Literature DB >> 22428562

Depressive symptoms and subjective and objective sleep in community-dwelling older women.

Jeanne E Maglione1, Sonia Ancoli-Israel, Katherine W Peters, Misti L Paudel, Kristine Yaffe, Kristine E Ensrud, Katie L Stone.   

Abstract

OBJECTIVES: To examine the relationship between depressive symptoms and subjective and objective sleep in older women.
DESIGN: Cross-sectional.
SETTING: Four U.S. clinical centers. PARTICIPANTS: Three thousand forty-five community-dwelling women aged 70 and older. MEASUREMENTS: Depressive symptoms were assessed using the Geriatric Depression Scale, categorizing participants as normal (0-2, reference), some depressive symptoms (3-5), or depressed (≥ 6). Subjective sleep quality and daytime sleepiness were assessed using the Pittsburgh Sleep Quality Index (PSQI) and Epworth Sleepiness Scale (ESS). Objective sleep measures were assessed using wrist actigraphy.
RESULTS: In multivariable-adjusted models, there were graded associations between greater level of depressive symptoms and worse subjective sleep quality and more subjective daytime sleepiness (P-trends < .001). Women with some depressive symptoms (odds ratio (OR) = 1.82, 95% confidence interval (CI) = 1.48-2.24) and depressed (OR = 2.84, 95% CI = 2.08-3.86) women had greater odds of reporting poor sleep (PSQI>5). Women with some depressive symptoms (OR = 1.97, 95% CI = 1.47-2.64) and depressed women (OR = 1.70, 95% CI = 1.12-2.58) had greater odds of reporting excessive daytime sleepiness (ESS>10). There were also graded associations between greater level of depressive symptoms and objectively measured wake after sleep onset (WASO) (P-trend = .03) and wake episodes longer than 5 minutes (P-trend = .006). Depressed women had modestly higher odds of WASO of 1 hour or longer (OR = 1.37, 95% CI = 1.03-1.83). Women with some depressive symptoms (OR = 1.49, 95% CI = 1.19-1.86) and depressed women (OR = 2.04, 95% CI = 1.52-2.74) had greater odds of being in the highest quartile for number of nap episodes longer than 5 minutes. No associations between depressive symptom level and prolonged sleep latency, poor sleep efficiency, or short or long total sleep time were found.
CONCLUSION: Greater depressive symptom levels were associated with more subjective sleep disturbance and objective evidence of sleep fragmentation and napping.
© 2012, Copyright the Authors Journal compilation © 2012, The American Geriatrics Society.

Entities:  

Mesh:

Year:  2012        PMID: 22428562      PMCID: PMC3517685          DOI: 10.1111/j.1532-5415.2012.03908.x

Source DB:  PubMed          Journal:  J Am Geriatr Soc        ISSN: 0002-8614            Impact factor:   5.562


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