Literature DB >> 2753199

Studies on ferritin in rat liver and spleen during repeated phlebotomy.

L J Mostert1, M I Cleton, W C de Bruijn, J F Koster, H G van Eijk.   

Abstract

1. The ferritin content of liver and spleen in normal and iron-loaded rats decreased during repeated phlebotomy. 2. During increased iron demand, ferritin is degraded in toto. 3. With the ESI and EELS technique the iron distribution was followed in different cell types and cellular compartments. 4. We have demonstrated two methods of iron mobilisation: (a) catabolism of lysosomal ferritin in toto and (b) delivery of ferritin from parenchymal cell into the bile and degradation of ferritin in toto.

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Year:  1989        PMID: 2753199     DOI: 10.1016/0020-711x(89)90025-6

Source DB:  PubMed          Journal:  Int J Biochem        ISSN: 0020-711X


  5 in total

1.  Analysis of iron-containing compounds in different compartments of the rat liver after iron loading.

Authors:  P L Ringeling; M I Cleton; M I Huijskes-Heins; M J Seip; W C de Bruijn; H G van Eijk
Journal:  Biol Met       Date:  1990

2.  Comparison of cytosolic products formed in rat liver in response to parenteral and dietary iron loading.

Authors:  P L Ringeling; M I Cleton; M I Huijskes-Heins; W C de Bruijn; H G van Eijk
Journal:  Biol Trace Elem Res       Date:  1992-10       Impact factor: 3.738

3.  Effect of phlebotomy on the ferritin iron content in the rat liver as determined morphometrically with the use of electron energy loss spectroscopy.

Authors:  M I Cleton; L J Mostert; L W Sorber; A A de Jong; C M de Jeu-Jaspars; W C de Bruijn
Journal:  Cell Tissue Res       Date:  1989-06       Impact factor: 5.249

4.  Lysosomal and cytosolic ferritins. A biochemical and electron-spectroscopic study.

Authors:  P L Ringeling; M I Cleton; M J Kroos; L W Sorber; W C de Bruyn; P M Harrison; H G van Eijk
Journal:  Biol Met       Date:  1989

5.  NCOA4 is regulated by HIF and mediates mobilization of murine hepatic iron stores after blood loss.

Authors:  Xiuqi Li; Larisa Lozovatsky; Abitha Sukumaran; Luis Gonzalez; Anisha Jain; Dong Liu; Nadia Ayala-Lopez; Karin E Finberg
Journal:  Blood       Date:  2020-12-03       Impact factor: 22.113

  5 in total

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