Literature DB >> 27400897

Seeking a Cure for One of the Rarest Diseases: Progeria.

Francis S Collins1.   

Abstract

Keywords:  Editorials; everolimus; lamin type A; lonafarnib; morpholinos; progeria; rare diseases; translational medical research

Mesh：

Substances：

Year:  2016        PMID： 27400897      PMCID： PMC5101939          DOI： 10.1161/CIRCULATIONAHA.116.022965

Source DB:  PubMed          Journal:  Circulation        ISSN： 0009-7322            Impact factor:   29.690


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  14 in total

1.  Lamin a truncation in Hutchinson-Gilford progeria.

Authors:  Annachiara De Sandre-Giovannoli; Rafaëlle Bernard; Pierre Cau; Claire Navarro; Jeanne Amiel; Irène Boccaccio; Stanislas Lyonnet; Colin L Stewart; Arnold Munnich; Martine Le Merrer; Nicolas Lévy
Journal:  Science       Date:  2003-04-17       Impact factor: 47.728

2.  Impact of farnesylation inhibitors on survival in Hutchinson-Gilford progeria syndrome.

Authors:  Leslie B Gordon; Joe Massaro; Ralph B D'Agostino; Susan E Campbell; Joan Brazier; W Ted Brown; Monica E Kleinman; Mark W Kieran
Journal:  Circulation       Date:  2014-05-02       Impact factor: 29.690

3.  Rapamycin reverses cellular phenotypes and enhances mutant protein clearance in Hutchinson-Gilford progeria syndrome cells.

Authors:  Kan Cao; John J Graziotto; Cecilia D Blair; Joseph R Mazzulli; Michael R Erdos; Dimitri Krainc; Francis S Collins
Journal:  Sci Transl Med       Date:  2011-06-29       Impact factor: 17.956

4.  Progeria: a paradigm for translational medicine.

Authors:  Leslie B Gordon; Frank G Rothman; Carlos López-Otín; Tom Misteli
Journal:  Cell       Date:  2014-01-30       Impact factor: 41.582

5.  Recurrent de novo point mutations in lamin A cause Hutchinson-Gilford progeria syndrome.

Authors:  Maria Eriksson; W Ted Brown; Leslie B Gordon; Michael W Glynn; Joel Singer; Laura Scott; Michael R Erdos; Christiane M Robbins; Tracy Y Moses; Peter Berglund; Amalia Dutra; Evgenia Pak; Sandra Durkin; Antonei B Csoka; Michael Boehnke; Thomas W Glover; Francis S Collins
Journal:  Nature       Date:  2003-04-25       Impact factor: 49.962

6.  Reversal of the cellular phenotype in the premature aging disease Hutchinson-Gilford progeria syndrome.

Authors:  Paola Scaffidi; Tom Misteli
Journal:  Nat Med       Date:  2005-03-06       Impact factor: 53.440

7.  Combined treatment with statins and aminobisphosphonates extends longevity in a mouse model of human premature aging.

Authors:  Ignacio Varela; Sandrine Pereira; Alejandro P Ugalde; Claire L Navarro; María F Suárez; Pierre Cau; Juan Cadiñanos; Fernando G Osorio; Nicolas Foray; Juan Cobo; Félix de Carlos; Nicolas Lévy; José M P Freije; Carlos López-Otín
Journal:  Nat Med       Date:  2008-06-29       Impact factor: 53.440

Review 8.  RNA therapeutics: beyond RNA interference and antisense oligonucleotides.

Authors:  Ryszard Kole; Adrian R Krainer; Sidney Altman
Journal:  Nat Rev Drug Discov       Date:  2012-01-20       Impact factor: 84.694

9.  Progeria: translational insights from cell biology.

Authors:  Leslie B Gordon; Kan Cao; Francis S Collins
Journal:  J Cell Biol       Date:  2012-10-01       Impact factor: 10.539

10.  The decision-making process and criteria in selecting candidate drugs for progeria clinical trials.

Authors:  Leslie B Gordon; Mark W Kieran; Monica E Kleinman; Tom Misteli
Journal:  EMBO Mol Med       Date:  2016-07-01       Impact factor: 12.137
View more
  10 in total

1.  New vascular insights into premature aging.

Authors:  Charles J Lowenstein; J Allen Bennett
Journal:  J Clin Invest       Date:  2018-12-18       Impact factor: 14.808

Review 2.  Intermediate filament proteins of digestive organs: physiology and pathophysiology.

