Literature DB >> 27402831

cis-Prenyltransferase: New Insights into Protein Glycosylation, Rubber Synthesis, and Human Diseases.

Kariona A Grabińska1, Eon Joo Park1, William C Sessa2.   

Abstract

cis-Prenyltransferases (cis-PTs) constitute a large family of enzymes conserved during evolution and present in all domains of life. cis-PTs catalyze consecutive condensation reactions of allylic diphosphate acceptor with isopentenyl diphosphate (IPP) in the cis (Z) configuration to generate linear polyprenyl diphosphate. The chain lengths of isoprenoid carbon skeletons vary widely from neryl pyrophosphate (C10) to natural rubber (C>10,000). The homo-dimeric bacterial enzyme, undecaprenyl diphosphate synthase (UPPS), has been structurally and mechanistically characterized in great detail and serves as a model for understanding the mode of action of eukaryotic cis-PTs. However, recent experiments have revealed that mammals, fungal, and long-chain plant cis-PTs are heteromeric enzymes composed of two distantly related subunits. In this review, the classification, function, and evolution of cis-PTs will be discussed with a special emphasis on the role of the newly described NgBR/Nus1 subunit and its plants' orthologs as essential, structural components of the cis-PTs activity.
© 2016 by The American Society for Biochemistry and Molecular Biology, Inc.

Entities:  

Keywords:  DHDDS; NUS1; NgBR; RER2; cis-prenyltransferase; dolichol; enzyme; genetic disease; glycosylation; glycosylphosphatidylinositol (GPI anchor); hCIT; lipid; polyprenol; polyprenol synthesis

Mesh：

Substances：

Year:  2016        PMID： 27402831      PMCID： PMC5000101          DOI： 10.1074/jbc.R116.739490

Source DB:  PubMed          Journal:  J Biol Chem        ISSN： 0021-9258            Impact factor:   5.157


  89 in total

1.  Cloning, expression, and characterization of cis-polyprenyl diphosphate synthase from the thermoacidophilic archaeon Sulfolobus acidocaldarius.

Authors:  H Hemmi; S Yamashita; T Shimoyama; T Nakayama; T Nishino
Journal:  J Bacteriol       Date:  2001-01       Impact factor: 3.490

2.  Mutation of Nogo-B receptor, a subunit of cis-prenyltransferase, causes a congenital disorder of glycosylation.

Authors:  Eon Joo Park; Kariona A Grabińska; Ziqiang Guan; Viktor Stránecký; Hana Hartmannová; Kateřina Hodaňová; Veronika Barešová; Jana Sovová; Levente Jozsef; Nina Ondrušková; Hana Hansíková; Tomáš Honzík; Jiří Zeman; Helena Hůlková; Rong Wen; Stanislav Kmoch; William C Sessa
Journal:  Cell Metab       Date:  2014-07-24       Impact factor: 27.287

3.  Identification of a receptor necessary for Nogo-B stimulated chemotaxis and morphogenesis of endothelial cells.

Authors:  Robert Qing Miao; Yuan Gao; Kenneth D Harrison; Jay Prendergast; Lisette M Acevedo; Jun Yu; Fenghua Hu; Stephen M Strittmatter; William C Sessa
Journal:  Proc Natl Acad Sci U S A       Date:  2006-07-11       Impact factor: 11.205

4.  Comparative Analysis of Archaeal Lipid-linked Oligosaccharides That Serve as Oligosaccharide Donors for Asn Glycosylation.

Authors:  Yuya Taguchi; Daisuke Fujinami; Daisuke Kohda
Journal:  J Biol Chem       Date:  2016-03-25       Impact factor: 5.157

5.  Whole-exome sequencing links a variant in DHDDS to retinitis pigmentosa.

Authors:  Stephan Züchner; Julia Dallman; Rong Wen; Gary Beecham; Adam Naj; Amjad Farooq; Martin A Kohli; Patrice L Whitehead; William Hulme; Ioanna Konidari; Yvonne J K Edwards; Guiqing Cai; Inga Peter; David Seo; Joseph D Buxbaum; Jonathan L Haines; Susan Blanton; Juan Young; Eduardo Alfonso; Jeffery M Vance; Byron L Lam; Margaret A Peričak-Vance
Journal:  Am J Hum Genet       Date:  2011-02-03       Impact factor: 11.025

6.  Use of genomics to identify bacterial undecaprenyl pyrophosphate synthetase: cloning, expression, and characterization of the essential uppS gene.

