Literature DB >> 27493696

Synthesis of a series of novel 2,5-disubstituted-1,3,4-oxadiazole derivatives as potential antioxidant and antibacterial agents.

M Aruna Sindhe1, Yadav D Bodke1, R Kenchappa1, Sandeep Telkar2, A Chandrashekar1.   

Abstract

A series of novel 2,5-disubstituted-1,3,4-oxadiazole derivatives were synthesized and screened for their antimicrobial and antioxidant activities. The assay indicated that compounds 3c, 3d, and 3i exhibited comparable antibacterial and antioxidant activity with first-line drugs. The structure activity relationship and molecular docking study of the synthesized compounds are also reported.

Entities:  

Keywords:  1,3,4-Oxadiazole; Antimicrobial; Antioxidant; Molecular docking

Year:  2016        PMID： 27493696      PMCID： PMC4958064          DOI： 10.1007/s12154-016-0153-9

Source DB:  PubMed          Journal:  J Chem Biol        ISSN： 1864-6158


  26 in total

1.  Synthesis and antimalarial activity of novel chiral and achiral benzenesulfonamides bearing 1, 3, 4-oxadiazole moieties.

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Journal:  J Enzyme Inhib Med Chem       Date:  2007-06       Impact factor: 5.051

2.  Synthesis and antiviral activity of 2-substituted methylthio-5-(4-amino-2-methylpyrimidin-5-yl)-1,3,4-oxadiazole derivatives.

Authors:  Wenneng Wu; Qin Chen; Anqi Tai; Guangqi Jiang; Guiping Ouyang
Journal:  Bioorg Med Chem Lett       Date:  2015-03-07       Impact factor: 2.823

Review 3.  Antimicrobial resistance and virulence: a successful or deleterious association in the bacterial world?

Authors:  Alejandro Beceiro; María Tomás; Germán Bou
Journal:  Clin Microbiol Rev       Date:  2013-04       Impact factor: 26.132

4.  Design, Synthesis, and Antitumor Activity of Novel 5-Pyridyl-1,3,4-oxadiazole Derivatives against the Breast Cancer Cell Line MCF-7.

Authors:  Nadia Abdalla Khalil; Aliaa Moh Kamal; Soha Hussein Emam
Journal:  Biol Pharm Bull       Date:  2015       Impact factor: 2.233

Review 5.  Reactive oxygen species in cell signaling.

Authors:  V J Thannickal; B L Fanburg
Journal:  Am J Physiol Lung Cell Mol Physiol       Date:  2000-12       Impact factor: 5.464

6.  Anti-HIV activity of new substituted 1,3,4-oxadiazole derivatives and their acyclic nucleoside analogues.

Authors:  Wael A El-Sayed; Farag A El-Essawy; Omar M Ali; Barsis S Nasr; Mohamed M Abdalla; Adel A-H Abdel-Rahman
Journal:  Z Naturforsch C J Biosci       Date:  2009 Nov-Dec

7.  Effects of the Cellcultured Acanthopanax senticosus Extract on Antioxidative Defense System and Membrane Fluidity in the Liver of Type 2 Diabetes Mouse.

Authors:  Jung-Hee Hong; Youn-Soo Cha; Soon-Jae Rhee
Journal:  J Clin Biochem Nutr       Date:  2009-06-30       Impact factor: 3.114

Review 8.  Reactive oxygen species: metabolism, oxidative stress, and signal transduction.

Authors:  Klaus Apel; Heribert Hirt
Journal:  Annu Rev Plant Biol       Date:  2004       Impact factor: 26.379

Review 9.  1,3,4-oxadiazole derivatives as potential biological agents.

Authors:  Juan Sun; Jigar A Makawana; Hai-Liang Zhu
Journal:  Mini Rev Med Chem       Date:  2013-10       Impact factor: 3.862

Review 10.  Comparative genomics and host resistance against infectious diseases.

Authors:  S T Qureshi; E Skamene; D Malo
Journal:  Emerg Infect Dis       Date:  1999 Jan-Feb       Impact factor: 6.883
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  4 in total

1.  Antifungal and anthelmintic activity of novel benzofuran derivatives containing thiazolo benzimidazole nucleus: an in vitro evaluation.

Authors:  R Kenchappa; Yadav D Bodke; Sandeep Telkar; M Aruna Sindhe
Journal:  J Chem Biol       Date:  2016-09-08

2.  Inhibitors of glucosamine-6-phosphate synthase as potential antimicrobials or antidiabetics - synthesis and properties.

Authors:  Joanna Stefaniak; Michał G Nowak; Marek Wojciechowski; Sławomir Milewski; Andrzej S Skwarecki
Journal:  J Enzyme Inhib Med Chem       Date:  2022-12       Impact factor: 5.756

Review 3.  Antimicrobial Activity of 1,3,4-Oxadiazole Derivatives.

Authors:  Teresa Glomb; Piotr Świątek
Journal:  Int J Mol Sci       Date:  2021-06-29       Impact factor: 5.923

4.  Combined Electrochemical, Raman Analysis and Machine Learning Assessments of the Inhibitive Properties of an 1,3,4-Oxadiazole-2-Thiol Derivative against Carbon Steel Corrosion in HCl Solution.

Authors:  Simona Varvara; Camelia Berghian-Grosan; Gianina Damian; Maria Popa; Florin Popa
Journal:  Materials (Basel)       Date:  2022-03-17       Impact factor: 3.623
  4 in total

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