| Literature DB >> 27456221 |
Ignasi Bros1, Pere Notó2, Antoni Bulbena3.
Abstract
An open prospective controlled study was designed to compare the efficacy of short-term dynamic group psychotherapy with the standard treatment in patients with depressive symptoms attended in the primary care setting. A total of 115 patients with depressive symptoms were assigned to receive psychotherapy (75 min) over 9 months (37 to 39 sessions) (n = 70) or the standard care (n = 45). Outcome measures were the differences between baseline and post-treatment in the 17-item Hamilton Depression Rating Scale (HDRS), Hamilton Anxiety Rating Scale (HAM-A) and the Short-Form Health Survey (SF-12) questionnaire in the two study groups. At the end of dynamic group psychotherapy, statistically significant improvements in the mean scores of all questionnaires were observed, whereas in control patients, significant improvements were only observed in the HDRS-17 scale and in the Mental Component Summary score of the SF-12. The mean changes after treatment were also higher in the psychotherapy group than in controls in all outcome measures, with statistically significant differences in the mean differences in favour of the psychotherapy group. In summary, implementation of short-term dynamic group psychotherapy run by experienced psychotherapists for patients with depressive symptoms attended in routine primary care centres is feasible and effective.Entities:
Keywords: Depressive Symptoms; Dynamic Group Psychotherapy; Primary Care; Prospective Controlled Study
Mesh:
Year: 2016 PMID: 27456221 PMCID: PMC5574004 DOI: 10.1002/cpp.2029
Source DB: PubMed Journal: Clin Psychol Psychother ISSN: 1063-3995
Figure 1Flow chart of the patients included in the dynamic group psychotherapy and in the control group
Demographic features and psychiatric diagnosis in the study groups at the time of recruitment
| Psychotherapy group ( | Control group ( |
| |
|---|---|---|---|
| Gender | |||
| Males | 25 (35.7) | 8 (17.8) | .038 |
| Females | 45 (64.3) | 37 (82.2) | |
| Age, years, mean (SD) | 49.1 (15.04) | 48.4 (12.3) | .803 |
| Diagnoses | |||
| Dysthymia | 14 (20) | 7 (15.5) | .492 |
| Cyclothymia | 0 | 1 (2.2) | |
| Major depressive disorder | 36 (51.4) | 27 (60) | |
| Adjustment disorder | 20 (28.6) | 10 (22.2) | |
| Completed the study ( | Did not complete the study ( | ||
| Gender | |||
| Males | 25 (28.1) | 8 (30.8) | .790 |
| Females | 64 (71.9) | 18 (69.2) | |
| Age, years, mean (SD) | 48.5 (13.6) | 50.0 (15.6) | .624 |
| Diagnoses | |||
| Major depressive disorder | 49 (55.1) | 15 (57.4) | .543 |
| Dysthymia | 19 (21.3) | 3 (11.5) | |
| Adjustment disorder | 21 (23.6) | 8 (30.8) | |
| HAM‐A, mean (SD) | |||
| Psychic anxiety | 16.12 (4.78) | 15.38 (3.99) | .433 |
| Somatic anxiety | 12.08 (5.90) | 12.38 (5.12) | .797 |
| Total score | 28.15 (9.30) | 27.53 (8.04) | .737 |
| HDRS‐17 total score, mean (SD) | 20.23 (5.26) | 19.38 (6.03) | .581 |
| PCS score, mean (SD) | 41.13 (8.70) | 42.15 (10.27) | .647 |
| MCS score, mean (SD) | 30.34 (8.33) | 31.19 (10.83) | .712 |
Included one case of cyclothymia.
Data as numbers and percentages in parenthesis unless otherwise stated.
