Literature DB >> 21827111

A dearth of new meds.

Kenneth I Kaitin1, Christopher P Milne.   

Abstract

Mesh：

Year:  2011        PMID： 21827111     DOI： 10.1038/scientificamerican0811-16

Source DB:  PubMed          Journal:  Sci Am        ISSN： 0036-8733            Impact factor:   2.142


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  17 in total

1.  Derisking Psychiatric Drug Development: The NIMH's Fast Fail Program, A Novel Precompetitive Model.

Authors:  Margaret C Grabb; Alan J Cross; William Z Potter; James T McCracken
Journal:  J Clin Psychopharmacol       Date:  2016-10       Impact factor: 3.153

Review 2.  Lost but making progress--Where will new analgesic drugs come from?

Authors:  David Borsook; Richard Hargreaves; Chas Bountra; Frank Porreca
Journal:  Sci Transl Med       Date:  2014-08-13       Impact factor: 17.956

3.  Advances in understanding Alzheimer's disease, and the contributions of current Alzheimer research: ten years on and beyond.

Authors:  Nigel H Greig; Debomoy K Lahiri
Journal:  Curr Alzheimer Res       Date:  2014-02       Impact factor: 3.498

4.  Insights Into the Molecular Mechanism of Triptan Transport by P-glycoprotein.

Authors:  Laura A Wilt; Diana Nguyen; Arthur G Roberts
Journal:  J Pharm Sci       Date:  2017-03-07       Impact factor: 3.534

5.  A Conformationally Gated Model of Methadone and Loperamide Transport by P-Glycoprotein.

Authors:  Morgan E Gibbs; Laura A Wilt; Kaitlyn V Ledwitch; Arthur G Roberts
Journal:  J Pharm Sci       Date:  2018-02-28       Impact factor: 3.534

Review 6.  Medications development to treat alcohol dependence: a vision for the next decade.

Authors:  Raye Z Litten; Mark Egli; Markus Heilig; Changhai Cui; Joanne B Fertig; Megan L Ryan; Daniel E Falk; Howard Moss; Robert Huebner; Antonio Noronha
Journal:  Addict Biol       Date:  2012-03-28       Impact factor: 4.280

Review 7.  Discovery, Development, and Adoption of Medications to Treat Alcohol Use Disorder: Goals for the Phases of Medications Development.

Authors:  Raye Z Litten; Daniel E Falk; Megan L Ryan; Joanne B Fertig
Journal:  Alcohol Clin Exp Res       Date:  2016-05-17       Impact factor: 3.455

Review 8.  Deriving therapies for children with primary CNS tumors using pharmacokinetic modeling and simulation of cerebral microdialysis data.

Authors:  M O Jacus; S L Throm; D C Turner; Y T Patel; B B Freeman; M Morfouace; N Boulos; C F Stewart
Journal:  Eur J Pharm Sci       Date:  2013-11-20       Impact factor: 4.384

Review 9.  Medication Nonadherence, "Professional Subjects," and Apparent Placebo Responders: Overlapping Challenges for Medications Development.

Authors:  David J McCann; Nancy M Petry; Anders Bresell; Eva Isacsson; Ellis Wilson; Robert C Alexander
Journal:  J Clin Psychopharmacol       Date:  2015-10       Impact factor: 3.153

Review 10.  Microdialysis Monitoring in Clinical Traumatic Brain Injury and Its Role in Neuroprotective Drug Development.

Authors:  Eric Peter Thelin; Keri L H Carpenter; Peter J Hutchinson; Adel Helmy
Journal:  AAPS J       Date:  2017-01-09       Impact factor: 4.009
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