Literature DB >> 27536345

Insomnia and dementia: is agomelatine treatment helpful? Case report and review of the literature.

Vesile Altınyazar1, Nefati Kiylioglu2.   

Abstract

The treatment of sleep disorders in Alzheimer's disease (AD) may be quite challenging in elderly patients because of drug side effects or interactions and comorbid local or systemic diseases. Here, we report a patient with AD, who was suffering from severe insomnia and depression. We ordered agomelatine for the treatment of insomnia in this patient, and it was quite helpful not only for insomnia but also for depression and for the cognitive symptoms related with dementia. Our aim was to share these observations for similar patients.

Entities:  

Keywords:  Alzheimer’s disease; agomelatine; dementia; sleep

Year:  2016        PMID: 27536345      PMCID: PMC4971602          DOI: 10.1177/2045125316646064

Source DB:  PubMed          Journal:  Ther Adv Psychopharmacol        ISSN: 2045-1253


  61 in total

1.  Depressive symptoms and subjective and objective sleep in community-dwelling older women.

Authors:  Jeanne E Maglione; Sonia Ancoli-Israel; Katherine W Peters; Misti L Paudel; Kristine Yaffe; Kristine E Ensrud; Katie L Stone
Journal:  J Am Geriatr Soc       Date:  2012-03-16       Impact factor: 5.562

Review 2.  Sleep in normal aging and dementia.

Authors:  D L Bliwise
Journal:  Sleep       Date:  1993-01       Impact factor: 5.849

Review 3.  Connections between sleep and cognition in older adults.

Authors:  Kristine Yaffe; Cherie M Falvey; Tina Hoang
Journal:  Lancet Neurol       Date:  2014-10       Impact factor: 44.182

4.  Chronic sleep restriction causes a decrease in hippocampal volume in adolescent rats, which is not explained by changes in glucocorticoid levels or neurogenesis.

Authors:  A Novati; H J Hulshof; J M Koolhaas; P J Lucassen; P Meerlo
Journal:  Neuroscience       Date:  2011-06-17       Impact factor: 3.590

Review 5.  Insomnia as a predictor of depression: a meta-analytic evaluation of longitudinal epidemiological studies.

Authors:  Chiara Baglioni; Gemma Battagliese; Bernd Feige; Kai Spiegelhalder; Christoph Nissen; Ulrich Voderholzer; Caterina Lombardo; Dieter Riemann
Journal:  J Affect Disord       Date:  2011-02-05       Impact factor: 4.839

6.  A multicenter, placebo-controlled trial of melatonin for sleep disturbance in Alzheimer's disease.

Authors:  Clifford Singer; Rochelle E Tractenberg; Jeffrey Kaye; Kim Schafer; Anthony Gamst; Michael Grundman; Ronald Thomas; Leon J Thal
Journal:  Sleep       Date:  2003-11-01       Impact factor: 5.849

Review 7.  Sleep and Alzheimer disease pathology--a bidirectional relationship.

Authors:  Yo-El S Ju; Brendan P Lucey; David M Holtzman
Journal:  Nat Rev Neurol       Date:  2013-12-24       Impact factor: 42.937

8.  Melatonin fails to improve sleep or agitation in double-blind randomized placebo-controlled trial of institutionalized patients with Alzheimer disease.

Authors:  Philip R Gehrman; Donald J Connor; Jennifer L Martin; Tamar Shochat; Jody Corey-Bloom; Sonia Ancoli-Israel
Journal:  Am J Geriatr Psychiatry       Date:  2009-02       Impact factor: 4.105

9.  Memory facilitating effects of agomelatine in the novel object recognition memory paradigm in the rat.

Authors:  Valérie Bertaina-Anglade; Christophe Drieu-La-Rochelle; Elisabeth Mocaër; Laure Seguin
Journal:  Pharmacol Biochem Behav       Date:  2011-02-22       Impact factor: 3.533

Review 10.  Evaluating the Evidence Surrounding Pontine Cholinergic Involvement in REM Sleep Generation.

Authors:  Kevin P Grace; Richard L Horner
Journal:  Front Neurol       Date:  2015-09-01       Impact factor: 4.003

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  5 in total

1.  The extent of involvement of ouabain, hippocampal expression of Na+/K+-ATPase, and corticosterone/melatonin receptors ratio in modifying stress-induced behavior differs according to the stressor in context.

Authors:  S Abdelmissih; W M Sayed; L A Rashed; M M Kamel; M A Eshra; M I Attallah; R A-R El-Naggar
Journal:  Braz J Med Biol Res       Date:  2022-07-13       Impact factor: 2.904

2.  Inhibitory effect of celecoxib on agomelatine metabolism in vitro and in vivo.

Authors:  Jiayang He; Ping Fang; Xiang Zheng; Chenchen Wang; Tenghui Liu; Bowen Zhang; Jian Wen; Ren-Ai Xu
Journal:  Drug Des Devel Ther       Date:  2018-03-09       Impact factor: 4.162

3.  Clinical Practice Guideline on Management of Sleep Disorders in the Elderly.

Authors:  Samir Kumar Praharaj; Ravi Gupta; Navendu Gaur
Journal:  Indian J Psychiatry       Date:  2018-02       Impact factor: 1.759

Review 4.  Serotonin 2 Receptors, Agomelatine, and Behavioral and Psychological Symptoms of Dementia in Alzheimer's Disease.

Authors:  Hui-Hua Li; Xiao-Yan Yao; Sheng Tao; Xue Sun; Pan-Pan Li; Xi-Xin Li; Zhu-Li Liu; Chao Ren
Journal:  Behav Neurol       Date:  2021-03-31       Impact factor: 3.342

5.  Agomelatine Prevents Amyloid Plaque Deposition, Tau Phosphorylation, and Neuroinflammation in APP/PS1 Mice.

Authors:  Xiao-Bo Yang; Heng-Bing Zu; Yong-Fei Zhao; Kai Yao
Journal:  Front Aging Neurosci       Date:  2022-01-27       Impact factor: 5.750

  5 in total

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