Literature DB >> 26432510

Analysis of hospital cost outcome of DHA-rich fish-oil supplementation in pregnancy: Evidence from a randomized controlled trial.

Sharmina Ahmed1, Maria Makrides2, Nicholas Sim3, Andy McPhee4, Julie Quinlivan5, Robert Gibson6, Wendy Umberger7.   

Abstract

OBJECTIVE: Recent research emphasized the nutritional benefits of omega-3 long chain polyunsaturated fatty acids (LCPUFAs) during pregnancy. Based on a double-blind randomised controlled trial named "DHA to Optimize Mother and Infant Outcome" (DOMInO), we examined how omega 3 DHA supplementation during pregnancy may affect pregnancy related in-patient hospital costs.
METHOD: We conducted an econometric analysis based on ordinary least square and quantile regressions with bootstrapped standard errors. Using these approaches, we also examined whether smoking, drinking, maternal age and BMI could influence the effect of DHA supplementation during pregnancy on hospital costs.
RESULTS: Our regressions showed that in-patient hospital costs could decrease by AUD92 (P<0.05) on average per singleton pregnancy when DHA supplements were consumed during pregnancy. Our regression results also showed that the cost savings to the Australian public hospital system could be between AUD15 - AUD51 million / year.
CONCLUSION: Given that a simple intervention like DHA-rich fish-oil supplementation could generate savings to the public, it may be worthwhile from a policy perspective to encourage DHA supplementation among pregnant women.
Copyright © 2015 Elsevier Ltd. All rights reserved.

Entities:  

Keywords:  Australia; DHA-rich fish oil supplementation.; Health economics evaluation; Hospital cost analysis; Pregnancy and birth outcomes; Randomized trial

Mesh:

Substances:

Year:  2015        PMID: 26432510     DOI: 10.1016/j.plefa.2015.08.002

Source DB:  PubMed          Journal:  Prostaglandins Leukot Essent Fatty Acids        ISSN: 0952-3278            Impact factor:   4.006


  4 in total

1.  Predicting the effect of maternal docosahexaenoic acid (DHA) supplementation to reduce early preterm birth in Australia and the United States using results of within country randomized controlled trials.

Authors:  L N Yelland; B J Gajewski; J Colombo; R A Gibson; M Makrides; S E Carlson
Journal:  Prostaglandins Leukot Essent Fatty Acids       Date:  2016-08-17       Impact factor: 4.006

2.  Docosahexaenoic acid supplementation (DHA) and the return on investment for pregnancy outcomes.

Authors:  T I Shireman; E H Kerling; B J Gajewski; J Colombo; S E Carlson
Journal:  Prostaglandins Leukot Essent Fatty Acids       Date:  2016-05-13       Impact factor: 4.006

3.  Breast milk DHA levels may increase after informing women: a community-based cohort study from South Dakota USA.

Authors:  Brian A Juber; Kristina Harris Jackson; Kristopher B Johnson; William S Harris; Michelle L Baack
Journal:  Int Breastfeed J       Date:  2017-01-28       Impact factor: 3.461

4.  Omega-3 fatty acid addition during pregnancy.

Authors:  Philippa Middleton; Judith C Gomersall; Jacqueline F Gould; Emily Shepherd; Sjurdur F Olsen; Maria Makrides
Journal:  Cochrane Database Syst Rev       Date:  2018-11-15
  4 in total

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