| Literature DB >> 27414706 |
Kang Liang1, Joseph J Richardson2, Jiwei Cui3, Frank Caruso3, Christian J Doonan4, Paolo Falcaro5.
Abstract
The biomimetic mineralization of metal-organic framework (MOF) material on living cells is reported. ZIF-8 can be crystallized on a living cell surface as an exoskeleton that offers physical protection while allowing transport of essential nutrients, thus maintaining cell viability. The MOF shell prevents cell division, leading to an artificially induced pseudo-hibernation state. Cellular functions can be fully restored upon MOF removal.Entities:
Keywords: biomimetics; cell coatings; cytoprotection; metal-organic frameworks; nanoporous materials
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Year: 2016 PMID: 27414706 DOI: 10.1002/adma.201602335
Source DB: PubMed Journal: Adv Mater ISSN: 0935-9648 Impact factor: 30.849