Literature DB >> 27429528

Frequency of West Nile Virus Infection in Iranian Blood Donors.

Afsaneh Aghaie1, John Aaskov2, Sadegh Chinikar3, Matthias Niedrig4, Soudabeh Banazadeh5, Hashem Khorsand Mohammadpour6.   

Abstract

West Nile virus (WNV) can be transmitted by blood transfusions and organ transplants. This study was a retrospective study which was performed in Blood Transfusion Center to evaluate the WNV infection in blood donors in Iran. A total of 540 blood samples were taken from volunteer healthy donors who referred for blood donation to Chabahar Blood Center. The presence of WNV was studied by detecting immunoglobulin G (IgG) WNV by enzyme linked immune sorbent assay (ELISA). Demonstration of elevated WNV IgG confirmed by immunoflouorescence assay (IFA) Euroimmun kit. Out of the 540 samples 17.96 % (97 cases) were seropositive by ELISA and 1.48 % (8 cases) was seropositive by IFA. This means that 8.24 % of ELISA seropositive samples were confirmed by IFA. Special attention should be paid to criteria of donor selection, albeit positive results may be due to a previous infection in these donors.

Entities:  

Keywords:  Blood donor; Donor selection; Enzyme linked immune sorbent assay (ELISA); Epidemiology; Immunoflouorescence assay (IFA); Iran; West Nile virus (WNV)

Year:  2015        PMID： 27429528      PMCID： PMC4930752          DOI： 10.1007/s12288-015-0567-5

Source DB:  PubMed          Journal:  Indian J Hematol Blood Transfus        ISSN： 0971-4502            Impact factor:   0.900


  10 in total

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  9 in total

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