Literature DB >> 27501101

Introduction to Department of Defense Research on Burn Pits, Biomarkers, and Health Outcomes Related to Deployment in Iraq and Afghanistan.

Col Timothy M Mallon1, Maj Patricia Rohrbeck, Maj Kevin M Haines, Dean P Jones, Mark Utell, Philip K Hopke, Richard P Phipps, Douglas I Walker, Thomas Thatcher, Collynn F Woeller, Coleen P Baird, Harvey B Pollard, Clifton L Dalgard, Joel C Gaydos.   

Abstract

OBJECTIVE: This paper provides an overview of our study that was designed to assess the health impact of environmental exposures to open pit burning in deployed troops.
METHODS: The rationale for the study and the structure of the research plan was laid out. An overview of each article in the supplement was provided. The cohort of deployed Service members was assessed for airborne exposure, relevant biomarkers, and health outcomes following deployment to Balad, Iraq, and/or Bagram, Afghanistan.
RESULTS: Polycyclic aromatic hydrocarbon (PAH) exposures were elevated, and serum biomarkers were statistically different postdeployment. Associations were noted between PAHs and dioxins and microRNAs. Some health outcomes were evident in deployers compared with nondeployers.
CONCLUSIONS: Future research will examine the associations between demographic variables, smoking status, biomarker levels, and related health outcomes.

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Year:  2016        PMID: 27501101     DOI: 10.1097/JOM.0000000000000775

Source DB:  PubMed          Journal:  J Occup Environ Med        ISSN: 1076-2752            Impact factor:   2.162


  11 in total

1.  Metabolome-Wide Association Study of Deployment to Balad, Iraq or Bagram, Afghanistan.

Authors:  Young-Mi Go; Matthew R Smith; Douglas I Walker; Karan Uppal; Patricia Rohrbeck; Pamela L Krahl; Philip K Hopke; Mark J Utell; Timothy M Mallon; Dean P Jones
Journal:  J Occup Environ Med       Date:  2019-12       Impact factor: 2.162

2.  Machine Learning Approach for Predicting Past Environmental Exposures From Molecular Profiling of Post-Exposure Human Serum Samples.

Authors:  Atif Khan; Thomas H Thatcher; Collynn F Woeller; Patricia J Sime; Richard P Phipps; Philip K Hopke; Mark J Utell; Pamela L Krahl; Timothy M Mallon; Juilee Thakar
Journal:  J Occup Environ Med       Date:  2019-12       Impact factor: 2.162

3.  Analysis of Postdeployment Serum Samples Identifies Potential Biomarkers of Exposure to Burn Pits and Other Environmental Hazards.

Authors:  Thomas H Thatcher; Collynn F Woeller; Juilee Thakar; Atif Khan; Philip K Hopke; Matthew Ryan Smith; Karan Uppal; Douglas I Walker; Young-Mi Go; Dean P Jones; Pamela L Krahl; Timothy M Mallon; Patricia J Sime; Richard P Phipps; Mark J Utell
Journal:  J Occup Environ Med       Date:  2019-12       Impact factor: 2.162

4.  Integrative Network Analysis Linking Clinical Outcomes With Environmental Exposures and Molecular Variations in Service Personnel Deployed to Balad and Bagram.

Authors:  Juilee Thakar; Thomas H Thatcher; Matthew Ryan Smith; Collynn F Woeller; Douglas I Walker; Mark J Utell; Philip K Hopke; Timothy M Mallon; Pamela L Krahl; Patricia Rohrbeck; Young-Mi Go; Dean P Jones; Karan Uppal
Journal:  J Occup Environ Med       Date:  2019-12       Impact factor: 2.162

5.  Exposure to Heptachlorodibenzo-p-dioxin (HpCDD) Regulates microRNA Expression in Human Lung Fibroblasts.

Authors:  Collynn F Woeller; Thomas H Thatcher; Juilee Thakar; Adam Cornwell; Matthew R Smith; Dean P Jones; Philip K Hopke; Patricia J Sime; Pamela Krahl; Timothy M Mallon; Richard P Phipps; Mark J Utell
Journal:  J Occup Environ Med       Date:  2019-12       Impact factor: 2.162

6.  Metabolic Pathways and Networks Associated With Tobacco Use in Military Personnel.

Authors:  Dean P Jones; Douglas I Walker; Karan Uppal; Patricia Rohrbeck; Col Timothy M Mallon; Young-Mi Go
Journal:  J Occup Environ Med       Date:  2016-08       Impact factor: 2.162

7.  Deployment-Associated Exposure Surveillance With High-Resolution Metabolomics.

Authors:  Douglas I Walker; Col Timothy M Mallon; Philip K Hopke; Karan Uppal; Young-Mi Go; Patricia Rohrbeck; Kurt D Pennell; Dean P Jones
Journal:  J Occup Environ Med       Date:  2016-08       Impact factor: 2.162

8.  Respiratory Health after Military Service in Southwest Asia and Afghanistan. An Official American Thoracic Society Workshop Report.

Authors:  Eric Garshick; Joseph H Abraham; Coleen P Baird; Paul Ciminera; Gregory P Downey; Michael J Falvo; Jaime E Hart; David A Jackson; Michael Jerrett; Ware Kuschner; Drew A Helmer; Kirk D Jones; Silpa D Krefft; Timothy Mallon; Robert F Miller; Michael J Morris; Susan P Proctor; Carrie A Redlich; Cecile S Rose; Rudolph P Rull; Johannes Saers; Aaron I Schneiderman; Nicholas L Smith; Panayiotis Yiallouros; Paul D Blanc
Journal:  Ann Am Thorac Soc       Date:  2019-08

9.  Chemistry, lung toxicity and mutagenicity of burn pit smoke-related particulate matter.

Authors:  Yong Ho Kim; Sarah H Warren; Ingeborg Kooter; Wanda C Williams; Ingrid J George; Samuel A Vance; Michael D Hays; Mark A Higuchi; Stephen H Gavett; David M DeMarini; Ilona Jaspers; M Ian Gilmour
Journal:  Part Fibre Toxicol       Date:  2021-12-16       Impact factor: 9.400

10.  A Detoxification Intervention for Gulf War Illness: A Pilot Randomized Controlled Trial.

Authors:  Kathleen Kerr; Gayle Morse; Donald Graves; Fei Zuo; Alain Lipowicz; David O Carpenter
Journal:  Int J Environ Res Public Health       Date:  2019-10-28       Impact factor: 3.390

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