| Literature DB >> 2744793 |
D J Anderson, K Najafi, S J Tanghe, D A Evans, K L Levy, J F Hetke, X L Xue, J J Zappia, K D Wise.
Abstract
Silicon micromachining and thin-film technology have been employed to fabricate iridium stimulating arrays which can be used to excite discrete volumes of the central nervous system. Silicon multichannel probes with thicknesses ranging from 1 to 40 microns and arbitrary two-dimensional shapes can be fabricated using a high-yield, circuit-compatible process. Iridium stimulating sites are shown to have similar characteristics to iridium wire electrodes. Accelerated pulse testing with over 8 million 100 microA biphasic current pulses on 8000 microns 2 sites has demonstrated the long-term stability of iridium and activated iridium sites. In vivo tests have been performed in the central auditory pathways to demonstrate neural activation using the devices. These tests show a selective activation both as a function of site separation and site size.Entities:
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Year: 1989 PMID: 2744793 DOI: 10.1109/10.32101
Source DB: PubMed Journal: IEEE Trans Biomed Eng ISSN: 0018-9294 Impact factor: 4.538