Literature DB >> 27404513

Derisking Psychiatric Drug Development: The NIMH's Fast Fail Program, A Novel Precompetitive Model.

Margaret C Grabb1, Alan J Cross, William Z Potter, James T McCracken.   

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Year:  2016        PMID: 27404513      PMCID: PMC5007185          DOI: 10.1097/JCP.0000000000000536

Source DB:  PubMed          Journal:  J Clin Psychopharmacol        ISSN: 0271-0749            Impact factor:   3.153


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  19 in total

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Review 2.  Developing drug prototypes: pharmacology replaces safety and tolerability?

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3.  Public-private partnerships to revitalize psychiatric drug discovery.

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Review 4.  Lessons from 60 years of pharmaceutical innovation.

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5.  A dearth of new meds.

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Review 6.  Novel methods and technologies for 21st-century clinical trials: a review.

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Review 7.  Antipsychotic occupancy of dopamine receptors in schizophrenia.

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8.  Evaluation of the GABAergic nervous system in autistic brain: (123)I-iomazenil SPECT study.

Authors:  Tatsuo Mori; Kenji Mori; Emiko Fujii; Yoshihiro Toda; Masahito Miyazaki; Masafumi Harada; Toshiaki Hashimoto; Shoji Kagami
Journal:  Brain Dev       Date:  2011-11-17       Impact factor: 1.961

9.  Transient and steady-state auditory gamma-band responses in first-degree relatives of people with autism spectrum disorder.

Authors:  Donald C Rojas; Peter D Teale; Keeran Maharajh; Eugene Kronberg; Katie Youngpeter; Lisa B Wilson; Alissa Wallace; Susan Hepburn
Journal:  Mol Autism       Date:  2011-07-05       Impact factor: 7.509

Review 10.  GABA system dysfunction in autism and related disorders: from synapse to symptoms.

Authors:  Suzanne Coghlan; Jamie Horder; Becky Inkster; M Andreina Mendez; Declan G Murphy; David J Nutt
Journal:  Neurosci Biobehav Rev       Date:  2012-07-25       Impact factor: 8.989

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Journal:  Neuropsychopharmacology       Date:  2020-02-03       Impact factor: 7.853

2.  Mismatch negativity as an index of target engagement for excitation/inhibition-based treatment development: a double-blind, placebo-controlled, randomized, single-dose cross-over study of the serotonin type-3 receptor antagonist CVN058.

Authors:  Pejman Sehatpour; Daniel C Javitt; Heloise M De Baun; Marlene Carlson; Anna Beloborodova; David H Margolin; Mark B L Carlton; Nicola L Brice; Joshua T Kantrowitz
Journal:  Neuropsychopharmacology       Date:  2021-10-20       Impact factor: 8.294

3.  Redirecting the revolution: new developments in drug development for psychiatry.

Authors:  Linda S Brady; William Z Potter; Joshua A Gordon
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Review 4.  Promises and challenges of human computational ethology.

Authors:  Dean Mobbs; Toby Wise; Nanthia Suthana; Noah Guzmán; Nikolaus Kriegeskorte; Joel Z Leibo
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5.  A Proof-of-Mechanism Study to Test Effects of the NMDA Receptor Antagonist Lanicemine on Behavioral Sensitization in Individuals With Symptoms of PTSD.

Authors:  Marijn Lijffijt; Charles E Green; Nicholas Balderston; Tabish Iqbal; Megan Atkinson; Brittany Vo-Le; Bylinda Vo-Le; Brittany O'Brien; Christian Grillon; Alan C Swann; Sanjay J Mathew
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6.  Relationship of Brain Glutamate Response to D-Cycloserine and Lurasidone to Antidepressant Response in Bipolar Depression: A Pilot Study.

Authors:  Zhengchao Dong; Michael F Grunebaum; Martin J Lan; Vashti Wagner; Tse-Hwei Choo; Matthew S Milak; Tarek Sobeih; J John Mann; Joshua T Kantrowitz
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  6 in total

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