Literature DB >> 2739723

Expression of a large family of POU-domain regulatory genes in mammalian brain development.

X He1, M N Treacy, D M Simmons, H A Ingraham, L W Swanson, M G Rosenfeld.   

Abstract

A novel region referred to as the POU-domain is present in two tissue-specific transcription factors, Pit-1 and Oct-2, that activate expression of genes specifying pituitary and lymphocyte phenotypes. We report the identification of multiple new members of a large family of POU-domain genes expressed in adult brain, and document that all the known mammalian POU-domain genes, including Pit-1 and Oct-2, are expressed widely in the developing nervous system.

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Year:  1989        PMID： 2739723     DOI： 10.1038/340035a0

Source DB:  PubMed          Journal:  Nature        ISSN： 0028-0836            Impact factor:   49.962


  205 in total

1.  Emx2 is required for growth of the hippocampus but not for hippocampal field specification.

Authors:  S Tole; G Goudreau; S Assimacopoulos; E A Grove
Journal:  J Neurosci       Date:  2000-04-01       Impact factor: 6.167

2.  A minimal Bcl-x promoter is activated by Brn-3a and repressed by p53.

Authors:  K L Sugars; V Budhram-Mahadeo; G Packham; D S Latchman
Journal:  Nucleic Acids Res       Date:  2001-11-15       Impact factor: 16.971

3.  Extrapituitary TSH in early chick embryos: Pit-1 dependence?

Authors:  Amy E Murphy; Steve Harvey
Journal:  J Mol Neurosci       Date:  2002 Feb-Apr       Impact factor: 3.444

4.  A cell type-specific allele of the POU gene Oct-6 reveals Schwann cell autonomous function in nerve development and regeneration.

Authors:  Merhnaz Ghazvini; Wim Mandemakers; Martine Jaegle; Marko Piirsoo; Siska Driegen; Manousos Koutsourakis; Xsander Smit; Frank Grosveld; Dies Meijer
Journal:  EMBO J       Date:  2002-09-02       Impact factor: 11.598

Review 5.  Herpes simplex virus in the eye.

Authors:  S D Cook
Journal:  Br J Ophthalmol       Date:  1992-06       Impact factor: 4.638

6.  A novel POU family transcription factor is closely related to Brn-3 but has a distinct expression pattern in neuronal cells.

Authors:  K A Lillycrop; V S Budrahan; N D Lakin; G Terrenghi; J N Wood; J M Polak; D S Latchman
Journal:  Nucleic Acids Res       Date:  1992-10-11       Impact factor: 16.971

7.  The gene for the POU domain transcription factor Oct-6 maps to the distal end of mouse chromosome 4.

Authors:  H Rohdewohld; P Gruss
Journal:  Mamm Genome       Date:  1992       Impact factor: 2.957

8.  A novel POU homeodomain gene specifically expressed in cells of the developing mammalian nervous system.

Authors:  R G Collum; P E Fisher; M Datta; S Mellis; C Thiele; K Huebner; C M Croce; M A Israel; T Theil; T Moroy
Journal:  Nucleic Acids Res       Date:  1992-09-25       Impact factor: 16.971

9.  Oct-2 transcription factor binding activity and expression up-regulation in rat cerebral ischaemia is associated with a diminution of neuronal damage in vitro.

Authors:  Susanna Camós; Carme Gubern; Mónica Sobrado; Rocío Rodríguez; Víctor G Romera; María Ángeles Moro; Ignacio Lizasoain; Joaquín Serena; Judith Mallolas; Mar Castellanos
Journal:  Neuromolecular Med       Date:  2013-11-27       Impact factor: 3.843

10.  Mouse Brn-3 family of POU transcription factors: a new aminoterminal domain is crucial for the oncogenic activity of Brn-3a.

Authors:  T Theil; S McLean-Hunter; M Zörnig; T Möröy
Journal:  Nucleic Acids Res       Date:  1993-12-25       Impact factor: 16.971
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