Literature DB >> 27471058

Family-Focused Therapy for Bipolar Disorder: Reflections on 30 Years of Research.

David J Miklowitz1, Bowen Chung2.   

Abstract

Family-focused therapy (FFT) is an evidence-based intervention for adults and children with bipolar disorder (BD) and their caregivers, usually given in conjunction with pharmacotherapy after an illness episode. The treatment consists of conjoint sessions of psychoeducation regarding bipolar illness, communication enhancement training, and problem-solving skills training. This paper summarizes over 30 years of research on FFT and family processes in BD. Across eight randomized controlled trials with adults and adolescents with BD, FFT and mood-stabilizing medications have been found to hasten recovery from mood episodes, reduce recurrences, and reduce levels of symptom severity compared to briefer forms of psychoeducation and medications over 1-2 years. Several studies indicate that the effects of FFT on symptom improvement are greater among patients with high-expressed emotion relatives. New research focuses on FFT as an early intervention for youth at risk for BD, neuroimaging as a means of evaluating treatment mechanisms, and progress in implementing FFT in community mental health settings.
© 2016 Family Process Institute.

Entities:  

Keywords:  Bipolar Disorder; Expressed Emotion; FFT; Family Interaction; Family-Focused Therapy; Functional Magnetic Resonance Imaging; Psychosis; emoción expresada; interacciones familiares; psicosis; resonancia magnética funcional; terapia centrada en la familia; trastorno bipolar; 功能性核磁共振; 家庭互动; 表达情感; 躁郁症; 重性精神病

Mesh:

Substances:

Year:  2016        PMID: 27471058      PMCID: PMC5922774          DOI: 10.1111/famp.12237

Source DB:  PubMed          Journal:  Fam Process        ISSN: 0014-7370


  44 in total

1.  Expressed emotion and communication deviance in the families of schizophrenics.

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Journal:  J Abnorm Psychol       Date:  1986-02

2.  Influence of family life on the course of schizophrenic disorders: a replication.

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Journal:  Br J Psychiatry       Date:  1972-09       Impact factor: 9.319

3.  Psychosocial treatments for bipolar depression: a 1-year randomized trial from the Systematic Treatment Enhancement Program.

Authors:  David J Miklowitz; Michael W Otto; Ellen Frank; Noreen A Reilly-Harrington; Stephen R Wisniewski; Jane N Kogan; Andrew A Nierenberg; Joseph R Calabrese; Lauren B Marangell; Laszlo Gyulai; Mako Araga; Jodi M Gonzalez; Edwin R Shirley; Michael E Thase; Gary S Sachs
Journal:  Arch Gen Psychiatry       Date:  2007-04

Review 4.  Behavioral family treatment for patients with bipolar affective disorder.

Authors:  D J Miklowitz; M J Goldstein
Journal:  Behav Modif       Date:  1990-10

5.  Bipolar disorder and family communication: effects of a psychoeducational treatment program.

Authors:  T L Simoneau; D J Miklowitz; J A Richards; R Saleem; E L George
Journal:  J Abnorm Psychol       Date:  1999-11

6.  Family transactions and relapse in bipolar disorder.

Authors:  I S Rosenfarb; D J Miklowitz; M J Goldstein; L Harmon; K H Nuechterlein; M M Rea
Journal:  Fam Process       Date:  2001

7.  Family-focused treatment for adolescents with bipolar disorder: results of a 2-year randomized trial.

Authors:  David J Miklowitz; David A Axelson; Boris Birmaher; Elizabeth L George; Dawn O Taylor; Christopher D Schneck; Carol A Beresford; L Miriam Dickinson; W Edward Craighead; David A Brent
Journal:  Arch Gen Psychiatry       Date:  2008-09

8.  Expressed emotion moderates the effects of family-focused treatment for bipolar adolescents.

Authors:  David J Miklowitz; David A Axelson; Elizabeth L George; Dawn O Taylor; Christopher D Schneck; Aimee E Sullivan; L Miriam Dickinson; Boris Birmaher
Journal:  J Am Acad Child Adolesc Psychiatry       Date:  2009-06       Impact factor: 8.829

9.  Interactional correlates of expressed emotion in the families of schizophrenics.

Authors:  D J Miklowitz; M J Goldstein; I R Falloon; J A Doane
Journal:  Br J Psychiatry       Date:  1984-05       Impact factor: 9.319

10.  Psychophysiological responses of schizophrenic patients to high and low expressed emotion relatives: a follow-up study.

