Literature DB >> 27518251

Estimation of Physiologic Ability and Surgical Stress (E-PASS) versus modified E-PASS for prediction of postoperative complications in elderly patients who undergo gastrectomy for gastric cancer.

Yuki Kitano1, Masaaki Iwatsuki1, Junji Kurashige1, Daisuke Kuroda1, Keisuke Kosumi1, Yoshifumi Baba1, Yasuo Sakamoto1, Yuji Miyamoto1, Naoya Yoshida1, Yoshio Haga2, Hideo Baba3.   

Abstract

BACKGROUND: Improvements in operative technique and perioperative management have resulted in increasing numbers of elderly patients undergoing gastrectomy for gastric cancer (GC). We evaluated the accuracy of Estimation of Physiologic Ability and Surgical Stress (E-PASS) and modified (m)E-PASS scores in predicting postoperative complications in elderly patients with GC.
METHODS: We retrospectively analyzed short-term outcomes in 413 patients who underwent gastrectomy for GC between 2005 and 2014. They were divided into two groups: Group N comprised 341 non-elderly patients <80 years of age and Group E comprised 72 elderly patients ≥80 years of age. We calculated the E-PASS and mE-PASS scores and evaluated the correlation between the comprehensive risk score (CRS) and occurrence of postoperative complications.
RESULTS: Morbidity rates were 25.5 % in Group N and 31.9 % in Group E. In Group N, the CRS values of both the E-PASS (P < 0.0001) and mE-PASS (P < 0.0001) scores were significantly higher in patients with complications than in those without complications. In Group E, although the E-PASS CRS was significantly higher in patients with complications than in patients without complications (P = 0.01), the mE-PASS CRS fixed (CRSf) score was not significantly correlated with the occurrence of postoperative complications (P = 0.08).
CONCLUSION: Both E-PASS and mE-PASS can be used to predict the occurrence of postoperative complications in GC patients undergoing gastrectomy. However, the E-PASS CRS is more accurate for elderly patients because variations in intraoperative parameters such as operation time, blood loss, and extent of skin incision have a strong influence on the occurrence of postoperative complications.

Entities:  

Keywords:  Elderly; Physiological stress; Postoperative complications/mortality

Mesh:

Year:  2016        PMID: 27518251     DOI: 10.1007/s10147-016-1028-3

Source DB:  PubMed          Journal:  Int J Clin Oncol        ISSN: 1341-9625            Impact factor:   3.402


  26 in total

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Authors:  S Yamashita; Y Haga; E Nemoto; S Nagai; M Ohta
Journal:  Eur Surg Res       Date:  2004 Jul-Aug       Impact factor: 1.745

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Authors:  Tomoyuki Wakahara; Nozomi Ueno; Tetsuo Maeda; Kiyonori Kanemitsu; Takuro Yoshikawa; Shinobu Tsuchida; Akihiro Toyokawa
Journal:  Ann Gastroenterol       Date:  2018-05-09

2.  Is it safe to perform gastrectomy in gastric cancer patients aged 80 or older?: A meta-analysis and systematic review.

Authors:  Yixin Xu; Yibo Wang; Cheng Xi; Nianyuan Ye; Xuezhong Xu
Journal:  Medicine (Baltimore)       Date:  2019-06       Impact factor: 1.817

3.  Development and validation of grade-based prediction models for postoperative morbidity in gastric cancer resection using a Japanese web-based nationwide registry.

Authors:  Yoshio Haga; Hiroaki Miyata; Akira Tsuburaya; Mitsukazu Gotoh; Kazuhiro Yoshida; Hiroyuki Konno; Yasuyuki Seto; Yoshiyuki Fujiwara; Hideo Baba
Journal:  Ann Gastroenterol Surg       Date:  2019-06-20
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