| Literature DB >> 27533984 |
Rocio Hinojar1, Jose Julio Jiménez-Natcher2, Covadonga Fernández-Golfín2, Jose Luis Zamorano2.
Abstract
New oral anticoagulants (NOACs) are an alternative for vitamin K antagonists (VKAs) to prevent stroke in patients with non-valvular atrial fibrillation (AF). Unlike VKAs, these anticoagulants do not require routine INR monitoring and possess favorable pharmacological properties. The lack of an effective antidote, their cost, or reservations in patients with kidney disease may explain their slow rate of expansion. Safe and effective use of these new drugs will depend on clinical experience amongst the medical community. This review discusses the current NOACs, providing practical and easy-to-use algorithms for application in the clinical routine. Published on behalf of the European Society of Cardiology. All rights reserved.Entities:
Keywords: Atrial fibrillation; New oral anticoagulants; Stroke
Mesh:
Substances:
Year: 2015 PMID: 27533984 DOI: 10.1093/ehjcvp/pvv002
Source DB: PubMed Journal: Eur Heart J Cardiovasc Pharmacother