Authors:  C M Apfel; B Takács; M Fountoulakis; M Stieger; W Keck
Journal:  J Bacteriol       Date:  1999-01       Impact factor: 3.490

7.  Prenyltransferases of Bacillus subtilis: undecaprenyl pyrophosphate synthetase and geranylgeranyl pyrophosphate synthetase.

Authors:  I Takahashi; K Ogura
Journal:  J Biochem       Date:  1982-11       Impact factor: 3.387

8.  Long-term effect of cyclic AMP on N-glycosylation is caused by an increase in the activity of the cis-prenyltransferase.

Authors:  M Konrad; W E Merz
Journal:  Biochem J       Date:  1996-06-01       Impact factor: 3.857

9.  Efficient in vitro synthesis of cis-polyisoprenes using a thermostable cis-prenyltransferase from a hyperthermophilic archaeon Thermococcus kodakaraensis.

Authors:  Yosuke Yamada; Wakao Fukuda; Kazutake Hirooka; Takeshi Hiromoto; Jun-Ichi Nakayama; Tadayuki Imanaka; Ei-Ichiro Fukusaki; Shinsuke Fujiwara
Journal:  J Biotechnol       Date:  2009-07-05       Impact factor: 3.307

10.  Structure and inhibition of tuberculosinol synthase and decaprenyl diphosphate synthase from Mycobacterium tuberculosis.

Authors:  Hsiu-Chien Chan; Xinxin Feng; Tzu-Ping Ko; Chun-Hsiang Huang; Yumei Hu; Yingying Zheng; Shannon Bogue; Chiaki Nakano; Tsutomu Hoshino; Lilan Zhang; Pin Lv; Wenting Liu; Dean C Crick; Po-Huang Liang; Andrew H-J Wang; Eric Oldfield; Rey-Ting Guo
Journal:  J Am Chem Soc       Date:  2014-02-05       Impact factor: 15.419
View more
  20 in total

1.  Structure of undecaprenyl pyrophosphate synthase from Acinetobacter baumannii.

Authors:  Tzu Ping Ko; Chi Hung Huang; Shu Jung Lai; Yeh Chen
Journal:  Acta Crystallogr F Struct Biol Commun       Date:  2018-11-16       Impact factor: 1.056

2.  Progressive myoclonus epilepsies-Residual unsolved cases have marked genetic heterogeneity including dolichol-dependent protein glycosylation pathway genes.

Authors:  Carolina Courage; Karen L Oliver; Eon Joo Park; Jillian M Cameron; Kariona A Grabińska; Mikko Muona; Laura Canafoglia; Antonio Gambardella; Edith Said; Zaid Afawi; Betul Baykan; Christian Brandt; Carlo di Bonaventura; Hui Bein Chew; Chiara Criscuolo; Leanne M Dibbens; Barbara Castellotti; Patrizia Riguzzi; Angelo Labate; Alessandro Filla; Anna T Giallonardo; Geza Berecki; Christopher B Jackson; Tarja Joensuu; John A Damiano; Sara Kivity; Amos Korczyn; Aarno Palotie; Pasquale Striano; Davide Uccellini; Loretta Giuliano; Eva Andermann; Ingrid E Scheffer; Roberto Michelucci; Melanie Bahlo; Silvana Franceschetti; William C Sessa; Samuel F Berkovic; Anna-Elina Lehesjoki
Journal:  Am J Hum Genet       Date:  2021-04-01       Impact factor: 11.025

3.  Overexpression and Purification of Human Cis-prenyltransferase in Escherichia coli.

Authors:  Ilan Edri; Michal Goldenberg; Michal Lisnyansky; Roi Strulovich; Hadas Newman; Anat Loewenstein; Daniel Khananshvili; Moshe Giladi; Yoni Haitin
Journal:  J Vis Exp       Date:  2017-08-03       Impact factor: 1.355

4.  A conserved C-terminal RXG motif in the NgBR subunit of cis-prenyltransferase is critical for prenyltransferase activity.

Authors:  Kariona A Grabińska; Ban H Edani; Eon Joo Park; Jan R Kraehling; William C Sessa
Journal:  J Biol Chem       Date:  2017-08-23       Impact factor: 5.157

5.  Structural elucidation of the cis-prenyltransferase NgBR/DHDDS complex reveals insights in regulation of protein glycosylation.

