| Literature DB >> 15270837 |
C Betterle1, F Lazzarotto, F Presotto.
Abstract
Autoimmune polyglandular syndromes (APS) are conditions characterized by the association of two or more organ-specific disorders. Type 2 APS is defined by the occurrence of Addison's disease with thyroid autoimmune disease and/or Type 1 diabetes mellitus. Clinically overt disorders are considered only the tip of the autoimmune iceberg, since latent forms are much more frequent. Historical, clinical, genetic, and immunological aspects of Type 2 APS are reviewed. Furthermore, data on 146 personal cases of Type 2 APS are also reported.Entities:
Mesh:
Year: 2004 PMID: 15270837 PMCID: PMC1809126 DOI: 10.1111/j.1365-2249.2004.02561.x
Source DB: PubMed Journal: Clin Exp Immunol ISSN: 0009-9104 Impact factor: 4.330