Authors:  M Bishr Omary
Journal:  Am J Physiol Gastrointest Liver Physiol       Date:  2017-03-30       Impact factor: 4.052

3.  Accelerating Precision Drug Development and Drug Repurposing by Leveraging Human Genetics.

Authors:  Jill M Pulley; Jana K Shirey-Rice; Robert R Lavieri; Rebecca N Jerome; Nicole M Zaleski; David M Aronoff; Lisa Bastarache; Xinnan Niu; Kenneth J Holroyd; Dan M Roden; Eric P Skaar; Colleen M Niswender; Lawrence J Marnett; Craig W Lindsley; Leeland B Ekstrom; Alan R Bentley; Gordon R Bernard; Charles C Hong; Joshua C Denny
Journal:  Assay Drug Dev Technol       Date:  2017-04-05       Impact factor: 1.738

Review 4.  Commonalities Between Vasculature and Bone: An Osseocentric View of Arteriosclerosis.

Authors:  Dwight A Towler
Journal:  Circulation       Date:  2017-01-24       Impact factor: 29.690

5.  A Tissue Engineered Blood Vessel Model of Hutchinson-Gilford Progeria Syndrome Using Human iPSC-derived Smooth Muscle Cells.

Authors:  Leigh Atchison; Haoyue Zhang; Kan Cao; George A Truskey
Journal:  Sci Rep       Date:  2017-08-15       Impact factor: 4.379

6.  A Cell-Intrinsic Interferon-like Response Links Replication Stress to Cellular Aging Caused by Progerin.

Authors:  Ray Kreienkamp; Simona Graziano; Nuria Coll-Bonfill; Gonzalo Bedia-Diaz; Emily Cybulla; Alessandro Vindigni; Dale Dorsett; Nard Kubben; Luis Francisco Zirnberger Batista; Susana Gonzalo
Journal:  Cell Rep       Date:  2018-02-20       Impact factor: 9.423

7.  Computational Exploration for Lead Compounds That Can Reverse the Nuclear Morphology in Progeria.

Authors:  Shailima Rampogu; Ayoung Baek; Minky Son; Amir Zeb; Chanin Park; Raj Kumar; Gihwan Lee; Donghwan Kim; Yeonuk Choi; Yeongrae Cho; Yohan Park; Seok Ju Park; Keun Woo Lee
Journal:  Biomed Res Int       Date:  2017-10-26       Impact factor: 3.411

8.  Alleviation of Senescence via ATM Inhibition in Accelerated Aging Models.

Authors:  Myeong Uk Kuk; Jae Won Kim; Young-Sam Lee; Kyung A Cho; Joon Tae Park; Sang Chul Park
Journal:  Mol Cells       Date:  2019-02-01       Impact factor: 5.034

9.  Doubled lifespan and patient-like pathologies in progeria mice fed high-fat diet.

Authors:  Ray Kreienkamp; Cyrielle Billon; Gonzalo Bedia-Diaz; Carolyn J Albert; Zacharie Toth; Andrew A Butler; Sara McBride-Gagyi; David A Ford; Angel Baldan; Thomas P Burris; Susana Gonzalo
Journal:  Aging Cell       Date:  2018-12-12       Impact factor: 9.304

10.  GCMM: graph convolution network based on multimodal attention mechanism for drug repurposing.

Authors:  Fan Zhang; Wei Hu; Yirong Liu
Journal:  BMC Bioinformatics       Date:  2022-09-13       Impact factor: 3.307
  10 in total

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