Authors:  Ban H Edani; Kariona A Grabińska; Rong Zhang; Eon Joo Park; Benjamin Siciliano; Liliana Surmacz; Ya Ha; William C Sessa
Journal:  Proc Natl Acad Sci U S A       Date:  2020-08-12       Impact factor: 11.205

6.  Polyprenols Are Synthesized by a Plastidial cis-Prenyltransferase and Influence Photosynthetic Performance.

Authors:  Tariq A Akhtar; Przemysław Surowiecki; Hanna Siekierska; Magdalena Kania; Kristen Van Gelder; Kevin A Rea; Lilia K A Virta; Maritza Vatta; Katarzyna Gawarecka; Jacek Wojcik; Witold Danikiewicz; Daniel Buszewicz; Ewa Swiezewska; Liliana Surmacz
Journal:  Plant Cell       Date:  2017-06-27       Impact factor: 11.277

7.  High Rate of Recurrent De Novo Mutations in Developmental and Epileptic Encephalopathies.

Authors:  Fadi F Hamdan; Candace T Myers; Patrick Cossette; Philippe Lemay; Dan Spiegelman; Alexandre Dionne Laporte; Christina Nassif; Ousmane Diallo; Jean Monlong; Maxime Cadieux-Dion; Sylvia Dobrzeniecka; Caroline Meloche; Kyle Retterer; Megan T Cho; Jill A Rosenfeld; Weimin Bi; Christine Massicotte; Marguerite Miguet; Ledia Brunga; Brigid M Regan; Kelly Mo; Cory Tam; Amy Schneider; Georgie Hollingsworth; David R FitzPatrick; Alan Donaldson; Natalie Canham; Edward Blair; Bronwyn Kerr; Andrew E Fry; Rhys H Thomas; Joss Shelagh; Jane A Hurst; Helen Brittain; Moira Blyth; Robert Roger Lebel; Erica H Gerkes; Laura Davis-Keppen; Quinn Stein; Wendy K Chung; Sara J Dorison; Paul J Benke; Emily Fassi; Nicole Corsten-Janssen; Erik-Jan Kamsteeg; Frederic T Mau-Them; Ange-Line Bruel; Alain Verloes; Katrin Õunap; Monica H Wojcik; Dara V F Albert; Sunita Venkateswaran; Tyson Ware; Dean Jones; Yu-Chi Liu; Shekeeb S Mohammad; Peyman Bizargity; Carlos A Bacino; Vincenzo Leuzzi; Simone Martinelli; Bruno Dallapiccola; Marco Tartaglia; Lubov Blumkin; Klaas J Wierenga; Gabriela Purcarin; James J O'Byrne; Sylvia Stockler; Anna Lehman; Boris Keren; Marie-Christine Nougues; Cyril Mignot; Stéphane Auvin; Caroline Nava; Susan M Hiatt; Martina Bebin; Yunru Shao; Fernando Scaglia; Seema R Lalani; Richard E Frye; Imad T Jarjour; Stéphanie Jacques; Renee-Myriam Boucher; Emilie Riou; Myriam Srour; Lionel Carmant; Anne Lortie; Philippe Major; Paola Diadori; François Dubeau; Guy D'Anjou; Guillaume Bourque; Samuel F Berkovic; Lynette G Sadleir; Philippe M Campeau; Zoha Kibar; Ronald G Lafrenière; Simon L Girard; Saadet Mercimek-Mahmutoglu; Cyrus Boelman; Guy A Rouleau; Ingrid E Scheffer; Heather C Mefford; Danielle M Andrade; Elsa Rossignol; Berge A Minassian; Jacques L Michaud
Journal:  Am J Hum Genet       Date:  2017-11-02       Impact factor: 11.025

8.  Long-Chain Polyprenols Promote Spore Wall Formation in Saccharomyces cerevisiae.

Authors:  Reuben Hoffmann; Kariona Grabińska; Ziqiang Guan; William C Sessa; Aaron M Neiman
Journal:  Genetics       Date:  2017-10-04       Impact factor: 4.562

9.  Depletion of essential isoprenoids and ER stress induction following acute liver-specific deletion of HMG-CoA reductase.

Authors:  Marco De Giorgi; Kelsey E Jarrett; Jason C Burton; Alexandria M Doerfler; Ayrea Hurley; Ang Li; Rachel H Hsu; Mia Furgurson; Kalyani R Patel; Jun Han; Christoph H Borchers; William R Lagor
Journal:  J Lipid Res       Date:  2020-10-27       Impact factor: 5.922

10.  Knockdown of Dehydrodolichyl Diphosphate Synthase in the Drosophila Retina Leads to a Unique Pattern of Retinal Degeneration.

Authors:  Tal Brandwine; Reut Ifrah; Tzofia Bialistoky; Rachel Zaguri; Elisheva Rhodes-Mordov; Liliana Mizrahi-Meissonnier; Dror Sharon; Vladimir L Katanaev; Offer Gerlitz; Baruch Minke
Journal:  Front Mol Neurosci       Date:  2021-07-05       Impact factor: 5.639
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.