Warning: Undefined array key "mm" in /www/wwwroot/www.ai-bt.com/si.php on line 10 Deprecated: trim(): Passing null to parameter #1 ($string) of type string is deprecated in /www/wwwroot/www.ai-bt.com/si.php on line 10 Non-coding RNAs and disease: the classical ncRNAs make a comeback.

Literature DB >> 27528754

Non-coding RNAs and disease: the classical ncRNAs make a comeback.

Rogerio Alves de Almeida¹, Marcin G Fraczek¹, Steven Parker¹, Daniela Delneri¹, Raymond T O'Keefe².

Abstract

Many human diseases have been attributed to mutation in the protein coding regions of the human genome. The protein coding portion of the human genome, however, is very small compared with the non-coding portion of the genome. As such, there are a disproportionate number of diseases attributed to the coding compared with the non-coding portion of the genome. It is now clear that the non-coding portion of the genome produces many functional non-coding RNAs and these RNAs are slowly being linked to human diseases. Here we discuss examples where mutation in classical non-coding RNAs have been attributed to human disease and identify the future potential for the non-coding portion of the genome in disease biology.

Entities: Chemical Disease Gene Mutation Species

Keywords: RNase mitochondrial RNA processing (MRP); ncRNA; small nuclear RNA (snRNA); small nucleolar RNA (snoRNA); tRNA; telomerase RNA component (TERC)

Mesh：

Substances：

Year: 2016 PMID： 27528754 PMCID： PMC6042638 DOI： 10.1042/BST20160089

Source DB: PubMed Journal: Biochem Soc Trans ISSN： 0300-5127 Impact factor: 5.407

47 in total

1. The splicing of U12-type introns can be a rate-limiting step in gene expression.

Authors: Abhijit A Patel; Matthew McCarthy; Joan A Steitz
Journal: EMBO J Date: 2002-07-15 Impact factor: 11.598

2. Systematic curation and analysis of genomic variations and their potential functional consequences in snoRNA loci.

Authors: Deeksha Bhartiya; Jatin Talwar; Yasha Hasija; Vinod Scaria
Journal: Hum Mutat Date: 2012-07-06 Impact factor: 4.878

Review 3. Of proteins and RNA: the RNase P/MRP family.

Authors: Olga Esakova; Andrey S Krasilnikov
Journal: RNA Date: 2010-07-13 Impact factor: 4.942

4. Mutation of a U2 snRNA gene causes global disruption of alternative splicing and neurodegeneration.

Authors: Yichang Jia; John C Mu; Susan L Ackerman
Journal: Cell Date: 2012-01-20 Impact factor: 41.582

Review 5. Human mitochondrial tRNAs: biogenesis, function, structural aspects, and diseases.

Authors: Tsutomu Suzuki; Asuteka Nagao; Takeo Suzuki
Journal: Annu Rev Genet Date: 2011-09-06 Impact factor: 16.830

6. Compound heterozygosity of low-frequency promoter deletions and rare loss-of-function mutations in TXNL4A causes Burn-McKeown syndrome.

Authors: Dagmar Wieczorek; William G Newman; Thomas Wieland; Tea Berulava; Maria Kaffe; Daniela Falkenstein; Christian Beetz; Elisabeth Graf; Thomas Schwarzmayr; Sofia Douzgou; Jill Clayton-Smith; Sarah B Daly; Simon G Williams; Sanjeev S Bhaskar; Jill E Urquhart; Beverley Anderson; James O'Sullivan; Odile Boute; Jasmin Gundlach; Johanna Christina Czeschik; Anthonie J van Essen; Filiz Hazan; Sarah Park; Anne Hing; Alma Kuechler; Dietmar R Lohmann; Kerstin U Ludwig; Elisabeth Mangold; Laura Steenpaß; Michael Zeschnigk; Johannes R Lemke; Charles Marques Lourenco; Ute Hehr; Eva-Christina Prott; Melanie Waldenberger; Anne C Böhmer; Bernhard Horsthemke; Raymond T O'Keefe; Thomas Meitinger; John Burn; Hermann-Josef Lüdecke; Tim M Strom
Journal: Am J Hum Genet Date: 2014-11-26 Impact factor: 11.025

7. Telomere dysfunction triggers developmentally regulated germ cell apoptosis.

Authors: M T Hemann; K L Rudolph; M A Strong; R A DePinho; L Chin; C W Greider
Journal: Mol Biol Cell Date: 2001-07 Impact factor: 4.138

8. Association of TALS developmental disorder with defect in minor splicing component U4atac snRNA.

Authors: Patrick Edery; Charles Marcaillou; Mourad Sahbatou; Audrey Labalme; Joelle Chastang; Renaud Touraine; Emmanuel Tubacher; Faiza Senni; Michael B Bober; Sheela Nampoothiri; Pierre-Simon Jouk; Elisabeth Steichen; Siren Berland; Annick Toutain; Carol A Wise; Damien Sanlaville; Francis Rousseau; Françoise Clerget-Darpoux; Anne-Louise Leutenegger
Journal: Science Date: 2011-04-08 Impact factor: 47.728

9. mtDNA Variation and Analysis Using Mitomap and Mitomaster.

