| Literature DB >> 27401965 |
Ryan S Austin1, Shu Hiu1, Jamie Waese1, Matthew Ierullo1, Asher Pasha1, Ting Ting Wang1, Jim Fan1, Curtis Foong1, Robert Breit1, Darrell Desveaux1, Alan Moses1, Nicholas J Provart1.
Abstract
Identifying sets of genes that are specifically expressed in certain tissues or in response to an environmental stimulus is useful for designing reporter constructs, generating gene expression markers, or for understanding gene regulatory networks. We have developed an easy-to-use online tool for defining a desired expression profile (a modification of our Expression Angler program), which can then be used to identify genes exhibiting patterns of expression that match this profile as closely as possible. Further, we have developed another online tool, Cistome, for predicting or exploring cis-elements in the promoters of sets of co-expressed genes identified by such a method, or by other methods. We present two use cases for these tools, which are freely available on the Bio-Analytic Resource at http://BAR.utoronto.ca.Entities:
Keywords: zzm321990Arabidopsis thalianazzm321990; cis-element prediction; coexpression analysis; gene expression markers; promoter analysis; reporter constructs; technical advance
Mesh:
Year: 2016 PMID: 27401965 DOI: 10.1111/tpj.13261
Source DB: PubMed Journal: Plant J ISSN: 0960-7412 Impact factor: 6.417