Literature DB >> 27462930

Should the United States Government Repeal Restrictions on Buprenorphine/Naloxone Treatment?

Kenneth Blum1,2,3,4,5,6, Mark Gold4,5,7, H Westley Clark8, Kristina Dushaj6, Rajendra D Badgaiyan9.   

Abstract

Attention must be focused on needed changes to the current United States law that restricts physicians who prescribe buprenorphine for the detoxification or treatment of Opioid Use Disorder, to accepting no more than 100 patients. The current system does not provide comprehensive treatment as defined by the American Society of Addiction Medicine (ASAM) criteria. In addition, it suffers from both fragmentation and stigma and will require a significant change to comply with ASAM's call for integrated delivery of comprehensive addiction treatment. This commentary calls for the development and implementation of "best practice," by recommending caution in lifting the 100 patient limit until substantial achievement of this goal occurs. The authors call for an increase to 200 in the patient limit to be restricted to those physicians who are Board Certified in Addiction Medicine by the American Board of Addiction Medicine (ABAM) or in Addiction Psychiatry by the American Board of Psychiatry and Neurology (ABPN), or other responsible medical organizations. Any additional restriction lifting should follow a systemic evolution that rewards and documents competency. Such a system would involve the integration of treatment, treatment systems, and recovery with prescription medication. In addition, it should monitor emotional blunting, treatment progress and initiation of genetic addiction risk testing.

Entities:  

Keywords:  Buprenorphine; United States law; competency; drug urine testing; genetic risk; naloxone; restriction cap

Mesh:

Substances:

Year:  2016        PMID: 27462930      PMCID: PMC5055459          DOI: 10.1080/10826084.2016.1200097

Source DB:  PubMed          Journal:  Subst Use Misuse        ISSN: 1082-6084            Impact factor:   2.164


  27 in total

1.  Acute effects of sublingual buprenorphine on brain responses to heroin-related cues in early-abstinent heroin addicts: an uncontrolled trial.

Authors:  W Mei; J X Zhang; Z Xiao
Journal:  Neuroscience       Date:  2010-08-04       Impact factor: 3.590

2.  Root causes, clinical effects, and outcomes of unintentional exposures to buprenorphine by young children.

Authors:  Eric J Lavonas; William Banner; Pamela Bradt; Becki Bucher-Bartelson; Kimberly R Brown; Pradeep Rajan; Lenn Murrelle; Richard C Dart; Jody L Green
Journal:  J Pediatr       Date:  2013-08-29       Impact factor: 4.406

3.  Can the chronic administration of the combination of buprenorphine and naloxone block dopaminergic activity causing anti-reward and relapse potential?

Authors:  Kenneth Blum; Thomas J H Chen; John Bailey; Abdalla Bowirrat; John Femino; Amanda L C Chen; Thomas Simpatico; Siobhan Morse; John Giordano; Uma Damle; Mallory Kerner; Eric R Braverman; Frank Fornari; B William Downs; Cynthia Rector; Debmayla Barh; Marlene Oscar-Berman
Journal:  Mol Neurobiol       Date:  2011-09-24       Impact factor: 5.590

4.  Opioid Overdose Deaths and Florida's Crackdown on Pill Mills.

Authors:  Alene Kennedy-Hendricks; Matthew Richey; Emma E McGinty; Elizabeth A Stuart; Colleen L Barry; Daniel W Webster
Journal:  Am J Public Health       Date:  2015-12-21       Impact factor: 9.308

Review 5.  A primary care approach to substance misuse.

Authors:  Brad Shapiro; Diana Coffa; Elinore F McCance-Katz
Journal:  Am Fam Physician       Date:  2013-07-15       Impact factor: 3.292

6.  Neurogenetic Impairments of Brain Reward Circuitry Links to Reward Deficiency Syndrome (RDS): Potential Nutrigenomic Induced Dopaminergic Activation.

Authors:  K Blum; M Oscar-Berman; J Giordano; Bw Downs; T Simpatico; D Han; John Femino
Journal:  J Genet Syndr Gene Ther       Date:  2012-10-17

7.  Long term Suboxone™ emotional reactivity as measured by automatic detection in speech.

Authors:  Edward Hill; David Han; Pierre Dumouchel; Najim Dehak; Thomas Quatieri; Charles Moehs; Marlene Oscar-Berman; John Giordano; Thomas Simpatico; Debmalya Barh; Kenneth Blum
Journal:  PLoS One       Date:  2013-07-09       Impact factor: 3.240

8.  Coupling Genetic Addiction Risk Score (GARS) with Electrotherapy: Fighting Iatrogenic Opioid Dependence.

Authors:  Kenneth Blum; Marlene Oscar-Berman; Nicholas Dinubile; John Giordano; Eric R Braverman; Courtney E Truesdell; Debmalya Barh; Rajendra Badgaiyan
Journal:  J Addict Res Ther       Date:  2013-10-31

9.  Genetic Addiction Risk Score (GARS): molecular neurogenetic evidence for predisposition to Reward Deficiency Syndrome (RDS).

