Literature DB >> 27408429

Successful Management of Refractory Dialysis Independent Wegener's Granulomatosis with Combination of Therapeutic Plasma Exchange and Rituximab.

Sheetal Malhotra1, Hari Krishan Dhawan2, Ratti Ram Sharma2, Neelam Marwaha2, Aman Sharma3.   

Abstract

Wegeners granulomatosis (WG) is an autoimmune, antineutrophil cytoplasmic antibody mediated necrotizing vasculitis involving renal, and upper and lower respiratory systems. Treatment relies on a combination of immunosuppressive drugs and tapering regimen of glucocorticoids. Therapeutic plasma exchange (TPE) has been recognized as a second line treatment. We report the successful use of TPE in combination with rituximab in achieving remission in a patient with WG (dialysis independent) not responding to conventional therapy.

Entities:  

Keywords:  Rituximab; Therapeutic plasma exchange; Wegener’s granulomatosis

Year:  2015        PMID： 27408429      PMCID： PMC4925486          DOI： 10.1007/s12288-015-0507-4

Source DB:  PubMed          Journal:  Indian J Hematol Blood Transfus        ISSN： 0971-4502            Impact factor:   0.900


  13 in total

1.  Rituximab versus cyclophosphamide for ANCA-associated vasculitis.

Authors:  John H Stone; Peter A Merkel; Robert Spiera; Philip Seo; Carol A Langford; Gary S Hoffman; Cees G M Kallenberg; E William St Clair; Anthony Turkiewicz; Nadia K Tchao; Lisa Webber; Linna Ding; Lourdes P Sejismundo; Kathleen Mieras; David Weitzenkamp; David Ikle; Vicki Seyfert-Margolis; Mark Mueller; Paul Brunetta; Nancy B Allen; Fernando C Fervenza; Duvuru Geetha; Karina A Keogh; Eugene Y Kissin; Paul A Monach; Tobias Peikert; Coen Stegeman; Steven R Ytterberg; Ulrich Specks
Journal:  N Engl J Med       Date:  2010-07-15       Impact factor: 91.245

2.  Pulmonary-renal syndrome, diffuse pulmonary hemorrhage and glomerulonephritis, associated with Wegener's granulomatosis effectively treated with early plasma exchange therapy.

Authors:  Toshiro Sugimoto; Naoko Deji; Shinji Kume; Norihisa Osawa; Masayoshi Sakaguchi; Keiji Isshiki; Daisuke Koya; Atsunori Kashiwagi
Journal:  Intern Med       Date:  2007-01-01       Impact factor: 1.271

3.  Guidelines on the use of therapeutic apheresis in clinical practice-evidence-based approach from the Writing Committee of the American Society for Apheresis: the sixth special issue.

Authors:  Joseph Schwartz; Jeffrey L Winters; Anand Padmanabhan; Rasheed A Balogun; Meghan Delaney; Michael L Linenberger; Zbigniew M Szczepiorkowski; Mark E Williams; Yanyun Wu; Beth H Shaz
Journal:  J Clin Apher       Date:  2013-07       Impact factor: 2.821

4.  Plasma exchange for induction and cyclosporine A for maintenance of remission in Wegener's granulomatosis--a clinical randomized controlled trial.

Authors:  Wladimir M Szpirt; James G Heaf; Jørgen Petersen
Journal:  Nephrol Dial Transplant       Date:  2010-06-24       Impact factor: 5.992

Review 5.  Plasma exchange in the treatment of Wegener's granulomatosis, microscopic polyangiitis, Churg-Strauss syndrome and renal limited vasculitis.

Authors:  Alina Casian; David Jayne
Journal:  Curr Opin Rheumatol       Date:  2011-01       Impact factor: 5.006

6.  Plasmapheresis for diffuse alveolar hemorrhage in a patient with Wegener's granulomatosis: case report and review of the literature.

Authors:  Thong Nguyen; Meri King Martin; Alexander J Indrikovs
Journal:  J Clin Apher       Date:  2005-12       Impact factor: 2.821

7.  Progressive renal disease despite immunosuppressive therapy in a patient with Wegener s granulomatosis.

Authors:  I Klein; G Vervoort; E Steenbergen; J Wetzels
Journal:  Neth J Med       Date:  2008-03       Impact factor: 1.422

Review 8.  Treatment options for refractory Wegener's granulomatosis: a role for rituximab?

Authors:  Sabina A Antoniu
Journal:  Curr Opin Investig Drugs       Date:  2007-11

9.  Randomized trial of plasma exchange or high-dosage methylprednisolone as adjunctive therapy for severe renal vasculitis.

Authors:  David R W Jayne; Gill Gaskin; Niels Rasmussen; Daniel Abramowicz; Franco Ferrario; Loic Guillevin; Eduardo Mirapeix; Caroline O S Savage; Renato A Sinico; Coen A Stegeman; Kerstin W Westman; Fokko J van der Woude; Robert A F de Lind van Wijngaarden; Charles D Pusey
Journal:  J Am Soc Nephrol       Date:  2007-06-20       Impact factor: 10.121

10.  Therapeutic implications of coexisting severe pulmonary hemorrhage and pulmonary emboli in a case of Wegener granulomatosis.

Authors:  Gavin Dreyer; Stanley Fan
Journal:  Am J Kidney Dis       Date:  2009-03-20       Impact factor: 8.860
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  1 in total

Review 1.  [A Case Report and Literature Review of Pulmonary Wegener' Granulomatosis].

Authors:  Dian Ren; Xin Li; Minghui Liu; Jinghao Liu; Gang Chen; Chunqiu Xia; Chaoyi Jia; Jun Chen
Journal:  Zhongguo Fei Ai Za Zhi       Date:  2021-12-20
  1 in total

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