Literature DB >> 27439765

Fluorescent vinblastine probes for live cell imaging.

Labros G Meimetis1, Randy J Giedt1, Hannes Mikula1, Jonathan C Carlson1, Rainer H Kohler1, David B Pirovich1, Ralph Weissleder2.   

Abstract

Herein we describe the synthesis of several fluorescent analogues of the clinically approved microtubule destabilizing agent vinblastine. The evaluated probes are the most potent described and provides the first example of uptake, distribution and live cell imaging using this well known antimitotic agent.

Entities:  

Mesh：

Substances：

Year:  2016        PMID： 27439765      PMCID： PMC4970878          DOI： 10.1039/c6cc04129a

Source DB:  PubMed          Journal:  Chem Commun (Camb)        ISSN： 1359-7345            Impact factor:   6.222


  23 in total

1.  Dissociation of tubulin assembly-inhibiting and aggregation-promoting activities by a vinblastine derivative.

Authors:  S S Rai; J Wolff
Journal:  FEBS Lett       Date:  1997-10-27       Impact factor: 4.124

2.  In vitro vinblastine-induced tubulin paracrystals.

Authors:  G C Na; S N Timasheff
Journal:  J Biol Chem       Date:  1982-09-10       Impact factor: 5.157

3.  Effect of microtubule-associated proteins on the interaction of vincristine with microtubules and tubulin.

Authors:  J A Donoso; K M Haskins; R H Himes
Journal:  Cancer Res       Date:  1979-05       Impact factor: 12.701

Review 4.  Microtubule-binding agents: a dynamic field of cancer therapeutics.

Authors:  Charles Dumontet; Mary Ann Jordan
Journal:  Nat Rev Drug Discov       Date:  2010-10       Impact factor: 84.694

5.  Structural basis for the regulation of tubulin by vinblastine.

Authors:  Benoît Gigant; Chunguang Wang; Raimond B G Ravelli; Fanny Roussi; Michel O Steinmetz; Patrick A Curmi; André Sobel; Marcel Knossow
Journal:  Nature       Date:  2005-05-26       Impact factor: 49.962

6.  4',6-Diamidino-2-phenylindole, a fluorescent probe for tubulin and microtubules.

Authors:  D Bonne; C Heuséle; C Simon; D Pantaloni
Journal:  J Biol Chem       Date:  1985-03-10       Impact factor: 5.157

Review 7.  Treatment of metastatic melanoma: an overview.

Authors:  Shailender Bhatia; Scott S Tykodi; John A Thompson
Journal:  Oncology (Williston Park)       Date:  2009-05       Impact factor: 2.990

8.  Calmodulin-containing substructures of the centrosomal matrix released by microtubule perturbation.

Authors:  Nicoleta Moisoi; Muriel Erent; Sheena Whyte; Stephen Martin; Peter M Bayley
Journal:  J Cell Sci       Date:  2002-06-01       Impact factor: 5.285

9.  Monoalkoxy BODIPYs--a fluorophore class for bioimaging.

Authors:  Alexandra M Courtis; Sofia A Santos; Yinghua Guan; J Adam Hendricks; Balaram Ghosh; D Miklos Szantai-Kis; Surya A Reis; Jagesh V Shah; Ralph Mazitschek
Journal:  Bioconjug Chem       Date:  2014-05-14       Impact factor: 4.774

10.  Postpolymerization detyrosination of alpha-tubulin: a mechanism for subcellular differentiation of microtubules.

Authors:  G G Gundersen; S Khawaja; J C Bulinski
Journal:  J Cell Biol       Date:  1987-07       Impact factor: 10.539
View more
  4 in total

1.  Imaging of Tie2 with a Fluorescently Labeled Small Molecule Affinity Ligand.

Authors:  Peter David Koch; Maaz S Ahmed; Rainer H Kohler; Ran Li; Ralph Weissleder
Journal:  ACS Chem Biol       Date:  2019-12-13       Impact factor: 5.100

2.  Measurement of drug-target engagement in live cells by two-photon fluorescence anisotropy imaging.

Authors:  Claudio Vinegoni; Paolo Fumene Feruglio; Christian Brand; Sungon Lee; Antoinette E Nibbs; Shawn Stapleton; Sunil Shah; Ignacy Gryczynski; Thomas Reiner; Ralph Mazitschek; Ralph Weissleder
Journal:  Nat Protoc       Date:  2017-06-29       Impact factor: 13.491

3.  Quantitating drug-target engagement in single cells in vitro and in vivo.

Authors:  J Matthew Dubach; Eunha Kim; Katherine Yang; Michael Cuccarese; Randy J Giedt; Labros G Meimetis; Claudio Vinegoni; Ralph Weissleder
Journal:  Nat Chem Biol       Date:  2016-12-05       Impact factor: 15.040

4.  SMALL MOLECULE IMAGING AGENT FOR MUTANT KRAS G12C.

Authors:  Peter D Koch; Jeremy Quintana; Maaz Ahmed; Rainer H Kohler; Ralph Weissleder
Journal:  Adv Ther (Weinh)       Date:  2021-03-12
  4 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.