Nadia Afrin1, Risto Honkanen2, Heli Koivumaa-Honkanen3, Pyry Lukkala4, Toni Rikkonen2, Joonas Sirola5, Lana J Williams6, Heikki Kröger5. 1. Kuopio Musculoskeletal Research Unit (KMRU), Surgery, Institute of Clinical Medicine, University of Eastern Finland (UEF), Kuopio, Finland. Electronic address: nadia.ziaul@gmail.com. 2. Kuopio Musculoskeletal Research Unit (KMRU), Surgery, Institute of Clinical Medicine, University of Eastern Finland (UEF), Kuopio, Finland. 3. Institute of Clinical Medicine, Psychiatry, UEF, Kuopio, Finland; Department of Psychiatry: Kuopio University Hospital (KUH), Kuopio; South-Savonia Hospital District, Mikkeli; North Karelia Central Hospital, Joensuu; SOSTERI, Savonlinna; SOTE, Iisalmi; Lapland Hospital District, Rovaniemi, Finland. 4. School of Medicine, Faculty of Health Sciences, University of Eastern Finland (UEF), Kuopio, Finland. 5. Kuopio Musculoskeletal Research Unit (KMRU), Surgery, Institute of Clinical Medicine, University of Eastern Finland (UEF), Kuopio, Finland; Department of Orthopaedics, Traumatology and Handsurgery, Kuopio University Hospital (KUH), Kuopio, Finland. 6. IMPACT Strategic Research Centre, School of Medicine, Deakin University, Geelong, Australia.
Abstract
OBJECTIVE: To ascertain whether the risk of falls of different types is related to morbidity (number of chronic medical conditions) among postmenopausal women. STUDY DESIGN: This cohort study uses data from a population-based prospective cohort study (OSTPRE). The study population consisted of 10,594 women aged 47-56 years living in Kuopio Province, Eastern Finland, in 1989, who responded to postal enquiries at both baseline and 5-year follow-up, in 1994. Morbidity (i.e. number of diagnosed chronic medical conditions) was reported in 1989 and falls in 1994. Falls were categorized as slip or nonslip, and 'frequent falls' was defined as two or more in a 12-month period. RESULTS: The risk (odds ratio (OR) with 95% CI) of a fall increased with the number of chronic medical conditions. The OR was 1.28 (1.17-1.40) for those with 1-2 conditions and 1.41 (1.24-1.60) for those with multimorbidity (≥3 conditions) compared with healthy respondents. Multimorbidity was associated with a greater risk of the woman experiencing frequent nonslip falls (OR=2.57; 2.01-3.29) than frequent slip falls (OR=1.46; 1.17-1.80). Adjusting with logistic regression for age, number of medications and smoking did not affect the risk estimates. CONCLUSION: Multimorbidity has a much smaller effect on slip than on nonslip falls in postmenopausal women. This should be taken into account when investigating the effects of multimorbidity on fall risk in varying weather conditions.
OBJECTIVE: To ascertain whether the risk of falls of different types is related to morbidity (number of chronic medical conditions) among postmenopausal women. STUDY DESIGN: This cohort study uses data from a population-based prospective cohort study (OSTPRE). The study population consisted of 10,594 women aged 47-56 years living in Kuopio Province, Eastern Finland, in 1989, who responded to postal enquiries at both baseline and 5-year follow-up, in 1994. Morbidity (i.e. number of diagnosed chronic medical conditions) was reported in 1989 and falls in 1994. Falls were categorized as slip or nonslip, and 'frequent falls' was defined as two or more in a 12-month period. RESULTS: The risk (odds ratio (OR) with 95% CI) of a fall increased with the number of chronic medical conditions. The OR was 1.28 (1.17-1.40) for those with 1-2 conditions and 1.41 (1.24-1.60) for those with multimorbidity (≥3 conditions) compared with healthy respondents. Multimorbidity was associated with a greater risk of the woman experiencing frequent nonslip falls (OR=2.57; 2.01-3.29) than frequent slip falls (OR=1.46; 1.17-1.80). Adjusting with logistic regression for age, number of medications and smoking did not affect the risk estimates. CONCLUSION: Multimorbidity has a much smaller effect on slip than on nonslip falls in postmenopausal women. This should be taken into account when investigating the effects of multimorbidity on fall risk in varying weather conditions.
Authors: N Afrin; R Sund; R Honkanen; H Koivumaa-Honkanen; T Rikkonen; L Williams; H Kröger Journal: Osteoporos Int Date: 2019-12-19 Impact factor: 4.507
Authors: Louis Jacob; Jae Il Shin; Karel Kostev; Josep Maria Haro; Guillermo F López-Sánchez; Lee Smith; Ai Koyanagi Journal: J Clin Med Date: 2022-07-31 Impact factor: 4.964
Authors: Lee Smith; Jae Il Shin; Louis Jacob; Guillermo F López Sánchez; Felipe Schuch; Mark A Tully; Hans Oh; Nicola Veronese; Pinar Soysal; Laurie Butler; Yvonne Barnett; Ai Koyanagi Journal: Eur J Nutr Date: 2022-09-21 Impact factor: 4.865