Authors: Marie T Lott; Jeremy N Leipzig; Olga Derbeneva; H Michael Xie; Dimitra Chalkia; Mahdi Sarmady; Vincent Procaccio; Douglas C Wallace
Journal: Curr Protoc Bioinformatics Date: 2013-12

10. An RNA-dependent RNA polymerase formed by TERT and the RMRP RNA.

Authors: Yoshiko Maida; Mami Yasukawa; Miho Furuuchi; Timo Lassmann; Richard Possemato; Naoko Okamoto; Vivi Kasim; Yoshihide Hayashizaki; William C Hahn; Kenkichi Masutomi
Journal: Nature Date: 2009-08-23 Impact factor: 49.962

28 in total

1. The long noncoding RNA MALAT1 predicts human pancreatic islet isolation quality.

Authors: Wilson Km Wong; Guozhi Jiang; Anja E Sørensen; Yi Vee Chew; Cody Lee-Maynard; David Liuwantara; Lindy Williams; Philip J O'Connell; Louise T Dalgaard; Ronald C Ma; Wayne J Hawthorne; Mugdha V Joglekar; Anandwardhan A Hardikar
Journal: JCI Insight Date: 2019-07-30

2. Maternally inherited 133kb deletion of 14q32 causing Kagami-Ogata syndrome.

Authors: Hou-Sung Jung; Stephanie E Vallee; Mary Beth Dinulos; Gregory J Tsongalis; Joel A Lefferts
Journal: J Hum Genet Date: 2018-09-19 Impact factor: 3.172

Review 3. The Importance of Being Modified: The Role of RNA Modifications in Translational Fidelity.

Authors: Paul F Agris; Amithi Narendran; Kathryn Sarachan; Ville Y P Väre; Emily Eruysal
Journal: Enzymes Date: 2017-04-22

4. LncRNAs in neuropsychiatric disorders and computational insights for their prediction.

Authors: Cinmoyee Baruah; Prangan Nath; Pankaj Barah
Journal: Mol Biol Rep Date: 2022-09-12 Impact factor: 2.742

5. Circ-FOXM1 promotes the proliferation, migration and EMT process of osteosarcoma cells through FOXM1-mediated Wnt pathway activation.

Authors: Hao Zhang; Qiongqiong Zhou; Weimin Shen
Journal: J Orthop Surg Res Date: 2022-07-07 Impact factor: 2.677

Review 6. Non-coding RNAs: new biomarkers and therapeutic targets for esophageal cancer.

Authors: Xiaobin Hou; Jiaxin Wen; Zhipeng Ren; Guoliang Zhang
Journal: Oncotarget Date: 2017-06-27

7. A resource for functional profiling of noncoding RNA in the yeast Saccharomyces cerevisiae.

Authors: Steven Parker; Marcin G Fraczek; Jian Wu; Sara Shamsah; Alkisti Manousaki; Kobchai Dungrattanalert; Rogerio Alves de Almeida; Diego Estrada-Rivadeneyra; Walid Omara; Daniela Delneri; Raymond T O'Keefe
Journal: RNA Date: 2017-05-03 Impact factor: 4.942

8. Large-scale profiling of noncoding RNA function in yeast.

Authors: Steven Parker; Marcin G Fraczek; Jian Wu; Sara Shamsah; Alkisti Manousaki; Kobchai Dungrattanalert; Rogerio Alves de Almeida; Edith Invernizzi; Tim Burgis; Walid Omara; Sam Griffiths-Jones; Daniela Delneri; Raymond T O'Keefe
Journal: PLoS Genet Date: 2018-03-12 Impact factor: 5.917

9. Circ_0072088 promotes the development of non-small cell lung cancer via the miR-377-5p/NOVA2 axis.

Authors: Zhaofeng Tan; Fang Cao; Bin Jia; Lei Xia
Journal: Thorac Cancer Date: 2020-06-11 Impact factor: 3.500

10. Differential Expression and Bioinformatics Analysis of CircRNA in PDGF-BB-Induced Vascular Smooth Muscle Cells.

Authors: Jiangtian Tian; Yahong Fu; Qi Li; Ying Xu; Xiangwen Xi; Yuqi Zheng; Li Yu; Zhuozhong Wang; Bo Yu; Jinwei Tian
Journal: Front Genet Date: 2020-05-29 Impact factor: 4.599