Literature DB >> 27421761

Genetic polymorphism of 22 autosomal STR markers in a Han population of Southern China.

Qiu-Ling Liu1, Zi-Xiang Chen2, Chu-Guang Chen3, De-Jian Lu4.   

Abstract

Population genetic data and forensic statistics of 22 autosomal short tandem repeat (STR) loci (D1S1656, D2S1338, D3S3045, D4S2366, D5S2500, D6S477, D7S3048, D8S1132, D9S925, D10S1435, D11S2368, D12S391, D13S325, D14S608, D15S659, D16S539, D17S1290, D18S535, D19S253, D20S470, D21S1270 and GATA198B05) were determined for a sample of 515 unrelated individuals from Han population in Southern China. The expected heterozygosity and the discrimination power varied from 0.7358 to 0.8733 and 0.8915 to 0.9702, respectively. The probability of excluding an unrelated man as the true father (assuming no background relatedness in the population) for trios and for duos ranged from 0.5126 to 0.7415 and 0.3331 to 0.5864, respectively. The studied STRs appear to provide a significant improvement in the statistical power of kinship analysis.
Copyright © 2016 Elsevier Ireland Ltd. All rights reserved.

Entities:  

Keywords:  Chinese Han population; Kinship analysis; Linkage disequilibrium; Population data; Short tandem repeats (STR)

Mesh:

Substances:

Year:  2016        PMID: 27421761     DOI: 10.1016/j.fsigen.2016.06.017

Source DB:  PubMed          Journal:  Forensic Sci Int Genet        ISSN: 1872-4973            Impact factor:   4.882


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