Literature DB >> 2750588

Lipid peroxidation in normal and ulcerated gastric mucosa of rats treated with pentacaine and cimetidine.

V Nosálová1, M Petríková, R Nosál.   

Abstract

Gastric mucosal damage caused by the administration of ulcerogenic agents resulted in different changes in lipid peroxidation. An increase in malondialdehyde level was observed after ethanol exposure, whereas suppression of lipid peroxidation occurred after dosing with indomethacin. Changes in lipid peroxides associated with ethanol- but not indomethacin-induced injury were prevented by pretreatment with pentacaine and cimetidine.

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Year:  1989        PMID: 2750588     DOI: 10.1007/bf02222227

Source DB:  PubMed          Journal:  Agents Actions        ISSN: 0065-4299


  9 in total

1.  Simple, sensitive fluorimetric assay for malondialdehyde production by blood platelets.

Authors:  R M McMillan; D E MacIntyre; J L Gordon
Journal:  Thromb Res       Date:  1977-09       Impact factor: 3.944

2.  Local anesthetics, chlorpromazine and propranolol inhibit stimulus-activation of phospholipase A2 in human platelets.

Authors:  J Y Vanderhoek; M B Feinstein
Journal:  Mol Pharmacol       Date:  1979-07       Impact factor: 4.436

Review 3.  Biology of disease: free radicals and tissue injury.

Authors:  B A Freeman; J D Crapo
Journal:  Lab Invest       Date:  1982-11       Impact factor: 5.662

4.  A simplification of the protein assay method of Lowry et al. which is more generally applicable.

Authors:  G L Peterson
Journal:  Anal Biochem       Date:  1977-12       Impact factor: 3.365

5.  Effect of antiperoxidative drugs on gastric damage induced by ethanol in rats.

Authors:  T Mizui; H Sato; F Hirose; M Doteuchi
Journal:  Life Sci       Date:  1987-08-10       Impact factor: 5.037

6.  Lipid peroxidation: a possible role in gastric damage induced by ethanol in rats.

Authors:  T Mizui; M Doteuchi
Journal:  Life Sci       Date:  1986-06-09       Impact factor: 5.037

7.  Free radicals and lipid peroxidation in ethanol- or aspirin-induced gastric mucosal injury.

Authors:  G Pihan; C Regillo; S Szabo
Journal:  Dig Dis Sci       Date:  1987-12       Impact factor: 3.199

8.  Role of oxygen radicals in ischemia-induced lesions in the cat stomach.

Authors:  M A Perry; S Wadhwa; D A Parks; W Pickard; D N Granger
Journal:  Gastroenterology       Date:  1986-02       Impact factor: 22.682

9.  Superoxide radicals in feline intestinal ischemia.

Authors:  D N Granger; G Rutili; J M McCord
Journal:  Gastroenterology       Date:  1981-07       Impact factor: 22.682

  9 in total

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