Literature DB >> 2745261

Enhancement of opsonophagocytosis of Bacteroides spp. by clindamycin in subinhibitory concentrations.

E M Veringa1, D W Lambe, D A Ferguson, J Verhoef.   

Abstract

Radioactively labelled bacteria were incubated overnight in the presence or absence of one-half the MIC of clindamycin, then preopsonized with normal human serum or homologous rabbit antiserum and incubated with human polymorphonuclear leucocytes. Clindamycin in subinhibitory concentrations significantly enhanced the phagocytosis of all four Bacteroides strains. Complement-dependent as well as antibody-dependent phagocytosis was enhanced by clindamycin in one Bacteroides strain. In the other three strains, only antibody dependent phagocytosis was enhanced by clindamycin. Transmission electron microscopy confirmed phagocytosis of the bacteroides.

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Year:  1989        PMID： 2745261     DOI： 10.1093/jac/23.4.577

Source DB:  PubMed          Journal:  J Antimicrob Chemother        ISSN： 0305-7453            Impact factor:   5.790


  7 in total

1.  Subinhibitory antimicrobial concentrations: A review of in vitro and in vivo data.

Authors:  G G Zhanel; D J Hoban; G K Harding
Journal:  Can J Infect Dis       Date:  1992-07

Review 2.  Effects of anti-infectious agents on polymorphonuclear neutrophils.

Authors:  M T Labro; J el Benna
Journal:  Eur J Clin Microbiol Infect Dis       Date:  1991-02       Impact factor: 3.267

3.  Pretreatment of mice with clindamycin improves survival of endotoxic shock by modulating the release of inflammatory cytokines.

Authors:  N Hirata; K Hiramatsu; K Kishi; T Yamasaki; T Ichimiya; M Nasu
Journal:  Antimicrob Agents Chemother       Date:  2001-09       Impact factor: 5.191

4.  Clindamycin suppresses endotoxin released by ceftazidime-treated Escherichia coli O55:B5 and subsequent production of tumor necrosis factor alpha and interleukin-1 beta.

Authors:  K Kishi; K Hirai; K Hiramatsu; T Yamasaki; M Nasu
Journal:  Antimicrob Agents Chemother       Date:  1999-03       Impact factor: 5.191

Review 5.  A Review: Antimicrobial Therapy for Human Pythiosis.

Authors:  Sadeep Medhasi; Ariya Chindamporn; Navaporn Worasilchai
Journal:  Antibiotics (Basel)       Date:  2022-03-26

6.  Antimicrobial prophylaxis for major head and neck surgery in cancer patients: sulbactam-ampicillin versus clindamycin-amikacin.

Authors:  M Phan; P Van der Auwera; G Andry; M Aoun; G Chantrain; R Deraemaecker; P Dor; D Daneau; P Ewalenko; F Meunier
Journal:  Antimicrob Agents Chemother       Date:  1992-09       Impact factor: 5.191

7.  An unreported clindamycin adverse reaction: wrist monoarthritis.

Authors:  Ahmad Alikhani; Ebrahim Salehifar
Journal:  Iran J Pharm Res       Date:  2012       Impact factor: 1.696
  7 in total

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