecia: a pilot study.

Authors:  Giovanni Schiavone; Desanka Raskovic; Joseph Greco; Damiano Abeni
Journal:  Dermatol Surg       Date:  2014-09       Impact factor: 3.398

6.  A randomized, single-blind trial of 5% minoxidil foam once daily versus 2% minoxidil solution twice daily in the treatment of androgenetic alopecia in women.

Authors:  Ulrike Blume-Peytavi; Kathrin Hillmann; Ekkehart Dietz; Douglas Canfield; Natalie Garcia Bartels
Journal:  J Am Acad Dermatol       Date:  2011-06-23       Impact factor: 11.527

7.  Biologic variability of prostate-specific antigen and its usefulness as a marker for prostate cancer: effects of finasteride. The Finasteride PSA Study Group.

Authors:  J E Oesterling; J Roy; A Agha; T Shown; T Krarup; T Johansen; M Lagerkvist; G Gormley; M Bach; J Waldstreicher
Journal:  Urology       Date:  1997-07       Impact factor: 2.649

8.  Persistent sexual side effects of finasteride for male pattern hair loss.

Authors:  Michael S Irwig; Swapna Kolukula
Journal:  J Sex Med       Date:  2011-03-18       Impact factor: 3.802

9.  Prevalence of male and female pattern hair loss in Maryborough.

Authors:  Desmond C C Gan; Rodney D Sinclair
Journal:  J Investig Dermatol Symp Proc       Date:  2005-12

Review 10.  Female pattern alopecia: current perspectives.

Authors:  Lauren L Levy; Jason J Emer
Journal:  Int J Womens Health       Date:  2013-08-29
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  27 in total

Review 1.  Dermatologic Conditions in Transgender Populations.

Authors:  Howa Yeung; Benjamin Kahn; Bao Chau Ly; Vin Tangpricha
Journal:  Endocrinol Metab Clin North Am       Date:  2019-06       Impact factor: 4.741

Review 2.  Review of quality of life studies in women with alopecia.

Authors:  D S Davis; V D Callender
Journal:  Int J Womens Dermatol       Date:  2018-01-09

3.  Systematic Review and Meta-analysis of the Association Between Metabolic Syndrome and Androgenetic Alopecia.

Authors:  Yueqi Qiu; Xingyu Zhou; Siqi Fu; Shuaihantian Luo; Yaping Li
Journal:  Acta Derm Venereol       Date:  2022-02-08       Impact factor: 3.875

4.  Patient Satisfaction and Quality of Life Among Adult Women with Androgenetic Alopecia Using 5% Topical Minoxidil.

Authors:  Renata Indelicato Zac; Adilson da Costa
Journal:  J Clin Aesthet Dermatol       Date:  2021-05-01

5.  Histopathological Findings of Uncomplicated Hair Transplant for Male Androgenetic Alopecia: Can Lichen Planopilaris Features Be Present?

Authors:  Andressa Silva Alcântara; Aline Donati; Maria Victoria Suárez; Ivan José Netto Pereira; Neusa Yuriko Sakai Valente; Nilceo Schwery Michalany; Cristiano Luiz Horta de Lima; Leticia Arsie Contin
Journal:  Skin Appendage Disord       Date:  2020-06-24

Review 6.  Treatment options for androgenetic alopecia: Efficacy, side effects, compliance, financial considerations, and ethics.

Authors:  Mark S Nestor; Glynis Ablon; Anita Gade; Haowei Han; Daniel L Fischer
Journal:  J Cosmet Dermatol       Date:  2021-11-06       Impact factor: 2.189

7.  Annurca Apple Nutraceutical Formulation Enhances Keratin Expression in a Human Model of Skin and Promotes Hair Growth and Tropism in a Randomized Clinical Trial.

Authors:  Gian Carlo Tenore; Domenico Caruso; Giuseppe Buonomo; Maria D'Avino; Rita Santamaria; Carlo Irace; Marialuisa Piccolo; Maria Maisto; Ettore Novellino
Journal:  J Med Food       Date:  2017-09-28       Impact factor: 2.786

Review 8.  Hormonal therapy in female pattern hair loss.

Authors:  Kevin R Brough; Rochelle R Torgerson
Journal:  Int J Womens Dermatol       Date:  2017-02-24

9.  Cardiometabolic Risk Factors in Rosuvastatin-Treated Men with Mixed Dyslipidemia and Early-Onset Androgenic Alopecia.

Authors:  Robert Krysiak; Marcin Basiak; Bogusław Okopień
Journal:  Molecules       Date:  2021-05-11       Impact factor: 4.411

10.  Atypical Case of Minoxidil-Induced Generalized Anasarca and Pleuropericardial Effusion.

Authors:  Wahab A Gbadamosi; Jacqueline Melvin; Marvin Lopez
Journal:  Cureus       Date:  2021-06-03
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