Literature DB >> 27527922

Old versus new: Progress in reaching the goals of the new kidney allocation system.

Connie J Wang1, James B Wetmore2, Ajay K Israni3.   

Abstract

As demand for kidney transplant continues to grow faster than organ availability, appropriate allocation of deceased donor kidneys is an acute priority. Increased longevity matching is central to this effort. To foster equitable and efficient utilization of deceased donor kidneys, a new kidney allocation system (KAS) was introduced in December 2014. Major achievements in the 1year after its implementation include a reduction in age-mismatch and an increase in access to transplant for historically disadvantaged candidates, such as those with very high levels of panel-reactive antibodies or long dialysis duration. However, the rate of discarded kidneys has not decreased, and an increase in A2/A2B transplants has yet to be realized. Organs are now shared more often at the regional and national levels, with some regions experiencing an increase in transplants and other a decrease. While implementation of the KAS has been associated with the attainment of key goals, the kidney transplant community must remain vigilant about potential untoward consequences, including reductions in transplant rates for specific groups such as pediatric patients. More time is required before firm conclusions about the long-term effects of the new KAS can be rendered.
Copyright © 2016 American Society for Histocompatibility and Immunogenetics. All rights reserved.

Entities:  

Keywords:  Deceased donor kidney transplant; End-stage renal disease (ESRD); Estimated posttransplant survival (EPTS); Kidney donor profile index (KDPI); Kidney transplant; New kidney allocation system (KAS)

Mesh:

Substances:

Year:  2016        PMID: 27527922     DOI: 10.1016/j.humimm.2016.08.007

Source DB:  PubMed          Journal:  Hum Immunol        ISSN: 0198-8859            Impact factor:   2.850


  10 in total

1.  Association of the kidney allocation system with dialysis exposure before deceased donor kidney transplantation by preemptive wait-listing status.

Authors:  Meera N Harhay; Michael O Harhay; Karthik Ranganna; Suzanne M Boyle; Lissa Levin Mizrahi; Stephen Guy; Gregory E Malat; Gary Xiao; David J Reich; Rachel E Patzer
Journal:  Clin Transplant       Date:  2018-09-15       Impact factor: 2.863

Review 2.  Kidney transplantation of highly sensitized recipients under the new kidney allocation system: A reflection from five different transplant centers across the United States.

Authors:  Ronald F Parsons; Jayme E Locke; Robert R Redfield; Garrett R Roll; Matthew H Levine
Journal:  Hum Immunol       Date:  2016-10-20       Impact factor: 2.850

Review 3.  Identification of Multiple Hub Genes in Acute Kidney Injury after Kidney Transplantation by Bioinformatics Analysis.

Authors:  Sang-Wook Kang; Sung-Wook Kang; Ju-Yeon Ban; Min-Su Park
Journal:  Medicina (Kaunas)       Date:  2022-05-20       Impact factor: 2.948

4.  Race/ethnicity is associated with ABO-nonidentical liver transplantation in the United States.

Authors:  Jin Ge; John P Roberts; Jennifer C Lai
Journal:  Clin Transplant       Date:  2017-06-19       Impact factor: 2.863

5.  Racial/ethnic disparities in waitlisting for deceased donor kidney transplantation 1 year after implementation of the new national kidney allocation system.

Authors:  Xingyu Zhang; Taylor A Melanson; Laura C Plantinga; Mohua Basu; Stephen O Pastan; Sumit Mohan; David H Howard; Jason M Hockenberry; Michael D Garber; Rachel E Patzer
Journal:  Am J Transplant       Date:  2018-04-18       Impact factor: 8.086

Review 6.  Delayed Graft Function: The AKI of Kidney Transplantation.

Authors:  Roslyn B Mannon
Journal:  Nephron       Date:  2018-07-13       Impact factor: 2.847

7.  Nonimmunologic Donor-Recipient Pairing, HLA Matching, and Graft Loss in Deceased Donor Kidney Transplantation.

Authors:  Amanda Jean Vinson; Bryce A Kiberd; Roger B Davis; Karthik K Tennankore
Journal:  Transplant Direct       Date:  2018-12-19

8.  Impact of Change in Allocation Score Methodology on Post Kidney Transplant Average Length of Stay.

Authors:  Hanadi Y Hamadi; Hani M Wadei; Jing Xu; Dayana Martinez; Aaron Spaulding; Shehzad K Niazi; Tambi Jarmi
Journal:  J Clin Med Res       Date:  2022-03-25

9.  Textbook Outcome as a Quality Metric in Living and Deceased Donor Kidney Transplantation.

Authors:  Austin D Schenk; April J Logan; Jeffrey M Sneddon; Daria Faulkner; Jing L Han; Guy N Brock; William K Washburn
Journal:  J Am Coll Surg       Date:  2022-06-17       Impact factor: 6.532

10.  Human extracellular microvesicles from renal tubules reverse kidney ischemia-reperfusion injury in rats.

Authors:  James M Dominguez; Jesus H Dominguez; Danhui Xie; K J Kelly
Journal:  PLoS One       Date:  2018-08-27       Impact factor: 3.240

  10 in total

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