Literature DB >> 27499448

Docosahexaenoic acid supplementation (DHA) and the return on investment for pregnancy outcomes.

T I Shireman1, E H Kerling2, B J Gajewski3, J Colombo4, S E Carlson5.   

Abstract

The Kansas University DHA Outcomes Study (KUDOS) found a significant reduction in early preterm births with a supplement of 600mg DHA per day compared to placebo. The objective of this analysis was to determine if hospital costs differed between groups. We applied a post-hoc cost analysis of the delivery hospitalization and all hospitalizations in the following year to 197 mother-infant dyads who delivered at Kansas University Hospital. Hospital cost saving of DHA supplementation amounted to $1678 per infant. Even after adjusting for the estimated cost of providing 600mg/d DHA for 26 weeks ($166.48) and a slightly higher maternal care cost ($26) in the DHA group, the net saving per dyad was $1484. Extrapolating this to the nearly 4 million US deliveries per year suggests universal supplementation with 600mg/d during the last 2 trimesters of pregnancy could save the US health care system up to USD 6 billion.
Copyright © 2016 Elsevier Ltd. All rights reserved.

Entities:  

Keywords:  Docosahexaenoic acid; Hospital cost; Pregnancy; Preterm birth

Mesh:

Substances:

Year:  2016        PMID: 27499448      PMCID: PMC4978141          DOI: 10.1016/j.plefa.2016.05.008

Source DB:  PubMed          Journal:  Prostaglandins Leukot Essent Fatty Acids        ISSN: 0952-3278            Impact factor:   4.006


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Authors:  Susan E Carlson; John Colombo; Byron J Gajewski; Kathleen M Gustafson; David Mundy; John Yeast; Michael K Georgieff; Lisa A Markley; Elizabeth H Kerling; D Jill Shaddy
Journal:  Am J Clin Nutr       Date:  2013-02-20       Impact factor: 7.045

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1.  Predicting the effect of maternal docosahexaenoic acid (DHA) supplementation to reduce early preterm birth in Australia and the United States using results of within country randomized controlled trials.

Authors:  L N Yelland; B J Gajewski; J Colombo; R A Gibson; M Makrides; S E Carlson
Journal:  Prostaglandins Leukot Essent Fatty Acids       Date:  2016-08-17       Impact factor: 4.006

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