Literature DB >> 27488934

The CelluTome epidermal graft-harvesting system: a patient-reported outcome measure and cost evaluation study.

Oliver J Smith1, Sarah-Jayne Edmondson1, Nicki Bystrzonowski1, Nadine Hachach-Haram1, Muholan Kanapathy1,2, Toby Richards1,2, Ash Mosahebi1,2.   

Abstract

Conventional split skin grafts (SSG) require anaesthesia, specialist equipment and can have high donor site (DS) morbidity. The CelluTome epidermal graft-harvesting device is a novel alternative, providing pain-free epidermal skin grafts (ESG) in the outpatient setting, with projected minimal DS trauma and improved patient satisfaction. This study aimed to compare ESG with SSG by evaluating patient-related outcome measures (PROMs) and the cost implications of both. Twenty patients answered a graft satisfaction questionnaire that evaluated: donor/graft site noticeability, aesthetic concerns, adverse problems and patient satisfaction. Cost/patient was calculated based on total operative expenses and five clinic follow-ups. In 100% of the ESG cases, there were no DS noticeability or adverse problems compared to 25% in the SSG group. Complete satisfaction with DS appearance was observed in 100% of the ESG cases (50% SSG). Noticeability, adverse problems and overall satisfaction were significantly better in ESG cases (P < 0.05). Graft site parameters were comparable with similar healing outcomes. The cost per patient for ESG was £431 and £1489 for SSG, with an annual saving of £126 960 based on 10 grafts/month. For the right patient, CelluTome provides comparable wound healing, with reduced DS morbidity and higher patient satisfaction.
© 2016 Medicalhelplines.com Inc and John Wiley & Sons Ltd.

Entities:  

Keywords:  CelluTome; Cost analysis; Epidermal skin grafting; Patient-recorded outcome measures; Split skin grafting

Mesh:

Year:  2016        PMID: 27488934      PMCID: PMC7950070          DOI: 10.1111/iwj.12644

Source DB:  PubMed          Journal:  Int Wound J        ISSN: 1742-4801            Impact factor:   3.315


  12 in total

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Journal:  Lancet       Date:  1964-06-27       Impact factor: 79.321

2.  Prevention of amputation caused by rheumatic diseases following a novel therapy of exposing bone marrow, occlusive dressing and subsequent epidermal grafting.

Authors:  Y Yamaguchi; Y Sumikawa; S Yoshida; T Kubo; K Yoshikawa; S Itami
Journal:  Br J Dermatol       Date:  2005-04       Impact factor: 9.302

3.  The use of epidermal grafting for the management of acute wounds in the outpatient setting.

Authors:  Nadine Hachach-Haram; Nicola Bystrzonowski; Muholan Kanapathy; Sarah-Jayne Edmondson; Lucy Twyman; Toby Richards; Afshin Mosahebi
Journal:  J Plast Reconstr Aesthet Surg       Date:  2015-05-12       Impact factor: 2.740

4.  Epidermal grafting using a novel suction blister-harvesting system for the treatment of pyoderma gangrenosum.

Authors:  Nicholas A Richmond; Sonia A Lamel; Liza R Braun; Alejandra C Vivas; Thomas Serena; Robert S Kirsner
Journal:  JAMA Dermatol       Date:  2014-09       Impact factor: 10.282

5.  Epidermal grafting. An original technique and its application in achromic and granulating areas.

Authors:  R Falabella
Journal:  Arch Dermatol       Date:  1971-12

6.  Use of a novel epidermal harvesting system in resource-poor countries.

Authors:  Thomas Serena; Adler Francius; Cristin Taylor; John MacDonald
Journal:  Adv Skin Wound Care       Date:  2015-03       Impact factor: 2.347

7.  Suction blister transplantation for leg ulcers.

Authors:  B Hentzer; T Kobayasi
Journal:  Acta Derm Venereol       Date:  1975       Impact factor: 4.437

8.  Autologous suction blister grafting for chronic leg ulcers.

Authors:  U Costanzo; M Streit; L R Braathen
Journal:  J Eur Acad Dermatol Venereol       Date:  2008-01       Impact factor: 6.166

9.  Rapid healing of intractable diabetic foot ulcers with exposed bones following a novel therapy of exposing bone marrow cells and then grafting epidermal sheets.

Authors:  Y Yamaguchi; S Yoshida; Y Sumikawa; T Kubo; K Hosokawa; K Ozawa; V J Hearing; K Yoshikawa; S Itami
Journal:  Br J Dermatol       Date:  2004-11       Impact factor: 9.302

10.  The psychological impact of split-thickness skin grafts.

Authors:  E L E Hansen; A Clarke; N Austin-Parsons; P E M Butler
Journal:  J Wound Care       Date:  2012-10       Impact factor: 2.072

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  7 in total

1.  Use of Cellutome for the healing of venous or mixed ulcers.

Authors:  Blandine Vinceneux Talvande; Priscille Carvalho Lallement; Gilles Safa; Julie Journet Tollhupp; Jean-Paul Lembelembe; Sophie Blaise; Hervé Maillard
Journal:  Int Wound J       Date:  2018-08-09       Impact factor: 3.315

2.  Systematic review of the efficacy of fat grafting and platelet-rich plasma for wound healing.

Authors:  Oliver J Smith; Muholan Kanapathy; Ankur Khajuria; Max Prokopenko; Nadine Hachach-Haram; Haroon Mann; Ash Mosahebi
Journal:  Int Wound J       Date:  2018-05-09       Impact factor: 3.315

3.  Comparative study on the donor site aesthetic outcome between epidermal graft and split-thickness skin graft.

Authors:  Muholan Kanapathy; Afshin Mosahebi
Journal:  Int Wound J       Date:  2018-11-15       Impact factor: 3.315

Review 4.  Surgical Treatment of Vitiligo.

Authors:  Alicja Frączek; Marta Kasprowicz-Furmańczyk; Waldemar Placek; Agnieszka Owczarczyk-Saczonek
Journal:  Int J Environ Res Public Health       Date:  2022-04-15       Impact factor: 4.614

5.  A Case Series of Complex Recalcitrant Wounds Treated with Epidermal Grafts Harvested from an Automated Device.

Authors:  Stephen S Cai; Arvind U Gowda; Karan Chopra; Rachel Waldman; Ronald P Silverman; Yvonne M Rasko
Journal:  Cureus       Date:  2016-10-30

6.  A comparative study of suction blister epidermal grafting and automated blister epidermal micrograft in stable vitiligo.

Authors:  Pei-Rong Gao; Chi-Hui Wang; Yu-Jr Lin; Yu-Huei Huang; Ya-Ching Chang; Wen-Hung Chung; Chau Yee Ng
Journal:  Sci Rep       Date:  2022-01-10       Impact factor: 4.379

Review 7.  Skin grafting treatment of adolescent lower limb avulsion injury.

Authors:  Liu Yang; Jiachao Guo; Jinpeng He; Jingfan Shao
Journal:  Front Surg       Date:  2022-09-15
  7 in total

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