Literature DB >> 27408426

Prevalence and Viral Load of Human Parvovirus B19 (B19V) Among Blood Donors in South-East Brazil.

Svetoslav Nanev Slavov1, Katia Kaori Otaguiri2, Dimas Tadeu Covas1, Simone Kashima2.   

Abstract

The infection of human parvovirus B19 (B19V) is a common event in the general population, including volunteer blood donors. In some cases it can be asymptomatic and can remain persistent for a long period of time. The objective of this study was to examine the B19V DNA prevalence and viral load in first-time volunteer blood donors. Blood samples were collected from 91 primary blood donors at the Regional Blood Center of Ribeirão Preto, Southeast Brazil. Viral detection and quantitation was performed by an in-house TaqMan(®) real-time PCR with high sensitivity. B19V DNA was detected in one male blood donor (1.0 %) and was characterized by a very low viral load (537.36 copies/mL). Our studies demonstrate that B19V DNA at low titer may be present in apparently healthy individuals. Sensitive molecular diagnostic tools can be applied for the screening of fresh blood derived products in order to prevent transfusion-transmitted B19V infection.

Entities:  

Keywords:  B19V; Blood donors; Human parvovirus B19; Viral quantitation

Year:  2015        PMID： 27408426      PMCID： PMC4925535          DOI： 10.1007/s12288-015-0607-1

Source DB:  PubMed          Journal:  Indian J Hematol Blood Transfus        ISSN： 0971-4502            Impact factor:   0.900


  14 in total

1.  Prevalence of human erythrovirus B19 DNA in healthy Belgian blood donors and correlation with specific antibodies against structural and non-structural viral proteins.

Authors:  I Thomas; M Di Giambattista; C Gérard; E Mathys; V Hougardy; B Latour; T Branckaert; R Laub
Journal:  Vox Sang       Date:  2003-05       Impact factor: 2.144

2.  Parvovirus b19 infections and blood counts in blood donors.

Authors:  David Juhl; Dagmar Steppat; Siegfried Görg; Holger Hennig
Journal:  Transfus Med Hemother       Date:  2013-12-30       Impact factor: 3.747

3.  Prevalence and quantitation of parvovirus B19 DNA levels in blood donors with a sensitive polymerase chain reaction screening assay.

Authors:  Steven H Kleinman; Simone A Glynn; Tzong-Hae Lee; Leslie Tobler; Leilani Montalvo; Deborah Todd; Joseph E Kiss; Venkatakrishna Shyamala; Michael P Busch
Journal:  Transfusion       Date:  2007-10       Impact factor: 3.157

4.  Persistent infection by human parvovirus B19 in qualified blood donors.

Authors:  Harumichi Matsukura; Sachiko Shibata; Yoshihiko Tani; Hirotoshi Shibata; Rika A Furuta
Journal:  Transfusion       Date:  2008-05       Impact factor: 3.157

5.  Persistence of Parvovirus B19 (B19V) DNA and humoral immune response in B19V-infected blood donors.

Authors:  D Juhl; S Görg; H Hennig
Journal:  Vox Sang       Date:  2014-06-11       Impact factor: 2.144

6.  Molecular and phylogenetic analyses of human Parvovirus B19 isolated from Brazilian patients with sickle cell disease and β-thalassemia major and healthy blood donors.

Authors:  Svetoslav Nanev Slavov; Simone Kashima Haddad; Ana Cristina Silva-Pinto; Alberto Anastacio Amarilla; Helda Liz Alfonso; Victor Hugo Aquino; Dimas Tadeu Covas
Journal:  J Med Virol       Date:  2012-10       Impact factor: 2.327

7.  Persistent B19 infection in immunocompetent individuals: implications for transfusion safety.

Authors:  Jean-Jacques Lefrère; Annabelle Servant-Delmas; Daniel Candotti; Martine Mariotti; Isabelle Thomas; Yvon Brossard; François Lefrère; Robert Girot; Jean-Pierre Allain; Syria Laperche
Journal:  Blood       Date:  2005-06-23       Impact factor: 22.113

8.  The prevalence of human parvovirus B19 DNA and antibodies in blood donors from four Chinese blood centers.

Authors:  Ling Ke; Miao He; Changqing Li; Yu Liu; Lei Gao; Fuzhu Yao; Julin Li; Xinhong Bi; Yunlai Lv; Jingxing Wang; Matthew L Hirsch; Wuping Li
Journal:  Transfusion       Date:  2011-03-07       Impact factor: 3.157

9.  Epidemiology of high-level parvovirus B19 viraemia among Dutch blood donors, 2003-2009.

Authors:  K Kooistra; H J Mesman; M de Waal; M H G M Koppelman; H L Zaaijer
Journal:  Vox Sang       Date:  2010-10-15       Impact factor: 2.144

Review 10.  Human parvovirus B19.

Authors:  Erik D Heegaard; Kevin E Brown
Journal:  Clin Microbiol Rev       Date:  2002-07       Impact factor: 26.132
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  5 in total

1.  Human parvovirus B19 in patients with beta thalassemia major from Tehran, Iran.

Authors:  Seyed Ali Mohammad Arabzadeh; Farideh Alizadeh; Ahmad Tavakoli; Hamidreza Mollaei; Farah Bokharaei-Salim; Gharib Karimi; Mohammad Farahmand; Helya Sadat Mortazavi; Seyed Hamidreza Monavari
Journal:  Blood Res       Date:  2017-03-27

Review 2.  Molecular and serological markers of human parvovirus B19 infection in blood donors: A systematic review and meta-analysis.

Authors:  Mohammad Farahmand; Ahmad Tavakoli; Saied Ghorbani; Seyed Hamidreza Monavari; Seyed Jalal Kiani; Sara Minaeian
Journal:  Asian J Transfus Sci       Date:  2021-11-01

3.  Structures and implications of the nuclease domain of human parvovirus B19 NS1 protein.

Authors:  Yixi Zhang; Zhiwei Shao; Yanqing Gao; Boming Fan; Jie Yang; Xi Chen; Xin Zhao; Qiyuan Shao; Weizhen Zhang; Chulei Cao; Hehua Liu; Jianhua Gan
Journal:  Comput Struct Biotechnol J       Date:  2022-08-27       Impact factor: 6.155

Review 4.  Parvovirus B19: What Is the Relevance in Transfusion Medicine?

Authors:  David Juhl; Holger Hennig
Journal:  Front Med (Lausanne)       Date:  2018-02-01

5.  Prevalence and Phylogenetic Analysis of Parvovirus (B19V) among Blood Donors with Different Nationalities Residing in Qatar.

Authors:  Doua Abdelrahman; Duaa W Al-Sadeq; Maria K Smatti; Sara A Taleb; Raed O AbuOdeh; Enas S Al-Absi; Asmaa A Al-Thani; Peter V Coyle; Nader Al-Dewik; Ahmed A Al Qahtani; Hadi M Yassine; Gheyath K Nasrallah
Journal:  Viruses       Date:  2021-03-24       Impact factor: 5.048
  5 in total

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