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Literature DB >> 27514701

Closing the gap: astrocytes and brain metastasis.

Gino B Ferraro¹, David P Kodack¹, Vasileios Askoxylakis¹, Rakesh K Jain¹.

Abstract

Astrocytes are emerging as essential regulators of brain metastasis progression. In a current issue of Nature, Chen et al. identify a novel mechanism of astrocyte-carcinoma interaction and exploit vulnerabilities therein to slow brain metastatic growth in pre-clinical models.

Entities: Disease

Mesh：

Substances：

Year: 2016 PMID： 27514701 PMCID： PMC5034114 DOI： 10.1038/cr.2016.96

Source DB: PubMed Journal: Cell Res ISSN： 1001-0602 Impact factor: 25.617

12 in total

1. Reactions of astrocytes and microglial cells around hematogenous metastases of the human brain. Expression of endothelin-like immunoreactivity in reactive astrocytes and activation of microglial cells.

Authors: M Zhang; Y Olsson
Journal: J Neurol Sci Date: 1995-12 Impact factor: 3.181

2. Microenvironment-induced PTEN loss by exosomal microRNA primes brain metastasis outgrowth.

Authors: Lin Zhang; Siyuan Zhang; Jun Yao; Frank J Lowery; Qingling Zhang; Wen-Chien Huang; Ping Li; Min Li; Xiao Wang; Chenyu Zhang; Hai Wang; Kenneth Ellis; Mujeeburahiman Cheerathodi; Joseph H McCarty; Diane Palmieri; Jodi Saunus; Sunil Lakhani; Suyun Huang; Aysegul A Sahin; Kenneth D Aldape; Patricia S Steeg; Dihua Yu
Journal: Nature Date: 2015-10-19 Impact factor: 49.962

3. Cross-species hybridization of microarrays for studying tumor transcriptome of brain metastasis.

Authors: Eun Sung Park; Sun Jin Kim; Seung Wook Kim; Se-Lyun Yoon; Sun-Hee Leem; Sang-Bae Kim; Soo Mi Kim; Yun-Yong Park; Jae-Ho Cheong; Hyun Goo Woo; Gordon B Mills; Isaiah J Fidler; Ju-Seog Lee
Journal: Proc Natl Acad Sci U S A Date: 2011-10-10 Impact factor: 11.205

4. Real-time imaging reveals the single steps of brain metastasis formation.

Authors: Yvonne Kienast; Louisa von Baumgarten; Martin Fuhrmann; Wolfgang E F Klinkert; Roland Goldbrunner; Jochen Herms; Frank Winkler
Journal: Nat Med Date: 2009-12-20 Impact factor: 53.440

5. Astrocytes upregulate survival genes in tumor cells and induce protection from chemotherapy.

Authors: Sun-Jin Kim; Jang-Seong Kim; Eun Sung Park; Ju-Seog Lee; Qingtang Lin; Robert R Langley; Marva Maya; Junqin He; Seung-Wook Kim; Zhang Weihua; Krishnakumar Balasubramanian; Dominic Fan; Gordon B Mills; Mien-Chie Hung; Isaiah J Fidler
Journal: Neoplasia Date: 2011-03 Impact factor: 5.715

Review 6. Emerging strategies for treating brain metastases from breast cancer.

Authors: David P Kodack; Vasileios Askoxylakis; Gino B Ferraro; Dai Fukumura; Rakesh K Jain
Journal: Cancer Cell Date: 2015-02-09 Impact factor: 31.743

7. Serpins promote cancer cell survival and vascular co-option in brain metastasis.

Authors: Manuel Valiente; Anna C Obenauf; Xin Jin; Qing Chen; Xiang H-F Zhang; Derek J Lee; Jamie E Chaft; Mark G Kris; Jason T Huse; Edi Brogi; Joan Massagué
Journal: Cell Date: 2014-02-27 Impact factor: 41.582

8. Genes that mediate breast cancer metastasis to the brain.

Authors: Paula D Bos; Xiang H-F Zhang; Cristina Nadal; Weiping Shu; Roger R Gomis; Don X Nguyen; Andy J Minn; Marc J van de Vijver; William L Gerald; John A Foekens; Joan Massagué
Journal: Nature Date: 2009-05-06 Impact factor: 49.962

9. Trastuzumab emtansine (T-DM1) renders HER2+ breast cancer highly susceptible to CTLA-4/PD-1 blockade.

Authors: Philipp Müller; Matthias Kreuzaler; Tarik Khan; Daniela S Thommen; Kea Martin; Katharina Glatz; Spasenija Savic; Nadia Harbeck; Ulrike Nitz; Oleg Gluz; Michael von Bergwelt-Baildon; Hans Kreipe; Sai Reddy; Matthias Christgen; Alfred Zippelius
Journal: Sci Transl Med Date: 2015-11-25 Impact factor: 17.956

10. Carcinoma-astrocyte gap junctions promote brain metastasis by cGAMP transfer.

Authors: Qing Chen; Adrienne Boire; Xin Jin; Manuel Valiente; Ekrem Emrah Er; Alejandro Lopez-Soto; Leni Jacob; Ruzeen Patwa; Hardik Shah; Ke Xu; Justin R Cross; Joan Massagué
Journal: Nature Date: 2016-05-18 Impact factor: 49.962

2 in total

1. Orchestration of the crosstalk between astrocytes and cancer cells affects the treatment and prognosis of lung cancer sufferers with brain metastasis.

Authors: Wangshu Dai; Hongcheng Zhu; Guangzong Chen; Hao Gu; Yihang Gu; Xinchen Sun; Xiaoning Zeng
Journal: J Thorac Dis Date: 2016-11 Impact factor: 2.895

Review 2. microRNAs Orchestrate Pathophysiology of Breast Cancer Brain Metastasis: Advances in Therapy.

Authors: Ranjana K Kanchan; Jawed A Siddiqui; Sidharth Mahapatra; Surinder K Batra; Mohd W Nasser
Journal: Mol Cancer Date: 2020-02-15 Impact factor: 27.401

2 in total