Literature DB >> 27417995

Rare cause of atrial fibrillation: a thymic mass.

Swati Vishwanathan1, Pritam Tayshetye2, Farshaad Bilimoria3, Gene Finley2.   

Abstract

A 62-year-old African-American man admitted to the emergency room with chest pain and exertional dyspnoea. He was found to be in rapid atrial fibrillation with pulmonary oedema. A transoesophageal echocardiogram performed prior to cardioversion showed a depressed left ventricular function (ejection fraction 30%) and an extracardiac heterogeneous echodensity compressing the right atrium and the superior vena cava. CT of the chest confirmed an anterior mediastinal mass measuring 13.5×6.6×10.1 cm, exerting a mass effect on the right atrium with mediastinal and right hilar adenopathy. CT-guided biopsy of the mediastinal mass revealed thymic carcinoma (squamous cell subtype). The metastatic workup was negative. The mass was deemed surgically unresectable due to its proximity to the heart. Chemotherapy was initiated with carboplatin/paclitaxel every 3 weeks with plans for intensity modulated radiotherapy after one to two cycles of chemotherapy. The patient recently had a repeat CT scan of the chest showing regression of the tumour. 2016 BMJ Publishing Group Ltd.

Entities:  

Mesh:

Year:  2016        PMID: 27417995      PMCID: PMC4956993          DOI: 10.1136/bcr-2016-216710

Source DB:  PubMed          Journal:  BMJ Case Rep        ISSN: 1757-790X


  12 in total

1.  Giant mediastinal teratoma presenting with paroxysmal atrial fibrillation.

Authors:  Christos Asteriou; Nikolaos Barbetakis; Athanassios Kleontas; Dimitrios Konstantinou
Journal:  Interact Cardiovasc Thorac Surg       Date:  2010-11-12

2.  Thymic epithelial tumors: comparison of CT and MR imaging findings of low-risk thymomas, high-risk thymomas, and thymic carcinomas.

Authors:  Junko Sadohara; Kiminori Fujimoto; Nestor L Müller; Seiya Kato; Shinzo Takamori; Kazuaki Ohkuma; Hiroshi Terasaki; Naofumi Hayabuchi
Journal:  Eur J Radiol       Date:  2006-10       Impact factor: 3.528

3.  Immunohistochemical markers in the differentiation of thymic and pulmonary neoplasms.

Authors:  S Pomplun; A C Wotherspoon; G Shah; P Goldstraw; G Ladas; A G Nicholson
Journal:  Histopathology       Date:  2002-02       Impact factor: 5.087

Review 4.  Staging system of thymoma.

Authors:  Akira Masaoka
Journal:  J Thorac Oncol       Date:  2010-10       Impact factor: 15.609

5.  Phase II study of carboplatin and paclitaxel in advanced thymoma and thymic carcinoma.

Authors:  Girum L Lemma; Ju-Whei Lee; Seena C Aisner; Corey J Langer; William J Tester; David H Johnson; Patrick J Loehrer
Journal:  J Clin Oncol       Date:  2011-04-18       Impact factor: 44.544

6.  The multimodality treatment of thymic carcinoma.

Authors:  M Lucchi; A Mussi; F Basolo; M C Ambrogi; G Fontanini; C A Angeletti
Journal:  Eur J Cardiothorac Surg       Date:  2001-05       Impact factor: 4.191

Review 7.  Insights into onco-cardiology: atrial fibrillation in cancer.

Authors:  Dimitrios Farmakis; John Parissis; Gerasimos Filippatos
Journal:  J Am Coll Cardiol       Date:  2013-12-18       Impact factor: 24.094

8.  Treatment and prognosis of thymic carcinoma: a retrospective analysis of 40 cases.

Authors:  Kazuhiko Ogawa; Takafumi Toita; Takashi Uno; Nobukazu Fuwa; Yasumasa Kakinohana; Minoru Kamata; Kageharu Koja; Takao Kinjo; Genki Adachi; Sadayuki Murayama
Journal:  Cancer       Date:  2002-06-15       Impact factor: 6.860

9.  Thymomas and thymic carcinomas: Clinical Practice Guidelines in Oncology.

Authors:  David S Ettinger; Gregory J Riely; Wallace Akerley; Hossein Borghaei; Andrew C Chang; Richard T Cheney; Lucian R Chirieac; Thomas A D'Amico; Todd L Demmy; Ramaswamy Govindan; Frederic W Grannis; Stefan C Grant; Leora Horn; Thierry M Jahan; Ritsuko Komaki; Feng-Ming Spring Kong; Mark G Kris; Lee M Krug; Rudy P Lackner; Inga T Lennes; Billy W Loo; Renato Martins; Gregory A Otterson; Jyoti D Patel; Mary C Pinder-Schenck; Katherine M Pisters; Karen Reckamp; Eric Rohren; Theresa A Shapiro; Scott J Swanson; Kurt Tauer; Douglas E Wood; Stephen C Yang; Kristina Gregory; Miranda Hughes
Journal:  J Natl Compr Canc Netw       Date:  2013-05-01       Impact factor: 11.908

10.  Thymic carcinoma. A clinicopathologic study of 60 cases.

Authors:  S Suster; J Rosai
Journal:  Cancer       Date:  1991-02-15       Impact factor: 6.860

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