Literature DB >> 27475847

Role of C1q complement fixing antibody assay in therapeutic plasma exchange management of pediatric cardiac antibody mediated rejection.

Oluwatoyosi A Onwuemene1, Deneen M Heath2, Carol Hartman2, Edward C C Wong3.   

Abstract

Pediatric cardiac transplant patients with antibody-mediated rejection (AMR) often undergo therapeutic plasma exchange (TPE) to remove pathologic donor specific antibodies (DSA). In cases where DSA persist, it is unclear how long TPE should be continued. We report a case of a 17-year-old cardiac transplant patient with AMR where use of a C1q complement fixing antibody assay helped guide TPE cessation. This report adds to the existing literature that highlights the potential clinical significance of C1q antibodies in AMR management.
© 2016 Wiley Periodicals, Inc.

Entities:  

Keywords:  HLA antibodies; acute rejection; donor specific antibodies; heart transplantation; plasmapheresis

Mesh：

Substances：

Year:  2016        PMID： 27475847      PMCID： PMC6852646          DOI： 10.1002/jca.21488

Source DB:  PubMed          Journal:  J Clin Apher        ISSN： 0733-2459            Impact factor:   2.821


  11 in total

1.  C1q Binding Activity of De Novo Donor-specific HLA Antibodies in Renal Transplant Recipients With and Without Antibody-mediated Rejection.

Authors:  Maggie Yell; Brenda L Muth; Dixon B Kaufman; Arjang Djamali; Thomas M Ellis
Journal:  Transplantation       Date:  2015-06       Impact factor: 4.939

2.  Guidelines on the use of therapeutic apheresis in clinical practice-evidence-based approach from the Writing Committee of the American Society for Apheresis: the sixth special issue.

Authors:  Joseph Schwartz; Jeffrey L Winters; Anand Padmanabhan; Rasheed A Balogun; Meghan Delaney; Michael L Linenberger; Zbigniew M Szczepiorkowski; Mark E Williams; Yanyun Wu; Beth H Shaz
Journal:  J Clin Apher       Date:  2013-07       Impact factor: 2.821

3.  Antibody-mediated rejection in cardiac transplantation: emerging knowledge in diagnosis and management: a scientific statement from the American Heart Association.

Authors:  Monica M Colvin; Jennifer L Cook; Patricia Chang; Gary Francis; Daphne T Hsu; Michael S Kiernan; Jon A Kobashigawa; JoAnn Lindenfeld; Sofia Carolina Masri; Dylan Miller; John O'Connell; E Rene Rodriguez; Bruce Rosengard; Sally Self; Connie White-Williams; Adriana Zeevi
Journal:  Circulation       Date:  2015-04-02       Impact factor: 29.690

4.  Heart.

Authors:  M Colvin; J M Smith; M A Skeans; L B Edwards; E R Callahan; J J Snyder; A K Israni; B L Kasiske
Journal:  Am J Transplant       Date:  2016-01       Impact factor: 8.086

5.  Persistent strong anti-HLA antibody at high titer is complement binding and associated with increased risk of antibody-mediated rejection in heart transplant recipients.

Authors:  Adriana Zeevi; John Lunz; Brian Feingold; Michael Shullo; Christian Bermudez; Jeffery Teuteberg; Steven Webber
Journal:  J Heart Lung Transplant       Date:  2012-11-09       Impact factor: 10.247

6.  Clinical usefulness of a novel C1q assay to detect immunoglobulin G antibodies capable of fixing complement in sensitized pediatric heart transplant patients.

Authors:  Clifford Chin; Ge Chen; Flavia Sequeria; Gerald Berry; Stephanie Siehr; Daniel Bernstein; David Rosenthal; Olaf Reinhartz; Dolly Tyan
Journal:  J Heart Lung Transplant       Date:  2010-10-15       Impact factor: 10.247

7.  Rapid reduction in donor-specific anti-human leukocyte antigen antibodies and reversal of antibody-mediated rejection with bortezomib in pediatric heart transplant patients.

Authors:  William Robert Morrow; Elizabeth A Frazier; William T Mahle; Terry O Harville; Sherry E Pye; Kenneth R Knecht; Emily L Howard; R Neal Smith; Robert L Saylors; Xiomara Garcia; Robert D B Jaquiss; E Steve Woodle
Journal:  Transplantation       Date:  2012-02-15       Impact factor: 4.939

8.  Impact of IgG3 subclass and C1q-fixing donor-specific HLA alloantibodies on rejection and survival in liver transplantation.

Authors:  J G O'Leary; H Kaneku; N Banuelos; L W Jennings; G B Klintmalm; P I Terasaki
Journal:  Am J Transplant       Date:  2015-03-13       Impact factor: 8.086

9.  Association of Kidney Graft Loss With De Novo Produced Donor-Specific and Non-Donor-Specific HLA Antibodies Detected by Single Antigen Testing.

Authors:  Caner Süsal; Daniel Wettstein; Bernd Döhler; Christian Morath; Andrea Ruhenstroth; Sabine Scherer; Thuong H Tran; Petra Gombos; Peter Schemmer; Eric Wagner; Thomas Fehr; Stela Živčić-Ćosić; Sanja Balen; Rolf Weimer; Antonij Slavcev; Claudia Bösmüller; Douglas J Norman; Martin Zeier; Gerhard Opelz
Journal:  Transplantation       Date:  2015-09       Impact factor: 4.939

10.  Measurement of donor-specific HLA antibodies following plasma exchange therapy predicts clinical outcome in pediatric heart and lung transplant recipients with antibody-mediated rejection.

Authors:  Ronald Jackups; Charles Canter; Stuart C Sweet; T Mohanakumar; Gerald P Morris
Journal:  J Clin Apher       Date:  2013-02-21       Impact factor: 2.821
View more
  1 in total

1.  Indications for and outcomes of therapeutic plasma exchange after cardiac transplantation: A single center retrospective study.

Authors:  Oluwatoyosi A Onwuemene; Steven C Grambow; Chetan B Patel; Robert J Mentz; Carmelo A Milano; Joseph G Rogers; Ara D Metjian; Gowthami M Arepally; Thomas L Ortel
Journal:  J Clin Apher       Date:  2018-03-10       Impact factor: 2.821
  1 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.