Literature DB >> 27437284

Schimidt Syndrome: An Unusual Cause of Hypercalcaemia.

Nisha Jose1, George Prashanth Kurian2.   

Abstract

Autoimmune polyglandular syndrome type 2 also known as Schmidt syndrome. It is a rare disorder involving a combination of Addison's disease with autoimmune thyroid disease with or without type 1 diabetes mellitus. In this case report one such patient with this rare syndrome is described who presented with hyperpigmentation of knuckles, palms and soles with significant weight loss for 2 months. At presentation she also had severe hypercalcaemia. Severe hypercalcaemia is rare and hypercalcaemia at the initial presentation of Addison's disease is also unusual. The mechanism of hypercalcaemia in addisons and management of this patient is discussed.

Entities:  

Keywords:  Autoimmune polyendocrinopathies; Hypercalcaemia; Hypocortiolism

Year:  2016        PMID: 27437284      PMCID: PMC4948460          DOI: 10.7860/JCDR/2016/16770.7783

Source DB:  PubMed          Journal:  J Clin Diagn Res        ISSN: 0973-709X


  6 in total

1.  Autoimmune adrenocortical failure in Norway autoantibodies and human leukocyte antigen class II associations related to clinical features.

Authors:  Anne Grethe Myhre; Dag E Undlien; Kristian Løvås; Sverre Uhlving; Bjørn G Nedrebø; Kristian J Fougner; Thor Trovik; Jan I Sørheim; Eystein S Husebye
Journal:  J Clin Endocrinol Metab       Date:  2002-02       Impact factor: 5.958

Review 2.  Autoimmune polyglandular syndrome Type 2: the tip of an iceberg?

Authors:  C Betterle; F Lazzarotto; F Presotto
Journal:  Clin Exp Immunol       Date:  2004-08       Impact factor: 4.330

3.  Life-threatening hypercalcaemia in association with Addisonian crisis.

Authors:  J Miell; W Wassif; A McGregor; J Butler; R Ross
Journal:  Postgrad Med J       Date:  1991-08       Impact factor: 2.401

Review 4.  Autoimmune adrenal insufficiency and autoimmune polyendocrine syndromes: autoantibodies, autoantigens, and their applicability in diagnosis and disease prediction.

Authors:  Corrado Betterle; Chiara Dal Pra; Franco Mantero; Renato Zanchetta
Journal:  Endocr Rev       Date:  2002-06       Impact factor: 19.871

Review 5.  Two types of autoimmune Addison's disease associated with different polyglandular autoimmune (PGA) syndromes.

Authors:  M Neufeld; N K Maclaren; R M Blizzard
Journal:  Medicine (Baltimore)       Date:  1981-09       Impact factor: 1.889

6.  Hypercalcemia in a patient with autoimmune polyglandular syndrome.

Authors:  Svetlana Katsnelson; Jessica Cella; Heesuk Suh; Marina M Charitou
Journal:  Clin Pract       Date:  2012-04-04
  6 in total
  1 in total

1.  Myositis, rhabdomyolysis and severe hypercalcaemia in a body builder.

Authors:  Ravikumar Ravindran; Justyna Witczak; Suhani Bahl; Lakdasa D K E Premawardhana; Mohamed Adlan
Journal:  Endocrinol Diabetes Metab Case Rep       Date:  2020-07-05
  1 in total

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