Literature DB >> 27440971

Hypertension and Migraine in the Northern Manhattan Study.

Hannah Gardener1, Teshamae Monteith1, Tatjana Rundek1, Clinton B Wright1, Mitchell S V Elkind2, Ralph L Sacco1.   

Abstract

OBJECTIVE: To investigate the association between migraine and hypertension in the Northern Manhattan Study (NOMAS), a multiethnic community-based sample.
DESIGN: Cross-sectional cohort study. PARTICIPANTS: 1338 NOMAS participants (mean age 68.1 ± 9.6 years, 37% male, 15% non-Hispanic White, 19% non-Hispanic Black, 67% Hispanic).
SETTING: Northern Manhattan community. INTERVENTION: Participants were assessed for migraine symptoms using a self-report questionnaire based on criteria from the International Classification of Headache Disorders. Hypertension was defined as blood pressure ≥140/90 mm Hg, the patient's self-reported hypertension, or use of anti-hypertensive medications. Duration (≤9 years vs >9 years) and control (BP<140/90) of hypertension were examined. We estimated the association between hypertension and migraine (overall and with/without aura) using logistic regression, adjusting for sociodemographic and vascular risk factors.
RESULTS: The majority of participants (80%) had no migraine, 6% had migraine with aura, and 15% had migraine without aura. Hypertension was present in 76% of the study population (7% had controlled hypertension ≤9 years duration, 5% controlled hypertension >9 years duration, 41% uncontrolled hypertension ≤9 years duration, 23% uncontrolled hypertension >9 years duration). Hypertension was associated with migraine (OR: 1.76, 95% CI: 1.21-2.54), both with and without aura. This association was particularly apparent for those with uncontrolled and long duration hypertension.
CONCLUSION: Hypertension, particularly uncontrolled and of long duration, is associated with migraine, both with and without aura, in a predominantly Hispanic community-based cohort.

Entities:  

Keywords:  Aura; Epidemiology; Ethnicity; Hypertension; Migraine; Race

Mesh:

Substances:

Year:  2016        PMID: 27440971      PMCID: PMC4948798          DOI: 10.18865/ed.26.3.323

Source DB:  PubMed          Journal:  Ethn Dis        ISSN: 1049-510X            Impact factor:   1.847


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