Literature DB >> 27422653

European Paediatric Formulation Initiative (EuPFI)-Formulating Ideas for Better Medicines for Children.

Smita Salunke1, Fang Liu2, Hannah Batchelor3, Jenny Walsh4, Roy Turner5, Tzuchi Rob Ju6, Catherine Tuleu7.   

Abstract

The European Paediatric Formulation Initiative (EuPFI), founded in 2007, aims to promote and facilitate the preparation of better and safe medicines for children through linking research and information dissemination. It brings together the capabilities of the industry, academics, hospitals, and regulators within a common platform in order to scope the solid understanding of the major issues, which will underpin the progress towards the future of paediatric medicines we want.The EuPFI was formed in parallel to the adoption of regulations within the EU and USA and has served as a community that drives research and dissemination through publications and the organisation of annual conferences. The membership and reach of this group have grown since its inception in 2007 and continue to develop and evolve to meet the continuing needs and ambitions of research into and development of age appropriate medicines. Five diverse workstreams (age-appropriate medicines, Biopharmaceutics, Administration Devices, Excipients and Taste Assessment & Taste Masking (TATM)) direct specific workpackages on behalf of the EuPFI. Furthermore, EuPFI interacts with multiple diverse professional groups across the globe to ensure efficient working in the area of paediatric medicines. Strong commitment and active involvement of all EuPFI stakeholders have proved to be vital to effectively address knowledge gaps related to paediatric medicines, discuss potential areas for further research and identify issues that need more attention and analysis in the future.

Entities:  

Keywords:  EuPFI; administration devices; age appropriate; biopharm; excipients; formulation; paediatric; taste assessment; taste masking

Mesh:

Substances:

Year:  2016        PMID: 27422653     DOI: 10.1208/s12249-016-0584-1

Source DB:  PubMed          Journal:  AAPS PharmSciTech        ISSN: 1530-9932            Impact factor:   3.246


  8 in total

1.  Biopharmaceutical optimization in neglected diseases for paediatric patients by applying the provisional paediatric biopharmaceutical classification system.

Authors:  Jose Manuel Del Moral Sanchez; Isabel Gonzalez-Alvarez; Aaron Cerda-Revert; Marta Gonzalez-Alvarez; Andres Navarro-Ruiz; Gordon L Amidon; Marival Bermejo
Journal:  Br J Clin Pharmacol       Date:  2018-07-17       Impact factor: 4.335

2.  Use of Adult Sensory Panel to Study Individual Differences in the Palatability of a Pediatric HIV Treatment Drug.

Authors:  Julie A Mennella; Phoebe S Mathew; Elizabeth D Lowenthal
Journal:  Clin Ther       Date:  2017-09-18       Impact factor: 3.393

Review 3.  Safety and Biopharmaceutical Challenges of Excipients in Off-Label Pediatric Formulations.

Authors:  Anteneh Belayneh; Ebisa Tadese; Fantahun Molla
Journal:  Int J Gen Med       Date:  2020-11-09

4.  Development of a Hospital Compounded, Taste-Masked, Temozolomide Oral Suspension and 5-Year Real-Life Experience in Treating Paediatric Patients.

Authors:  Maxime Annereau; Mélanie Hinterlang; Hugues Bienayme; Gilles Vassal; Antoine Pinon; Mathieu Schmitt; Lucas Denis; Caroline Lemarchand; Laurent Martin; François Lemare; Samuel Abbou; Jérémy Bastid; Lionel Tortolano
Journal:  Pharmaceuticals (Basel)       Date:  2022-04-29

5.  Suitability of new drugs registered in Brazil from 2003 to 2013 for pediatric age groups.

Authors:  Jaqueline Cristina da Silveira Xavier E Castro; Stephanie Ferreira Botelho; Taisa Roberta Lopes Machado; Maria Auxiliadora Parreiras Martins; Liliana Batista Vieira; Adriano Max Moreira Reis
Journal:  Einstein (Sao Paulo)       Date:  2018-11-08

6.  Accuracy of hydrocortisone dose administration via nasogastric tube.

Authors:  Eleni Daniel; Martin J Whitaker; Brian Keevil; Jerry Wales; Richard J Ross
Journal:  Clin Endocrinol (Oxf)       Date:  2018-11-09       Impact factor: 3.478

7.  Can children swallow tablets? Outcome data from a feasibility study to assess the acceptability of different-sized placebo tablets in children (creating acceptable tablets (CAT)).

Authors:  Louise Bracken; Emma McDonough; Samantha Ashleigh; Fiona Wilson; Joanne Shakeshaft; Udeme Ohia; Punam Mistry; Huw Jones; Nazim Kanji; Fang Liu; Matthew Peak
Journal:  BMJ Open       Date:  2020-10-10       Impact factor: 2.692

Review 8.  Excipients in the Paediatric Population: A Review.

Authors:  Khadija Rouaz; Blanca Chiclana-Rodríguez; Anna Nardi-Ricart; Marc Suñé-Pou; Dèbora Mercadé-Frutos; Josep María Suñé-Negre; Pilar Pérez-Lozano; Encarna García-Montoya
Journal:  Pharmaceutics       Date:  2021-03-13       Impact factor: 6.321

  8 in total

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