Mean (SD) scores at baseline and at the end of the study in patients undergoing dynamic group psychotherapy and in controls
| Dynamic group psychotherapy | Control group | |||||||
|---|---|---|---|---|---|---|---|---|
| No. patients | Baseline | Post‐treatment |
| No. patients | Baseline | At 9 months |
| |
| HAM‐A | ||||||||
| Psychic anxiety | ||||||||
| ITT data set | 70 | 15.43 (4.14) | 10.13 (4.69) | <.001 | 45 | 15.73 (4.25) | 15.02 (5.23) | .182 |
| PP data set | 58 | 15.62 (4.19) | 9.22 (4.33) | <.001 | 31 | 14.94 (3.59) | 13.9 (4.95) | .184 |
| Somatic anxiety | ||||||||
| ITT data set | 70 | 12.53 (5.34) | 6.87 (4.55) | <.001 | 45 | 11.71 (4.61) | 12.06 (5.91) | .697 |
| PP data set | 58 | 12.74 (5.38) | 5.91 (3.79) | <.001 | 31 | 11.98 (5.24) | 12.22 (6.05) | .699 |
| Total score | ||||||||
| ITT data set | 70 | 27.80 (8.39) | 17.0 (8.25) | <.001 | 45 | 27.47 (8.25) | 27.24 (10.18) | .830 |
| PP data set | 58 | 28.19 (8.64) | 15.16 (7.25) | <.001 | 31 | 26.29 (6.73) | 25.97 (9.83) | .831 |
| HDRS‐17 total score | ||||||||
| ITT data set | 70 | 19.26 (6.03) | 9.73 (6.38) | <.001 | 45 | 20.07 (5.59) | 18.18 (6.36) | .029 |
| PP data set | 58 | 19.31 (6.21) | 7.81 (4.67) | <.001 | 31 | 19.52 (5.79) | 16.77 (6.45) | .028 |
| PCS score | ||||||||
| ITT data set | 70 | 41.37 (10.1) | 44.19 (10.21) | .010 | 45 | 42.79 (9.73) | 43.29 (11.52) | .428 |
| PP data set | 58 | 41.89 (10.36) | 45.29 (10.27) | .010 | 31 | 42.64 (10.3) | 40.99 (10.8) | .431 |
| MCS | ||||||||
| ITT data set | 70 | 31.78 (11.3) | 42.43 (10.89) | <.001 | 45 | 29.78 (8.47) | 33.18 (11.13) | .020 |
| PP data set | 58 | 31.71 (12) | 45.17 (10.13) | <.001 | 31 | 30.21 (8.39) | 35.16 (11.6) | .019 |
HAM‐A = Hamilton Anxiety Rating Scale. ITT = intention to treat. PP = per protocol. HDRS‐17 = 17‐item Hamilton Depression Rating Scale. PCS = Physical Component Summary. MCS = Mental Component Summary.
Mean (SD) changes after treatment and mean differences in the two study groups
| Mean (SD) changes after treatment | Mean differences (95% confidence interval) |
| ||||
|---|---|---|---|---|---|---|
| No. patients | Psychotherapy group | No. patients | Control group | |||
| HAM‐A | ||||||
| Psychic anxiety | ||||||
| ITT data set | 70 | −5.30 (5.36) | 45 | −0.71 (3.52) | 4.58 (2.94 to 6.23) | <.001 |
| PP data set | 58 | −6.39 (5.26) | 31 | −1.03 (4.22) | 5.36 (2.94 to 6.23) | <. 001 |
| Somatic anxiety | ||||||
| ITT data set | 70 | −5.65 (5.56) | 45 | 0.24 (4.18) | 5.90 (4.09 to 7.70) | <.001 |
| PP data set | 58 | −6.82 (5.42) | 31 | 0.35 (5.06) | 7.18 (4.83 to 9.52) | <. 001 |
| Total score | ||||||
| ITT data set | 70 | −10.08 (9.69) | 45 | −0.22 (6.89) | 10.57 (7.50 to 13.64) | <.001 |
| PP data set | 58 | −23.03 (9.16) | 31 | −0.32 (8.35) | 12.71 (8.77 to 16.64) | <. 001 |
| HDRS‐17 total score | ||||||
| ITT data set | 70 | −9.52 (6.71) | 45 | −1.88 (5.59) | 7.63 (5.25 to 10.02) | <.001 |
| PP data set | 58 | −11.50 (5.61) | 31 | −2.74 (6.59) | 8.75 (6.11 to 11.39) | <. 001 |
| PCS score | ||||||
| ITT data set | 70 | 2.82 (8.90) | 45 | −1.34 (9.50) | 3.95 (0.49 to 7.41) | .026 |
| PP data set | 58 | 3.40 (9.69) | 31 | −1.64 (11.48) | 5.05 (0.47 to 9.62) | .031 |
| MCS | ||||||
| ITT data set | 70 | 11.14 (14.1) | 45 | 3.40 (9.47) | 7.73 (3.38 to 12.09) | .001 |
| PP data set | 58 | 13.45 (14.7) | 31 | 4.94 (11.13) | 8.5 (2.57 to 14.3) | .005 |
HAM‐A = Hamilton Anxiety Rating Scale. ITT = intention to treat. PP = per protocol. HDRS‐17 = 17‐item Hamilton Depression Rating Scale. PCS = Physical Component Summary. MCS = Mental Component Summary.
Figure 2Correlation between severity of depressive symptoms at baseline and improvement after treatment (PP population)
Figure 3Correlation between severity of anxiety at baseline and improvement after treatment (PP population)