Literature DB >> 27488585

A Review on Pharmacological Properties of Coumarins.

Devulapally Srikrishna1, Chandraiah Godugu2, Pramod Kumar Dubey1.   

Abstract

The coumarin (benzopyran-2-one, or chromen-2-one) ring system, present in many natural products, displays diverse pharmacological properties. It has attracted the attention of chemists and medicinal chemists for decades. Many molecules based on the coumarin ring system have been described utilizing innovative synthetic methods. These synthetic routes have led to interesting analogues of coumarins which possess pharmacological activities like anti-HIV, antimicrobial, antiinflammatory, anticancer, anti-TB, anticonvulsant and MAO inhibitory properties. Details of these studies, correlating structure with biological activity are described in this review. Copyright© Bentham Science Publishers; For any queries, please email at epub@benthamscience.org.

Entities:  

Keywords:  Anticancer; MAO inhibitory; anti-inflammatory; anticonvulsant; antimicrobial; antioxidant; coumarin; pharmacologicalzzm321990properties

Mesh：

Substances：

Year:  2018        PMID： 27488585     DOI： 10.2174/1389557516666160801094919

Source DB:  PubMed          Journal:  Mini Rev Med Chem        ISSN： 1389-5575            Impact factor:   3.862


  22 in total

1.  Characterisation, pathogenicity and hydrolytic enzyme profiling of selected Fusarium species and their inhibition by novel coumarins.

Authors:  Ayodeji Amobonye; Prashant Bhagwat; Divona Ranjith; Viresh Mohanlall; Santhosh Pillai
Journal:  Arch Microbiol       Date:  2021-04-28       Impact factor: 2.552

Review 2.  An Overview of Coumarin as a Versatile and Readily Accessible Scaffold with Broad-Ranging Biological Activities.

Authors:  Francesca Annunziata; Cecilia Pinna; Sabrina Dallavalle; Lucia Tamborini; Andrea Pinto
Journal:  Int J Mol Sci       Date:  2020-06-29       Impact factor: 5.923

Review 3.  Nutraceutical and Ethnopharmacological Properties of Vangueria infausta subsp. infausta.

Authors:  Alfred Maroyi
Journal:  Molecules       Date:  2018-05-04       Impact factor: 4.411

4.  Crystal structure and Hirshfeld surface analysis of 2-[(2-oxo-2H-chromen-4-yl)-oxy]acetic acid dimethyl sulfoxide monosolvate.

Authors:  S Syed Abuthahir; M NizamMohideen; V Viswanathan; M Govindhan; K Subramanian
Journal:  Acta Crystallogr E Crystallogr Commun       Date:  2019-07-09

5.  Coumarin-Tagged Dinuclear Trithiolato-Bridged Ruthenium(II)⋅Arene Complexes: Photophysical Properties and Antiparasitic Activity.

Authors:  Oksana Desiatkina; Emilia Păunescu; Martin Mösching; Nicoleta Anghel; Ghalia Boubaker; Yosra Amdouni; Andrew Hemphill; Julien Furrer
Journal:  Chembiochem       Date:  2020-06-16       Impact factor: 3.164

Review 6.  Current and Promising Antivirals Against Chikungunya Virus.

Authors:  Friederike I L Hucke; Joachim J Bugert
Journal:  Front Public Health       Date:  2020-12-15

7.  Chiral Tertiary Amine Catalyzed Asymmetric [4 + 2] Cyclization of 3-Aroylcoumarines with 2,3-Butadienoate.

Authors:  Jun-Lin Li; Xiao-Hui Wang; Jun-Chao Sun; Yi-Yuan Peng; Cong-Bin Ji; Xing-Ping Zeng
Journal:  Molecules       Date:  2021-01-18       Impact factor: 4.411

8.  (E)-N'-(1-(7-Hydroxy-2-Oxo-2H-Chromen-3-Yl) Ethylidene) Benzohydrazide, a Novel Synthesized Coumarin, Ameliorates Isoproterenol-Induced Myocardial Infarction in Rats through Attenuating Oxidative Stress, Inflammation, and Apoptosis.

Authors:  Anouar Feriani; Emna Khdhiri; Meriam Tir; Afoua Elmufti; Nizar Tlili; Raouf Hajji; Houcine Ammar; Noureddine Allouche; Souhir Abid; Lakhdar Ghazouani; Kais Mnafgui
Journal:  Oxid Med Cell Longev       Date:  2020-03-06       Impact factor: 6.543

Review 9.  Efficacy and Mechanism of Traditional Medicinal Plants and Bioactive Compounds against Clinically Important Pathogens.

Authors:  Suresh Mickymaray
Journal:  Antibiotics (Basel)       Date:  2019-12-09

10.  4-Hydroxy-7-Methoxycoumarin Inhibits Inflammation in LPS-activated RAW264.7 Macrophages by Suppressing NF-κB and MAPK Activation.

Authors:  Jin Kyu Kang; Chang-Gu Hyun
Journal:  Molecules       Date:  2020-09-26       Impact factor: 4.411
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