Literature DB >> 27465885

Patterns of Care and Outcome of Elderly Women Diagnosed With Cervical Cancer in the Developing World.

Angelica Nogueira-Rodrigues1, Andreia Cristina de Melo, Alvaro Henrique Ingles Garces, Eduardo Paulino, Flavia Vieira Guerra Alves, Mariana do Nascimento Vilaça, Laisa Gabrielle Silva, Cristiane Alves Gonçalves, Juliana Chaves Fabrini, Anderson Thiago Vieira Carneiro, Luiz Claudio Santos Thuler.   

Abstract

Scarce data exist about the impact of age in cervical cancer (CC) patients in the developing world. The objective of the current study was to examine the patterns of care and outcome of elderly patients treated in a developing country. Medical records of patients treated from 2006-2009 at the Brazilian National Cancer Institute were reviewed. Patients were divided between women 70 years or older and women younger than 70 years. The χ tests were used and odds ratios were calculated. Survival was examined using the Kaplan-Meier method. Single and multivariate Cox proportional hazards modeling were used. A total of 1482 patients were analyzed: 1339 patients younger than 70 years and 143 patients 70 years or older. A marked difference in treatment was noted, even after stratifying by disease stage. Only 21% of the older patients underwent surgical treatment compared with 27.6% of the younger. After adjusting for confounding variables, the hazard ratio for death from CC in the elderly was 1.05 (95% confidence interval, 0.81-1.36; P = 0.11). These results corroborate previous data from developed countries: elderly patients have more advanced disease at diagnosis, and age is an important factor in the allocation of treatment for patients with CC. Worse outcome seemed to be mainly the result of more advanced stage and treatment allocation rather than age itself.

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Mesh:

Year:  2016        PMID: 27465885     DOI: 10.1097/IGC.0000000000000756

Source DB:  PubMed          Journal:  Int J Gynecol Cancer        ISSN: 1048-891X            Impact factor:   3.437


  9 in total

1.  Quality of life among survivors of early-stage cervical cancer in Taiwan: an exploration of treatment modality differences.

Authors:  Chia-Chun Li; Ting-Chang Chang; Yun-Fang Tsai; Lynn Chen
Journal:  Qual Life Res       Date:  2017-06-12       Impact factor: 4.147

2.  Understanding cervical cancer after the age of routine screening: Characteristics of cases, treatment, and survival in the United States.

Authors:  Katie E Lichter; Kimberly Levinson; Anne Hammer; Melissa H Lippitt; Anne F Rositch
Journal:  Gynecol Oncol       Date:  2022-02-01       Impact factor: 5.482

3.  Characteristics and Treatments of Patients Aged 65 Years or Over with Cervical Cancer.

Authors:  Shangdan Xie; Shuya Pan; Shuangwei Zou; Haiyan Zhu; Xueqiong Zhu
Journal:  Clin Interv Aging       Date:  2020-06-03       Impact factor: 4.458

4.  Selective use of concurrent chemotherapy in elderly cervical cancer patients treated with definitive radiotherapy: experience from two institutions.

Authors:  Kai-Yun You; Hai-Hua Peng; Yan-Hui Jiang; Zhuo-Fei Bi; Xing-Sheng Qiu
Journal:  Cancer Manag Res       Date:  2019-05-27       Impact factor: 3.989

5.  Clinicopathological Features and Survival of Adolescent and Young Adults with Cervical Cancer.

Authors:  Shuya Pan; Wenxiao Jiang; Shangdan Xie; Haiyan Zhu; Xueqiong Zhu
Journal:  Cancer Control       Date:  2021 Jan-Dec       Impact factor: 3.302

6.  Prognostic Analysis and Comparison of the 2014 and 2018 International Federation of Gynecology and Obstetrics Staging System on Overall Survival in Patients with Stage IIB-IVA Cervix Carcinoma.

Authors:  Tao Song; Hong'en Xu; Lei Shi; Senxiang Yan
Journal:  Int J Womens Health       Date:  2022-03-06

7.  Evaluation of elderly women with uterin cervical cancer.

Authors:  Özer Birge; Mehmet Sait Bakır; Ceyda Karadag; Selen Doğan; Hasan Aykut Tuncer; Tayup Simsek
Journal:  Cancer Rep (Hoboken)       Date:  2021-10-10

8.  Outcome and toxicity of radical radiotherapy or concurrent Chemoradiotherapy for elderly cervical cancer women.

Authors:  Weiping Wang; Xiaorong Hou; Junfang Yan; Jie Shen; Xin Lian; Shuai Sun; Zhikai Liu; Qingyu Meng; Dunhuang Wang; Mei Zhao; Jie Qiu; Ke Hu; Fuquan Zhang
Journal:  BMC Cancer       Date:  2017-08-01       Impact factor: 4.430

9.  The long noncoding RNA FTH1P3 promotes the proliferation and metastasis of cervical cancer through microRNA‑145.

Authors:  Rui Lv; Qian Wen Zhang
Journal:  Oncol Rep       Date:  2019-11-20       Impact factor: 3.906

  9 in total

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