Literature DB >> 27541846

Deadly falls: operative versus nonoperative management of Type II odontoid process fracture in octogenarians.

Christopher S Graffeo1, Avital Perry1, Ross C Puffer1, Lucas P Carlstrom1, Wendy Chang1, Grant W Mallory1, Michelle J Clarke1.   

Abstract

OBJECTIVE Type II odontoid fracture is a common injury among elderly patients, particularly given their predisposition toward low-energy falls. Previous studies have demonstrated a survival advantage following early surgery among patients older than 65 years, yet octogenarians represent a medically distinct and rapidly growing population. The authors compared operative and nonoperative management in patients older than 79 years. METHODS A single-center prospectively maintained trauma database was reviewed using ICD-9 codes to identify octogenarians with C-2 cervical fractures between 1998 and 2014. Cervical CT images were independently reviewed by blinded neurosurgeons to confirm a Type II fracture pattern. Prospectively recorded outcomes included Glasgow Coma Scale (GCS) score, Abbreviated Injury Scale (AIS) score, Injury Severity Score (ISS), additional cervical fracture, and cord injury. Primary end points were mortality at 30 days and at 1 year. Statistical tests included the Student t-test, chi-square test, Fisher's exact test, Kaplan-Meier test, and Cox proportional hazard. RESULTS A total of 111 patients met inclusion criteria (94 nonoperative and 17 operative [15 posterior and 2 anterior]). Mortality data were available for 100% of patients. The mean age was 87 years (range 80-104 years). Additional cervical fracture, spinal cord injury, GCS score, AIS score, and ISS were not associated with either management strategy at the time of presentation. The mean time to death or last follow-up was 22 months (range 0-129 months) and was nonsignificant between operative and nonoperative groups (p = 0.3). Overall mortality was 13% in-hospital, 26% at 30 days, and 41% at 1 year. Nonoperative and operative mortality rates were not significant at any time point (12% vs 18%, p = 0.5 [in-hospital]; 27% vs 24%, p = 0.8 [30-day]; and 41% vs 41%, p = 1.0 [1-year]). Kaplan-Meier analysis did not demonstrate a survival advantage for either management strategy. Spinal cord injury, GCS score, AIS score, and ISS were significantly associated with 30-day and 1-year mortality; however, Cox modeling was not significant for any variable. Additional cervical fracture was not associated with increased mortality. The rate of nonhome disposition was not significant between the groups. CONCLUSIONS Type II odontoid fracture is associated with high morbidity among octogenarians, with 41% 1-year mortality independent of intervention-a dramatic decrease from actuarial survival rates for all 80-, 90-, and 100-year-old Americans. Poor outcome is associated with spinal cord injury, GCS score, AIS score, and ISS.

Entities:  

Keywords:  AIS = Abbreviated Injury Scale; GCS = Glasgow Coma Scale; ISS = Injury Severity Score; SCI = spinal cord injury; Type II odontoid fracture; cervical; elderly populations; nonoperative management; spine trauma

Mesh:

Year:  2016        PMID: 27541846     DOI: 10.3171/2016.3.SPINE151202

Source DB:  PubMed          Journal:  J Neurosurg Spine        ISSN: 1547-5646


  14 in total

1.  Letter: Reconsidering Bone Morphogenetic Protein in the Cervical Spine: Selective Use for Managing Type II Odontoid Fractures in the Elderly.

Authors:  Francis J Jareczek; Kingsley O Abode-Iyamah; Efrem M Cox; Nader S Dahdaleh; Patrick W Hitchon; Matthew A Howard
Journal:  Oper Neurosurg (Hagerstown)       Date:  2017-12-01       Impact factor: 2.703

2.  Duration of External Neck Stabilisation (DENS) following odontoid fracture in older or frail adults: protocol for a randomised controlled trial of collar versus no collar.

Authors:  Julie Woodfield; Ellie Edlmann; Polly L Black; Julia Boyd; Phillip Correia Copley; Gina Cranswick; Helen Eborall; Catriona Keerie; Sadaquate Khan; Julia Lawton; David J Lowe; John Norrie; Angela Niven; Matthew J Reed; Susan Deborah Shenkin; Patrick Statham; Andrew Stoddart; James Tomlinson; Paul M Brennan
Journal:  BMJ Open       Date:  2022-07-15       Impact factor: 3.006

3.  Identifying factors influencing mortality in patients aged over 65 following an acute type II odontoid process fracture. A retrospective cohort study.

Authors:  Timothy Lukins; Lana Nguyen; Mitchell A Hansen; Richard D Ferch
Journal:  Eur Spine J       Date:  2021-02-22       Impact factor: 3.134

4.  Traumatic spinal cord injuries in geriatric population: etiology, management, and complications.

Authors:  Karan Arul; Laurence Ge; Tochukwu Ikpeze; Avionna Baldwin; Addisu Mesfin
Journal:  J Spine Surg       Date:  2019-03

5.  Commentary on the management of type II odontoid process fractures in octogenarians: Article by Graffeo et al. and Editorial by Falavigna (J Neurosurgery Spine August 19, 2016).

Authors:  Nancy E Epstein
Journal:  Surg Neurol Int       Date:  2016-11-21

6.  Surgical vs. non-surgical management of displaced type-2 odontoid fractures in patients aged 75 years and older: study protocol for a randomised controlled trial.

Authors:  Anna-Lena Robinson; Gregor Schmeiser; Yohan Robinson; Claes Olerud
Journal:  Trials       Date:  2018-08-22       Impact factor: 2.279

7.  Odontoid Type II fractures in elderly: what are the real management goals and how to best achieve them? A multicenter European study on functional outcome.

Authors:  Salvatore Chibbaro; Charles-Henry Mallereau; Mario Ganau; Ismail Zaed; Maria Teresa Bozzi; Antonino Scibilia; Helene Cebula; Irene Ollivier; Marie-Pierre Loit; Dominique Chaussemy; Hugo-Andres Coca; Guillaume Dannhoff; Antonio Romano; Beniamino Nannavecchia; Arthur Gubian; Giorgio Spatola; Francesco Signorelli; Corrado Iaccarino; Raoul Pop; François Proust; Seyyid Baloglu; Julien Todeschi
Journal:  Neurosurg Rev       Date:  2021-07-07       Impact factor: 3.042

8.  C1-C2 fractures in asymptomatic elderly patients with minor head trauma: evaluation with a dedicated head CT protocol.

Authors:  Silvia Squarza; Carla Luisa Uggetti; Marco Angelo Politi; Lorenzo Carlo Pescatori; Raffaele Bisogno; Adriana Campi; Paolo Reganati; Maurizio Cariati
Journal:  Radiol Bras       Date:  2019 Jan-Feb

9.  Comparative Propensity-Weighted Mortality After Isolated Acute Traumatic Axis Fractures in Older Adults.

Authors:  Michael P Catalino; Virginia Pate; Til Stürmer; Deb A Bhowmick
Journal:  Geriatr Orthop Surg Rehabil       Date:  2020-03-30

10.  Predictors of 30-Day Unplanned Readmissions, Complications, and Mortality Following Operative Management of C2 Fractures.

Authors:  David N Bernstein; Caroline Thirukumaran; Brandon Raudenbush; Robert W Molinari; Emmanuel N Menga; Addisu Mesfin
Journal:  Global Spine J       Date:  2019-05-01
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.