Authors:  D Sturgeon; G Turpin; L Kuipers; R Berkowitz; J Leff
Journal:  Br J Psychiatry       Date:  1984-07       Impact factor: 9.319

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  37 in total

1.  Improved Parent-Child Interactions Predict Reduced Internalizing Symptoms Among the Offspring of Parents with Bipolar Disorder Undergoing a Prevention Program: A Proof-of-Concept Study.

Authors:  Lisa Serravalle; Vanessa Iacono; Alexa L Wilson; Mark Anthony Orlando; Virginia Tsekova; Mark A Ellenbogen
Journal:  Res Child Adolesc Psychopathol       Date:  2021-02-05

2.  A Longitudinal Study of Family Functioning in Offspring of Parents Diagnosed With Bipolar Disorder.

Authors:  Amit Shalev; John Merranko; Tina Goldstein; David J Miklowitz; David Axelson; Benjamin I Goldstein; David Brent; Kelly Monk; Mary Beth Hickey; Danella M Hafeman; Dara Sakolsky; Rasim Diler; Boris Birmaher
Journal:  J Am Acad Child Adolesc Psychiatry       Date:  2018-12-19       Impact factor: 8.829

Review 3.  [Psychotherapy for people with bipolar disorders : An overview of evidence-based procedures and new developments].

Authors:  T J Stamm; L-M Sondergeld; G Juckel; M Bauer
Journal:  Nervenarzt       Date:  2018-03       Impact factor: 1.214

4.  The Kindling/Sensitization Model and Early Life Stress.

Authors:  Robert M Post
Journal:  Curr Top Behav Neurosci       Date:  2021

5.  Canadian Network for Mood and Anxiety Treatments (CANMAT) and International Society for Bipolar Disorders (ISBD) 2018 guidelines for the management of patients with bipolar disorder.

Authors:  Lakshmi N Yatham; Sidney H Kennedy; Sagar V Parikh; Ayal Schaffer; David J Bond; Benicio N Frey; Verinder Sharma; Benjamin I Goldstein; Soham Rej; Serge Beaulieu; Martin Alda; Glenda MacQueen; Roumen V Milev; Arun Ravindran; Claire O'Donovan; Diane McIntosh; Raymond W Lam; Gustavo Vazquez; Flavio Kapczinski; Roger S McIntyre; Jan Kozicky; Shigenobu Kanba; Beny Lafer; Trisha Suppes; Joseph R Calabrese; Eduard Vieta; Gin Malhi; Robert M Post; Michael Berk
Journal:  Bipolar Disord       Date:  2018-03-14       Impact factor: 6.744

6.  Perceived Criticism in the Treatment of a High-Risk Adolescent.

Authors:  Jill M Hooley; David J Miklowitz
Journal:  J Clin Psychol       Date:  2017-01-23

7.  Enhancing quality of life among adolescents with bipolar disorder: A randomized trial of two psychosocial interventions.

Authors:  Lisa A O'Donnell; David A Axelson; Robert A Kowatch; Christopher D Schneck; Catherine A Sugar; David J Miklowitz
Journal:  J Affect Disord       Date:  2017-04-28       Impact factor: 4.839

8.  Family communication with teens at clinical high-risk for psychosis or bipolar disorder.

Authors:  Julia M Salinger; Mary P O'Brien; David J Miklowitz; Sarah E Marvin; Tyrone D Cannon
Journal:  J Fam Psychol       Date:  2018-02-01

Review 9.  Evidence-Based Psychotherapies for Bipolar Disorder.

Authors:  Danielle M Novick; Holly A Swartz
Journal:  Focus (Am Psychiatr Publ)       Date:  2019-07-16

10.  Effects of Family-Focused Therapy vs Enhanced Usual Care for Symptomatic Youths at High Risk for Bipolar Disorder: A Randomized Clinical Trial.

Authors:  David J Miklowitz; Christopher D Schneck; Patricia D Walshaw; Manpreet K Singh; Aimee E Sullivan; Robert L Suddath; Marcy Forgey Borlik; Catherine A Sugar; Kiki D Chang
Journal:  JAMA Psychiatry       Date:  2020-05-01       Impact factor: 21.596

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