Authors:  Kenneth Blum; Marlene Oscar-Berman; Zsolt Demetrovics; Debmalya Barh; Mark S Gold
Journal:  Mol Neurobiol       Date:  2014-05-31       Impact factor: 5.590

10.  Systematic evaluation of "compliance" to prescribed treatment medications and "abstinence" from psychoactive drug abuse in chemical dependence programs: data from the comprehensive analysis of reported drugs.

Authors:  Kenneth Blum; David Han; John Femino; David E Smith; Scott Saunders; Thomas Simpatico; Stephen J Schoenthaler; Marlene Oscar-Berman; Mark S Gold
Journal:  PLoS One       Date:  2014-09-23       Impact factor: 3.240

View more
  9 in total

1.  Fifty Years in the Development of a Glutaminergic-Dopaminergic Optimization Complex (KB220) to Balance Brain Reward Circuitry in Reward Deficiency Syndrome: A Pictorial.

Authors:  K Blum; M Febo; R D Badgaiyan
Journal:  Austin Addict Sci       Date:  2016-10-12

2.  The relationship between treatment accessibility and preference amongst out-of-treatment individuals who engage in non-medical prescription opioid use.

Authors:  Andrew S Huhn; D Andrew Tompkins; Kelly E Dunn
Journal:  Drug Alcohol Depend       Date:  2017-09-09       Impact factor: 4.492

3.  Why aren't physicians prescribing more buprenorphine?

Authors:  Andrew S Huhn; Kelly E Dunn
Journal:  J Subst Abuse Treat       Date:  2017-04-12

4.  Death by Opioids: Are there non-addictive scientific solutions?

Authors:  B William Downs; Kenneth Blum; David Baron; Abdalla Bowirrat; Lisa Lott; Raymond Brewer; Brent Boyett; David Siwicki; A Kenison Roy; Arwen Podesta; Sampada Badgaiyan; Raju Hajela; Lyle Fried; Rajendra D Badgaiyan
Journal:  J Syst Integr Neurosci       Date:  2019-10-31

5.  Hypothesizing that a Pro-Dopaminergic Regulator (KB220z Liquid Variant) can Induce "Dopamine Homeostasis" and Provide Adjunctive Detoxification Benefits in Opiate/Opioid Dependence.

Authors:  Kenneth Blum; Debra Whitney; Lye Fried; Marcelo Febo; Roger L Waite; Eric R Braverman; Kristina Dushaj; Mona Li; John Giordano; Zsolt Demetrovics; Rajendra D Badgaiyan
Journal:  Clin Med Rev Case Rep       Date:  2016-08-16

6.  "Pro-dopamine regulation (KB220Z™)" as a long-term therapeutic modality to overcome reduced resting state dopamine tone in opiate/opioid epidemic in America.

Authors:  K Blum; F Marcelo; K Dushaj; L Fried; R D Badgaiyan
Journal:  J Syst Integr Neurosci       Date:  2016-09

7.  "Dopamine homeostasis" requires balanced polypharmacy: Issue with destructive, powerful dopamine agents to combat America's drug epidemic.

Authors:  Kenneth Blum; Edward J Modestino; Marjorie Gondré-Lewis; B William Downs; David Baron; Bruce Steinberg; David Siwicki; John Giordano; Thomas McLaughlin; Jennifer Neary; Mary Hauser; Lyle Fried; Rajendra D Badgaiyan
Journal:  J Syst Integr Neurosci       Date:  2017-11-17

8.  Responses among substance abuse treatment providers to the opioid epidemic in the USA: Variations in buprenorphine and methadone treatment by geography, operational, and payment characteristics, 2007-16.

Authors:  Justin C Yang; Andres Roman-Urrestarazu; Carol Brayne
Journal:  PLoS One       Date:  2020-03-03       Impact factor: 3.240

9.  Critical Analysis of White House Anti-Drug Plan.

Authors:  Kenneth Blum; Lyle Fried; Margaret A Madigan; John Giordano; Edward J Modestino; Bruce Steinberg; David Baron; Michael DeLeon; Thomas McLaughlin; Mary Hauser; Rajendra D Badgaiyan
Journal:  Glob J Addict Rehabil Med       Date:  2017-04-27
  9 in total

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