| Literature DB >> 27410918 |
Camila Freze Baez1, Flavia Savassi-Ribas2, Wilker Menezes da Rocha2, Stéphanie G S Almeida2, Marianna T V Gonçalves2, Maria Angelica A M Guimarães1, Silvia Maria B Cavalcanti2, Rafael B Varella2.
Abstract
The aim of this study was to investigate the association of EBV and HPV with gingivitis and/or periodontitis according to the immunologic status. To this end, 74 oral biopsies from transplanted and non-transplanted individuals with the abovementioned oral manifestations were submitted to a screening by PCR for both viruses. According to the results, EBV was strongly associated with gingivitis and/or periodontitis in transplanted individuals (p = 0.011) but not HPV (p = 0.766). EBV-HPV co-detections did not enhance the presence of tissue injury as well. Although a causal relationship was not investigated in this study, the higher frequency of these two oncoviruses in lesion tissues must be investigated in follow-up studies, especially among immunocompromised individuals.Entities:
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Year: 2016 PMID： 27410918 PMCID： PMC4964327 DOI： 10.1590/S1678-9946201658058
Source DB: PubMed Journal: Rev Inst Med Trop Sao Paulo ISSN： 0036-4665 Impact factor: 1.846