Literature DB >> 27448452

Emergence of Mycoplasma genitalium strains showing mutations associated with macrolide and fluoroquinolone resistance in the region Dresden, Germany.

Roger Dumke1, Alexander Thürmer2, Enno Jacobs2.   

Abstract

Among 323 specimens from male patients with symptoms of non-gonococcal urethritis, Mycoplasma genitalium was detected in 19 samples by real-time PCR. Mutations of 23S rRNA gene associated with macrolide resistance were confirmed in 10 strains. Amino acid changes at positions 81 and 83 of ParC protein were demonstrated indicating quinolone resistance of two strains.
Copyright © 2016 Elsevier Inc. All rights reserved.

Entities:  

Keywords:  23S rRNA mutation; Genotyping; Macrolide resistance; Mycoplasma genitalium; Quinolone resistance; Topoisomerase mutation

Mesh：

Substances：

Year:  2016        PMID： 27448452     DOI： 10.1016/j.diagmicrobio.2016.07.005

Source DB:  PubMed          Journal:  Diagn Microbiol Infect Dis        ISSN： 0732-8893            Impact factor:   2.803


  19 in total

1.  Mycoplasma genitalium in Symptomatic Male Urethritis: Macrolide Use Is Associated With Increased Resistance.

Authors:  Yang Li; Xiaohong Su; Wenjing Le; Sai Li; Zhaoyan Yang; Christine Chaisson; Guillermo Madico; Xiangdong Gong; George W Reed; Baoxi Wang; Peter A Rice
Journal:  Clin Infect Dis       Date:  2020-02-14       Impact factor: 9.079

Review 2.  [Non-viral sexually transmitted infections - Epidemiology, clinical manifestations, diagnostics and therapy : Part 2: Chlamydia and mycoplasma].

Authors:  P Nenoff; A Manos; I Ehrhard; C Krüger; U Paasch; P Helmbold; W Handrick
Journal:  Hautarzt       Date:  2017-01       Impact factor: 0.751

3.  Mycoplasma genitalium Infection in Kenyan and US Women.

Authors:  Jennifer E Balkus; Lisa E Manhart; Jørgen S Jensen; Omu Anzala; Joshua Kimani; Jane Schwebke; Juma Shafi; Charles Rivers; Emanuel Kabare; R Scott McClelland
Journal:  Sex Transm Dis       Date:  2018-08       Impact factor: 2.830

4.  Evaluation of the ResistancePlus MG FleXible Cartridge for Near-Point-of-Care Testing of Mycoplasma genitalium and Associated Macrolide Resistance Mutations.

Authors:  E L Sweeney; L P Mhango; S Ebeyan; L Y Tan; C Bletchly; G R Nimmo; D M Whiley
Journal:  J Clin Microbiol       Date:  2020-02-24       Impact factor: 5.948

Review 5.  Developing a Public Health Response to Mycoplasma genitalium.

Authors:  Matthew R Golden; Kimberly A Workowski; Gail Bolan
Journal:  J Infect Dis       Date:  2017-07-15       Impact factor: 5.226

Review 6.  New Horizons in Mycoplasma genitalium Treatment.

Authors:  Catriona S Bradshaw; Jorgen S Jensen; Ken B Waites
Journal:  J Infect Dis       Date:  2017-07-15       Impact factor: 5.226

7.  Mycoplasma genitalium Macrolide and Fluoroquinolone Resistance Detection and Clinical Implications in a Selected Cohort in New Zealand.

Authors:  Trevor Anderson; Edward Coughlan; Anja Werno
Journal:  J Clin Microbiol       Date:  2017-09-06       Impact factor: 5.948

8.  Mycoplasma genitalium Infections With Macrolide and Fluoroquinolone Resistance-Associated Mutations in Heterosexual African American Couples in Alabama.

Authors:  Li Xiao; Ken B Waites; Barbara Van Der Pol; Kristal J Aaron; Edward W Hook; William M Geisler
Journal:  Sex Transm Dis       Date:  2019-01       Impact factor: 2.830

9.  Mycoplasma genitalium prevalence and macrolide resistance-associated mutations and coinfection with Chlamydia trachomatis in Southern Jutland, Denmark.

Authors:  Rasmus Desdorf; Niles Moller Andersen; Ming Chen
Journal:  APMIS       Date:  2021-10-24       Impact factor: 3.428

Review 10.  Molecular Tools for Typing Mycoplasma pneumoniae and Mycoplasma genitalium.

Authors:  Roger Dumke
Journal:  Front Microbiol       Date:  2022-06-02       Impact factor: 6.064
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